IRF9

Gene Symbol	IRF9
Entrez Gene	10379
Alt Symbol	IRF-9, ISGF3, ISGF3G, p48
Species	Human
Gene Type	protein-coding
Description	interferon regulatory factor 9
Other Description	IFN-alpha-responsive transcription factor subunit|ISGF-3 gamma|ISGF3 p48 subunit|interferon-stimulated gene factor 3 gamma|interferon-stimulated transcription factor 3, gamma (48kD)|interferon-stimulated transcription factor 3, gamma 48kDa|transcriptional regulator ISGF3 subunit gamma
Swissprots	D3DS61 Q00978
Accessions	EAW66092 EAW66093 EAW66094 Q00978 AK295467 BAG58398 AK308347 BC035716 AAH35716 BI497082 BI919023 EU446692 ABZ92221 M87503 AAA58687 U92994 NM_006084 NP_006075
Function	Transcription factor that mediates signaling by type I IFNs (IFN-alpha and IFN-beta). Following type I IFN binding to cell surface receptors, Jak kinases (TYK2 and JAK1) are activated, leading to tyrosine phosphorylation of STAT1 and STAT2. IRF9/ISGF3G associates with the phosphorylated STAT1:STAT2 dimer to form a complex termed ISGF3 transcription factor, that enters the nucleus. ISGF3 binds to the IFN stimulated response element (ISRE) to activate the transcription of interferon stimulated genes, which drive the cell in an antiviral state.
Subcellular Location	Cytoplasm {ECO:0000269|PubMed:11846981}. Nucleus {ECO:0000269|PubMed:11846981}. Note=Translocated into the nucleus upon activation by IFN-alpha/beta.
Top Pathways	Jak-STAT signaling pathway, Hepatitis C, Osteoclast differentiation, Measles, Influenza A

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human ISGF3 / IRF9 ELISA Kit (Sandwich ELISA) - LS-F6731 from LifeSpan Bioscience Category ELISA Kit Prices $720.00 Sizes 1 plate Sensitivity 0.048 ng/ml Range 0.156-10 ng/ml

Human IRF9 ELISA Kit - abx152062 from Abbexa Category ELISA Kit Sensitivity 0.042 ng/ml Range 0.156 ng/ml - 10 ng/ml

Interferon regulatory factor 9 (IRF9), Human, ELISA Kit - CSB-EL011824HU from ARP American Research Products Category ELISA Kit Prices $495.00, $695.00, $696.00, $699.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t

Interferon Regulatory Factor 9 (IRF9), Human, ELISA Kit - SEH780Hu from ARP American Research Products Category ELISA Kit Prices $720.00 Sizes 96 t Sensitivity 0.042ng/mL Range 0.156-10 ng/mL

Interferon Regulatory Factor 9, ELISA Kit - MBS096791 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Interferon Regulatory Factor 9, ELISA Kit - MBS107801 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Interferon Regulatory Factor 9, ELISA Kit - MBS095830 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Interferon Regulatory Factor 9, ELISA Kit - MBS101994 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Interferon Regulatory Factor 9, ELISA Kit - MBS077207 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Interferon Regulatory Factor 9, ELISA Kit - MBS058793 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

interferon regulatory factor 9, ELISA Kit - MBS921012 from MyBioSource Category ELISA Kit Prices $250.00, $495.00, $710.00, $2,705.00, $5,145.00 Sizes 24 -strip-wells (Limit 1), 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity The minimum detectable dose of human IRF9 is typically less than 7 pg/ml. The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined the mean O.D value of 20 replicates of the zero standard added by their three standard deviations. Range 28 pg/ml -1800 pg/ml.

Interferon Regulatory Factor 9, ELISA Kit - MBS055779 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Interferon Regulatory Factor 9 (IRF9), ELISA Kit - MBS2023237 from MyBioSource Category ELISA Kit Prices $380.00, $565.00, $765.00, $3,130.00, $5,670.00 Sizes 24 -strip-wells, 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity Typically less than 0.048ng/mL. Range 0.156-10ng/mL

ELISA Kit for Interferon Regulatory Factor 9 (IRF9) - SEH780Hu from Uscn Life Science Inc. Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.048ng/mL. Range 0.156-10ng/mL The standard curve concentrations used for the ELISA’s were 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL, 0.156ng/mL

Human Interferon regulatory factor 9(IRF9) ELISA kit - CSB-EL011824HU from Cusabio Category ELISA Kit Sensitivity 7 pg/ml Range 28 pg/ml-1800 pg/ml

ELISA Kit for Interferon Regulatory Factor 9 (IRF9) - SEH780Hu from Cloud-clone Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.048ng/mL. Range 0.156-10ng/mL The standard curve concentrations used for the ELISA's were 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL, 0.156ng/mL

Human Interferon Regulatory Factor 9 (IRF9) ELISA Kit - EKU05125 from Biomatik Category ELISA Kit Prices $735.00, $3,234.00, $5,880.00 Sizes 96 t, 5x96t, 10x96t Sensitivity 0.048 ng/mL Range 0.156-10 ng/mL

Interferon Regulatory Factor 9 (IRF9), Human, ELISA Kit - DL-IRF9-Hu from ARP American Research Products Category ELISA Kit Prices $655.00 Sizes 96 t Range 0.156-10 ng/mL

Human IRF9 ELISA Kit - abx570755 from Abbexa Category ELISA Kit Sensitivity 0.042 ng/ml Range 0.156 ng/ml - 10 ng/ml

Human Interferon regulatory factor 9 (IRF9) ELISA Kit - EKC34203 from Biomatik Category ELISA Kit Prices $705.00, $2,820.00, $5,288.00 Sizes 96 t, 5x96t, 10x96t Sensitivity 7 pg/ml Range 28 pg/ml-1800 pg/ml

Human IRF9 ELISA Kit - E020346 from Biobool Category ELISA Kit Sensitivity The minimum detectable dose of human IRF9 is typically less than 7 pg/ml. The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined the mean O

IRF9 ELISA Kit (Human) (OKDD00345) - OKDD00345 from Aviva Systems Biology Category ELISA Kit Prices $520.00 Sizes 96 wells Sensitivity < 0.042 ng/mL Range 0.156-10 ng/mL

Interferon Regulatory Factor 9 (IRF9), ELISA Kit - MBS451671 from MyBioSource Category ELISA Kit Prices $370.00, $495.00, $2,140.00, $4,155.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity <0.042ng/mL Range 0.156-10ng/mL

Interferon Regulatory Factor 9 (IRF9), ELISA Kit - MBS9380559 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Human IRF9 ELISA Kit - orb404640 from Biorbyt Category ELISA Kit Sensitivity 7 pg/ml Range 28 pg/ml-1800 pg/ml

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