Gene Symbol | ORC6 |
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Entrez Gene | 23594 |
Alt Symbol | ORC6L |
Species | Human |
Gene Type | protein-coding |
Description | origin recognition complex, subunit 6 |
Other Description | origin recognition complex subunit 6 |
Swissprots | Q9Y5N6 B3KN89 |
Accessions | EAW82685 EAW82686 Q9Y5N6 AF139658 AAD32666 AK021946 BAG51061 AK024019 BAG51251 AK024077 BAB14817 AK310633 AM392646 CAL37524 AM392910 CAL37788 AM393680 CAL38556 BC039032 AAH39032 BC050725 BC063565 AAH63565 BG822640 XM_011522978 XP_011521280 NM_014321 NP_055136 NR_037620 |
Function | Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent. The specific DNA sequences that define origins of replication have not been identified yet. ORC is required to assemble the pre- replication complex necessary to initiate DNA replication. Does not bind histone H3 and H4 trimethylation marks H3K9me3, H3K27me3 and H4K20me3. {ECO:0000269|PubMed:22427655}. |
Subcellular Location | Nucleus. |
Top Pathways | Cell cycle |
Human ORC6L full length protein - ab132266 from Abcam
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Human ORC6L full length protein - ab171477 from Abcam
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Human ORC6L peptide - ab45438 from Abcam
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ORC6 / ORC6L Antibody Blocking Peptide - LS-E25216 from LifeSpan Bioscience
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ORC6 / ORC6L Antibody Blocking Peptide - LS-E19855 from LifeSpan Bioscience
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ORC6L Recombinant Protein - H00023594-P01 from Novus Biologicals
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Recombinant Human ORC6L Protein - NBP2-23309 from Novus Biologicals
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ORC6L blocking peptide - GTX89996-PEP from GeneTex
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ORC6L Immunizing peptide - orb17289 from Biorbyt
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ORC6 protein (His tag) - 80R-3057 from Fitzgerald
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ORC6L Blocking Peptide - 33R-9488 from Fitzgerald
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ORC6L Peptide - AC21-0038-P from Abcore
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ORC6 (1-252, His-tag) - AR51175PU-N from Acris Antibodies
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ORC6 (1-252, His-tag) - AR51175PU-S from Acris Antibodies
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ORC6 - H00023594-P01-10 from Acris Antibodies
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ORC6 - H00023594-P01-25 from Acris Antibodies
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ORC6, 1-252aa, Human, His tag, E.coli - 01-P2351 from ARP American Research Products
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ORC6L Peptide - 46-103P from ProSci
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ORC6L fusion protein - ag11856 from Proteintech Group
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ORC6L fusion protein - Ag11769 from Proteintech Group
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Recombinant Human ORC6, His-tagged - ORC6-2351H from Creative Biomart
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ORC6, 1-252aa, Human, His tag, E.coli - ATGP2351 from ATGen
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ORC6 Protein - abx164558 from Abbexa
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Origin Recognition Complex, Subunit 6 Protein (Recombinant) - abx263384 from Abbexa
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ORC6 - TP309054 from Acris Antibodies
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