| Gene Symbol |
ORC6
|
| Entrez Gene |
23594
|
| Alt Symbol |
ORC6L
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
origin recognition complex, subunit 6
|
| Other Description |
origin recognition complex subunit 6
|
| Swissprots |
Q9Y5N6 B3KN89
|
| Accessions |
EAW82685 EAW82686 Q9Y5N6 AF139658 AAD32666 AK021946 BAG51061 AK024019 BAG51251 AK024077 BAB14817 AK310633 AM392646 CAL37524 AM392910 CAL37788 AM393680 CAL38556 BC039032 AAH39032 BC050725 BC063565 AAH63565 BG822640 XM_011522978 XP_011521280 NM_014321 NP_055136 NR_037620
|
| Function |
Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent. The specific DNA sequences that define origins of replication have not been identified yet. ORC is required to assemble the pre- replication complex necessary to initiate DNA replication. Does not bind histone H3 and H4 trimethylation marks H3K9me3, H3K27me3 and H4K20me3. {ECO:0000269|PubMed:22427655}.
|
| Subcellular Location |
Nucleus.
|
| Top Pathways |
Cell cycle
|