Gene Symbol | ORC6 |
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Entrez Gene | 23594 |
Alt Symbol | ORC6L |
Species | Human |
Gene Type | protein-coding |
Description | origin recognition complex, subunit 6 |
Other Description | origin recognition complex subunit 6 |
Swissprots | Q9Y5N6 B3KN89 |
Accessions | EAW82685 EAW82686 Q9Y5N6 AF139658 AAD32666 AK021946 BAG51061 AK024019 BAG51251 AK024077 BAB14817 AK310633 AM392646 CAL37524 AM392910 CAL37788 AM393680 CAL38556 BC039032 AAH39032 BC050725 BC063565 AAH63565 BG822640 XM_011522978 XP_011521280 NM_014321 NP_055136 NR_037620 |
Function | Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent. The specific DNA sequences that define origins of replication have not been identified yet. ORC is required to assemble the pre- replication complex necessary to initiate DNA replication. Does not bind histone H3 and H4 trimethylation marks H3K9me3, H3K27me3 and H4K20me3. {ECO:0000269|PubMed:22427655}. |
Subcellular Location | Nucleus. |
Top Pathways | Cell cycle |
ORC6L-Over-expression-Lysate - LY11882a from Abgent, a WuXi AppTec company
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ORC6L 293T Cell Transient Overexpression Lysate(Denatured) - H00023594-T01 from Acris Antibodies
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ORC6L 293T Cell Transient Overexpression Lysate(Denatured) - H00023594-T02 from Acris Antibodies
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ORC6L 293 Cell Lysate - 407237 from ABBIOTEC
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ORC6L Overexpression Lysate (Denatured) - H00023594-T02 from Novus Biologicals
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ORC6L Overexpression Lysate (Denatured) - H00023594-T01 from Novus Biologicals
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ORC6L Overexpression Lysate (Native) - NBL1-13977 from Novus Biologicals
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ORC6 (h2): 293T Lysate - sc-116694 from Santa Cruz Biotechnology
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ORC6 (h3): 293 Lysate - sc-129354 from Santa Cruz Biotechnology
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ORC6L Over-expression Lysate Product - GWB-1F2DCF from Genway Biotech
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ORC6L Overexpression Lysate (Denatured) - H00023594-T03 from Novus Biologicals
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Panoply™ Human ORC6 Knockdown Stable Cell Line - CSC-DC011128 from Creative biogene
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