NABP2

Gene Symbol NABP2
Entrez Gene 79035
Alt Symbol OBFC2B, SOSS-B1, SSB1, hSSB1
Species Human
Gene Type protein-coding
Description nucleic acid binding protein 2
Other Description LP3587|SOSS complex subunit B1|nucleic acid-binding protein 2|oligonucleotide/oligosaccharide-binding fold containing 2B|oligonucleotide/oligosaccharide-binding fold-containing protein 2B|sensor of single-strand DNA complex subunit B1|sensor of ssDNA subunit B1|single strand DNA-binding protein 1|single-stranded DNA-binding protein 1
Swissprots A6NDF8 Q9BQ15 Q6XYC8
Accessions EAW96912 EAW96913 EAW96914 EAW96915 Q9BQ15 AI038029 AY203942 AAP34465 BC001079 AAH01079 BC006171 AAH06171 BG697807 HQ447988 ADQ32470 XM_005269146 XP_005269203 XM_005269147 XP_005269204 XM_005269148 XP_005269205 XM_005269149 XP_005269206 NM_024068 NP_076973
Function Component of the SOSS complex, a multiprotein complex that functions downstream of the MRN complex to promote DNA repair and G2/M checkpoint. In the SOSS complex, acts as a sensor of single-stranded DNA that binds to single-stranded DNA, in particular to polypyrimidines. The SOSS complex associates with DNA lesions and influences diverse endpoints in the cellular DNA damage response including cell-cycle checkpoint activation, recombinational repair and maintenance of genomic stability. Required for efficient homologous recombination-dependent repair of double-strand breaks (DSBs) and ATM-dependent signaling pathways. {ECO:0000269|PubMed:18449195, ECO:0000269|PubMed:19605351, ECO:0000269|PubMed:19683501}.
Subcellular Location Nucleus {ECO:0000269|PubMed:18449195, ECO:0000269|PubMed:19605351, ECO:0000269|PubMed:19683501}. Note=Localizes to nuclear foci following DNA damage. Foci formation is not cell-cycle dependent. Partial colocalization with RAD51 after ionizing radiation treatment.

OBFC2B-Over-expression-Lysate - LY15412a from Abgent, a WuXi AppTec company

Category Cell Lysate
Prices $325.00
Sizes 100 µg
Western blot analysis of his-tag OBFC2B (arrow) using his tag antibody. 293 cell lysates (2 ug/lane) either nontransfected (Lane 2) or transiently transfected with theOBFC2B gene

OBFC2B 293T Cell Transient Overexpression Lysate(Denatured) - H00079035-T01 from Acris Antibodies

Category Cell Lysate
Prices $320.00
Sizes 100 µl

OBFC2B 293 Cell Lysate - 405718 from ABBIOTEC

Category Cell Lysate
Prices $392.00
Sizes 100 µg

OBFC2B Overexpression Lysate (Native) - NBL1-13900 from Novus Biologicals

Category Cell Lysate
Prices $329.00
Sizes 100 µg
Western Blot: OBFC2B Overexpression Lysate (Adult Normal) [NBL1-13900] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for OBFC2B.

OBFC2B Over-expression Lysate Product - GWB-D49EE4 from Genway Biotech

Category Cell Lysate
Prices $346.00
Sizes 100 µg
Species Human

OBFC2B Overexpression Lysate (Denatured) - H00079035-T01 from Novus Biologicals

Category Cell Lysate
Prices $299.00
Sizes 100 µl

Panoply™ Human NABP2 Knockdown Stable Cell Line - CSC-DC010091 from Creative biogene

Category Cell Line
Species Human

Human NABP2 Knockout Cell Line-HEK293T - CSC-RT1134 from Creative biogene

Category Cell Line
Species Human

NABP2 KO Cell Lysate-HEK293T - CLKO-0624 from Creative biogene

Category Cell Lysate
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