NABP2

Gene Symbol	NABP2
Entrez Gene	79035
Alt Symbol	OBFC2B, SOSS-B1, SSB1, hSSB1
Species	Human
Gene Type	protein-coding
Description	nucleic acid binding protein 2
Other Description	LP3587|SOSS complex subunit B1|nucleic acid-binding protein 2|oligonucleotide/oligosaccharide-binding fold containing 2B|oligonucleotide/oligosaccharide-binding fold-containing protein 2B|sensor of single-strand DNA complex subunit B1|sensor of ssDNA subunit B1|single strand DNA-binding protein 1|single-stranded DNA-binding protein 1
Swissprots	A6NDF8 Q9BQ15 Q6XYC8
Accessions	EAW96912 EAW96913 EAW96914 EAW96915 Q9BQ15 AI038029 AY203942 AAP34465 BC001079 AAH01079 BC006171 AAH06171 BG697807 HQ447988 ADQ32470 XM_005269146 XP_005269203 XM_005269147 XP_005269204 XM_005269148 XP_005269205 XM_005269149 XP_005269206 NM_024068 NP_076973
Function	Component of the SOSS complex, a multiprotein complex that functions downstream of the MRN complex to promote DNA repair and G2/M checkpoint. In the SOSS complex, acts as a sensor of single-stranded DNA that binds to single-stranded DNA, in particular to polypyrimidines. The SOSS complex associates with DNA lesions and influences diverse endpoints in the cellular DNA damage response including cell-cycle checkpoint activation, recombinational repair and maintenance of genomic stability. Required for efficient homologous recombination-dependent repair of double-strand breaks (DSBs) and ATM-dependent signaling pathways. {ECO:0000269|PubMed:18449195, ECO:0000269|PubMed:19605351, ECO:0000269|PubMed:19683501}.
Subcellular Location	Nucleus {ECO:0000269|PubMed:18449195, ECO:0000269|PubMed:19605351, ECO:0000269|PubMed:19683501}. Note=Localizes to nuclear foci following DNA damage. Foci formation is not cell-cycle dependent. Partial colocalization with RAD51 after ionizing radiation treatment.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human OBFC2B full length protein - ab163963 from Abcam Category Protein Source Wheat germ Species Human

NABP2 Antibody Blocking Peptide - LS-E1094 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human OBFC2B Protein - H00079035-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

OBFC2B-Antibody-C-term-Blocking-peptide - BP11591b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

SPSB1 protein (His tag) - 80R-1811 from Fitzgerald Category Protein Prices $340.00 Sizes 50 µg Source E.coli

OBFC2B - H00079035-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

OBFC2B - H00079035-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

OBFC2B fusion protein - Ag6532 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

OBFC2B fusion protein - Ag7116 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

Recombinant Human NABP2 - NABP2-1124H from Creative Biomart Category Protein Source Mammalian Cells Species Human

Recombinant Human OBFC2B, GST-tagged - OBFC2B-1437H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Human SOSS complex subunit B1(OBFC2B) - CSB-YP858412HU CSB-EP858412HU CSB-BP858412HU CSB-MP858412HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

Oligonucleotide/oligosaccharide-binding fold containing 2B (OBFC2B) - TP300876 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

OBFC2B Recombinant Protein Antigen - NBP1-82718PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

NABP2 Peptide, Human - M34GP10091H from Creative Peptides Category Peptide Source Synthetic. Species Human

OBFC2B Recombinant Protein Antigen - NBP2-58145PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

SOSS complex subunit B1 (OBFC2B), Recombinant Protein - MBS1369531 from MyBioSource Category Protein Prices $960.00, $960.00, $1,185.00, $1,185.00, $1,440.00, $1,440.00, $1,905.00, $1,905.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

Recombinant Human OBFC2B Protein, MYC/DDK-tagged - NABP2-190H from Creative Biomart Category Protein Source HEK293 Species Human

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