Gene Symbol | ORC6 |
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Entrez Gene | 23594 |
Alt Symbol | ORC6L |
Species | Human |
Gene Type | protein-coding |
Description | origin recognition complex, subunit 6 |
Other Description | origin recognition complex subunit 6 |
Swissprots | Q9Y5N6 B3KN89 |
Accessions | EAW82685 EAW82686 Q9Y5N6 AF139658 AAD32666 AK021946 BAG51061 AK024019 BAG51251 AK024077 BAB14817 AK310633 AM392646 CAL37524 AM392910 CAL37788 AM393680 CAL38556 BC039032 AAH39032 BC050725 BC063565 AAH63565 BG822640 XM_011522978 XP_011521280 NM_014321 NP_055136 NR_037620 |
Function | Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent. The specific DNA sequences that define origins of replication have not been identified yet. ORC is required to assemble the pre- replication complex necessary to initiate DNA replication. Does not bind histone H3 and H4 trimethylation marks H3K9me3, H3K27me3 and H4K20me3. {ECO:0000269|PubMed:22427655}. |
Subcellular Location | Nucleus. |
Top Pathways | Cell cycle |
ORC6 (3A4) Rat mAb - 4737 from Cell Signaling Technology
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ORC6 (D-4) - sc-390490 from Santa Cruz Biotechnology
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ORC6 (3A4) - sc-32735 from Santa Cruz Biotechnology
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ORC6 (FL-252) - sc-20636 from Santa Cruz Biotechnology
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ORC6 (N-17) - sc-19730 from Santa Cruz Biotechnology
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ORC6 (V-15) - sc-19731 from Santa Cruz Biotechnology
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ORC6 (2679C2b) - sc-81646 from Santa Cruz Biotechnology
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Anti-ORC6 antibody - C-terminal - ab153993 from Abcam
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Anti-ORC6L antibody - ab88686 from Abcam
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Anti-ORC6L antibody - ab168306 from Abcam
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Anti-ORC6L antibody - ab80406 from Abcam
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Anti-ORC6L antibody - ab80405 from Abcam
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Anti-ORC6L antibody [2679C2b] - ab60066 from Abcam
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Anti-ORC6L antibody [3A4] - ChIP Grade - ab22536 from Abcam
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Anti-ORC6 / ORC6L Antibody - LS-C37899 from LifeSpan Bioscience
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Anti-ORC6 / ORC6L Antibody - LS-C73918 from LifeSpan Bioscience
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Anti-ORC6 / ORC6L Antibody (clone 3A4) - LS-C82305 from LifeSpan Bioscience
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Anti-ORC6 / ORC6L Antibody (aa200-230) - LS-C288286 from LifeSpan Bioscience
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Anti-ORC6 / ORC6L Antibody (aa230-252) - LS-C288295 from LifeSpan Bioscience
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Anti-ORC6 / ORC6L Antibody (clone 2679C2b) - LS-C184597 from LifeSpan Bioscience
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Anti-ORC6 / ORC6L Antibody - LS-C334055 from LifeSpan Bioscience
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Anti-ORC6 / ORC6L Antibody (C-Terminus) - LS-C81983 from LifeSpan Bioscience
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Anti-ORC6 / ORC6L Antibody (aa23-72) - LS-C205806 from LifeSpan Bioscience
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Anti-ORC6 / ORC6L Antibody (aa241-252) - LS-C55204 from LifeSpan Bioscience
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Anti-ORC6 / ORC6L Antibody (clone 2679C2b) - LS-C342632 from LifeSpan Bioscience
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