Gene Symbol | Mef2b |
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Entrez Gene | 17259 |
Alt Symbol | AI451606 |
Species | Mouse |
Gene Type | protein-coding |
Description | myocyte enhancer factor 2B |
Other Description | myocyte-specific enhancer factor 2B |
Swissprots | O55087 O55088 O55089 O55090 O55231 Q61843 |
Accessions | BAA24539 EDL28788 EDL28789 O55087 BB867153 BC045147 AAH45147 CO811773 D87833 BAA24542 D87834 BAA24543 D87835 BAA24544 D87836 BAA24545 NM_001045484 NP_001038949 NM_008578 NP_032604 |
Function | Transcriptional activator which binds specifically to the MEF2 element, 5'-YTA[AT](4)TAR-3', found in numerous muscle- specific genes. Activates transcription via this element. May be involved in muscle-specific and/or growth factor-related transcription. {ECO:0000269|PubMed:8668199, ECO:0000269|PubMed:9443808}. |
Subcellular Location | Nucleus {ECO:0000255|PROSITE- ProRule:PRU00251}. |
Tissue Specificity | Highest expression found in embryonic heart and skeletal muscle. Low levels found in adult spleen, lung and testis while no expression is found in adult heart, brain or skeletal muscle. {ECO:0000269|PubMed:7646512, ECO:0000269|PubMed:8668199, ECO:0000269|PubMed:9443808}. |
Top Pathways | cGMP-PKG signaling pathway |
MEF-2B (C-6) - sc-376504 from Santa Cruz Biotechnology
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Anti-MEF2B Antibody (aa276-325) - LS-C30831 from LifeSpan Bioscience
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MEF2B Antibody - NBP1-80218 from Novus Biologicals
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Anti-MEF2B antibody produced in rabbit - AV36916 from Sigma-Aldrich
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MEF2B antibody - C-terminal region (ARP36916_T100) - ARP36916_T100 from Aviva Systems Biology
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MEF2B antibody - 70R-31811 from Fitzgerald
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MEF2B antibody - 20R-1125 from Fitzgerald
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MEF2B Antibody - 28-588 from ProSci
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MEF2B, Polyclonal Antibody - MBS835745 from MyBioSource
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MEF2B Antibody - GWB-B15C75 from Genway Biotech
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MEF2B-antibody-C-terminal-region-AI11066 - AI11066 from Abgent, a WuXi AppTec company
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MEF2B, Polyclonal Antibody - MBS5300835 from MyBioSource
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MEF2B antibody - TA341792 from Acris Antibodies
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MEF2B antibody - C-terminal region : Biotin (ARP36916_T100-Biotin) - ARP36916_T100-Biotin from Aviva Systems Biology
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MEF2B antibody - C-terminal region : FITC (ARP36916_T100-FITC) - ARP36916_T100-FITC from Aviva Systems Biology
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MEF2B antibody - C-terminal region : HRP (ARP36916_T100-HRP) - ARP36916_T100-HRP from Aviva Systems Biology
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