SLCO1B3

Gene Symbol	SLCO1B3
Entrez Gene	28234
Alt Symbol	HBLRR, LST-2, LST-3TM13, LST3, OATP-8, OATP1B3, OATP8, SLC21A8
Species	Human
Gene Type	protein-coding
Description	solute carrier organic anion transporter family, member 1B3
Other Description	liver-specific organic anion transporter 2|liver-specific organic anion transporter 3TM13|organic anion transporter 8|organic anion transporter LST-3c|organic anion-transporting polypeptide 8|solute carrier family 21 (organic anion transporter), member 8|solute carrier organic anion transporter family member 1B3
Swissprots	E7EMT8 Q5JAR4 Q9NPD5
Accessions	CAB97008 EAW96413 EAW96414 EAW96415 Q9NPD5 AB669023 AF187815 AAG43445 AJ251506 CAB96997 AK055874 BAG51590 AY342017 AAQ19672 BC022843 AAH22843 BC058006 BC070264 AAH70264 BC105597 AAI05598 BC141525 AAI41526 BG567966 BM968322 NM_019844 NP_062818
Function	Mediates the Na(+)-independent uptake of organic anions such as 17-beta-glucuronosyl estradiol, taurocholate, triiodothyronine (T3), leukotriene C4, dehydroepiandrosterone sulfate (DHEAS), methotrexate and sulfobromophthalein (BSP). Involved in the clearance of bile acids and organic anions from the liver. {ECO:0000269|PubMed:22232210}.
Subcellular Location	Basolateral cell membrane; Multi-pass membrane protein.
Tissue Specificity	Highly expressed in liver, in particular at the basolateral membrane of hepatocytes near the central vein. Not detected in other tissues. Highly expressed in some cancer cell lines derived from colon, pancreas, liver and gall bladder.
Top Pathways	Bile secretion

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human OATP1B3/SLCO1B3 (NP_062818) VersaClone cDNA - RDC0870 from R&D Systems Prices $499.00 Sizes 10 µg Species Human

Human SLCO1B3 Gene ORF cDNA clone in cloning vector - HG13013-M from Sino Biological Species Human

Human SLCO1B3 Gene ORF cDNA clone expression plasmid, C-HA tag - HG13013-CY from Sino Biological Species Human

Human SLCO1B3 Gene ORF cDNA clone expression plasmid, N-Flag tag - HG13013-NF from Sino Biological Species Human

Human SLCO1B3 Gene cDNA Clone (full-length ORF Clone), expression ready, FLAG-tagged - HG13013-M-F from Sino Biological Species Human Accession BC141525

Human SLCO1B3 Gene cDNA Clone (full-length ORF Clone), expression ready, untagged - HG13013-M-N from Sino Biological Species Human Accession BC141525

Human SLCO1B3 Gene ORF cDNA clone expression plasmid, N-HA tag - HG13013-NY from Sino Biological Species Human

Human SLCO1B3 Gene ORF cDNA clone expression plasmid, N-Myc tag - HG13013-NM from Sino Biological Species Human

Human SLCO1B3 Gene ORF cDNA clone expression plasmid, C-Flag tag - HG13013-CF from Sino Biological Species Human

Human SLCO1B3 Gene ORF cDNA clone expression plasmid, N-His tag - HG13013-NH from Sino Biological Species Human

Human SLCO1B3 Gene ORF cDNA clone expression plasmid, C-Myc tag - HG13013-CM from Sino Biological Species Human

Human SLCO1B3 Gene ORF cDNA clone expression plasmid - HG13013-UT from Sino Biological Species Human

Human SLCO1B3 Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - HG13013-ACG from Sino Biological Species Human

Human SLCO1B3 Gene ORF cDNA clone expression plasmid, C-His tag - HG13013-CH from Sino Biological Species Human

Human SLCO1B3 ORF clone(NM_019844.3) - CDCH401248 from Creative biogene Species Human

Human SLCO1B3 ORF clone (BC141525) - CDCB160279 from Creative biogene Species Human

Human SLCO1B3 Gene ORF cDNA clone expression plasmid, C-OFPSpark tag - HG13013-ACR from Sino Biological Species Human

Human SLCO1B3 Gene ORF cDNA clone expression plasmid, N-GFPSpark tag - HG13013-ANG from Sino Biological Species Human

Search more