EXT1

Gene Symbol	EXT1
Entrez Gene	2131
Alt Symbol	EXT, LGCR, LGS, TRPS2, TTV
Species	Human
Gene Type	protein-coding
Description	exostosin glycosyltransferase 1
Other Description	Glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N- acetylglucosaminyltransferase|Langer-Giedion syndrome chromosome region|N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase|exostoses (multiple) 1|exostosin 1|exostosin-1|glucuronosyl-N-acetylglucosaminyl-proteoglycan/N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase|multiple exostoses protein 1|putative tumor suppressor protein EXT1
Swissprots	Q16394 B2R7V2 Q9BVI9
Accessions	AAC51154 ADI56520 AGT15863 AGV77097 AHB20150 EAW91972 Q16394 AK130054 AK313129 BAG35949 BC001174 AAH01174 DQ891868 ABM82794 DQ895056 ABM85982 S79639 AAB62283 NM_000127 NP_000118
Function	Glycosyltransferase required for the biosynthesis of heparan-sulfate. The EXT1/EXT2 complex possesses substantially higher glycosyltransferase activity than EXT1 or EXT2 alone. Appears to be a tumor suppressor. {ECO:0000269|PubMed:11518722}.
Subcellular Location	Endoplasmic reticulum membrane {ECO:0000269|PubMed:10679296}; Single-pass type II membrane protein {ECO:0000269|PubMed:10679296}. Golgi apparatus membrane {ECO:0000269|PubMed:10679296}; Single-pass type II membrane protein {ECO:0000269|PubMed:10679296}. Note=The EXT1/EXT2 complex is localized in the Golgi apparatus.
Tissue Specificity	Ubiquitous.
Top Pathways	Glycosaminoglycan biosynthesis - heparan sulfate / heparin

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human EXT1 ELISA Kit (Sandwich ELISA) - LS-F8320 from LifeSpan Bioscience Category ELISA Kit Prices $720.00 Sizes 1 plate Sensitivity 0.28 ng/ml Range 0.781-50 ng/ml

Exostoses 1 (EXT1), Human, ELISA Kit - SEG239Hu from ARP American Research Products Category ELISA Kit Prices $720.00 Sizes 96 t Sensitivity 0.28ng/mL Range 0.78 -50ng/mL

Exostosin-1 (EXT1), Human, ELISA Kit - CSB-EL007899HU from ARP American Research Products Category ELISA Kit Prices $615.00, $815.00 Sizes 48 t, 96 t

Exostoses 1, EXT1, Human, ELISA Kit - E-EL-H1401 from ARP American Research Products Category ELISA Kit Prices $522.00 Sizes 96 t Sensitivity 0.469 Range 0.781-50ng/mL

Transfusion transimitted virus (TTV)/hepatitis H virus antibody, Human, ELISA Kit - CSB-EQ027290HU from ARP American Research Products Category ELISA Kit Prices $550.00, $790.00, $791.00, $794.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t

Exostoses 1, EXT1, Rabbit, ELISA Kit - E-EL-RB1840 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

Exostoses 1, EXT1, Chicken, ELISA Kit - E-EL-Ch0393 from ARP American Research Products Category ELISA Kit Prices $445.50 Sizes 96 t

Exostoses 1, EXT1, Porcine, ELISA Kit - E-EL-P0878 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

Exostoses 1, EXT1, Guinea Pig, ELISA Kit - E-EL-GP0822 from ARP American Research Products Category ELISA Kit Prices $522.00 Sizes 96 t

Exostoses 1, EXT1, Monkey, ELISA Kit - E-EL-MK0981 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

Human TTV ELISA Kit - HT0561 from NeoScientific Category ELISA Kit Prices $495.00 Sizes 96 t

Anserine TTV ELISA Kit - AT0561 from NeoScientific Category ELISA Kit Prices $495.00 Sizes 96 t

Human EXT1(Exostoses 1) ELISA Kit - E-EL-H1401 from Elabscience Category ELISA Kit Sensitivity 0.47 ng/mL Range 0.78—50 ng/mL

Human EXT1 (Exostoses 1) CLIA Kit - E-CL-H0906 from Elabscience Category CLIA Kit Sensitivity 0.09 ng/mL Range Average Recovery (%)

EXT1, ELISA Kit - MBS2512931 from MyBioSource Category ELISA Kit Prices $450.00, $535.00, $2,255.00, $3,975.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.094ng/mL Range 0.156-10ng/mL

EXT1, ELISA Kit - MBS2508593 from MyBioSource Category ELISA Kit Prices $450.00, $535.00, $2,255.00, $3,975.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.469ng/mL Range 0.781-50ng/mL

EXT1, ELISA Kit - MBS2502201 from MyBioSource Category ELISA Kit Prices $450.00, $535.00, $2,255.00, $3,975.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.469ng/mL Range 0.781-50ng/mL

EXT1, ELISA Kit - MBS2508633 from MyBioSource Category ELISA Kit Prices $450.00, $535.00, $2,255.00, $3,975.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.469ng/mL Range 0.781-50ng/mL

EXT1, ELISA Kit - MBS2513756 from MyBioSource Category ELISA Kit Prices $410.00, $490.00, $2,040.00, $3,590.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity The minimum detectable dose of Human EXT1 is 0.469ng/mL (The sensitivity of this assay, or lowest detectable limit (LDL) was defined as the lowest protein concentration that could be differentiated from zero). Range 0.781-50ng/mL

EXT1, ELISA Kit - MBS2501884 from MyBioSource Category ELISA Kit Prices $450.00, $535.00, $2,255.00, $3,975.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 18.75pg/mL Range 31.25-2000pg/mL

ELISA Kit for Exostoses 1 (EXT1) - SEG239Hu from Uscn Life Science Inc. Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.28ng/mL. Range 0.781-50ng/mL The standard curve concentrations used for the ELISA’s were 50ng/mL, 25ng/mL, 12.5ng/mL, 6.25ng/mL, 3.125ng/mL, 1.563ng/mL, 0.781ng/mL

ELISA Kit for Exostoses 1 (EXT1) - SEG239Hu from Cloud-clone Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.28ng/mL. Range 0.781-50ng/mL The standard curve concentrations used for the ELISA's were 50ng/mL, 25ng/mL, 12.5ng/mL, 6.25ng/mL, 3.125ng/mL, 1.563ng/mL, 0.781ng/mL

Human GRIK2(Glutamate Receptor, Ionotropic, Kainate 2) ELISA Kit - E-EL-H1401 from Iwai North America Inc. Category ELISA Kit Prices $580.00 Sizes 1 kit Sensitivity 0.47 ng/mLng/mL Range 0.78~50 ng/mL

Human GSTKappa1(Glutathione S Transferase Kappa 1) ELISA Kit - E-EL-H1402 from Iwai North America Inc. Category ELISA Kit Prices $580.00 Sizes 1 kit Sensitivity 0.94 mU/mLmU/mL Range 1.56~100 mU/mL

Human EXT1 (Exostoses 1) CLIA Kit - E-CL-H0906 from Iwai North America Inc. Category CLIA Kit Prices $722.50 Sizes 1 kit Sensitivity 0.469ng/mL Range 0.781-50ng/mL

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