SLCO1B3

Gene Symbol SLCO1B3
Entrez Gene 28234
Alt Symbol HBLRR, LST-2, LST-3TM13, LST3, OATP-8, OATP1B3, OATP8, SLC21A8
Species Human
Gene Type protein-coding
Description solute carrier organic anion transporter family, member 1B3
Other Description liver-specific organic anion transporter 2|liver-specific organic anion transporter 3TM13|organic anion transporter 8|organic anion transporter LST-3c|organic anion-transporting polypeptide 8|solute carrier family 21 (organic anion transporter), member 8|solute carrier organic anion transporter family member 1B3
Swissprots E7EMT8 Q5JAR4 Q9NPD5
Accessions CAB97008 EAW96413 EAW96414 EAW96415 Q9NPD5 AB669023 AF187815 AAG43445 AJ251506 CAB96997 AK055874 BAG51590 AY342017 AAQ19672 BC022843 AAH22843 BC058006 BC070264 AAH70264 BC105597 AAI05598 BC141525 AAI41526 BG567966 BM968322 NM_019844 NP_062818
Function Mediates the Na(+)-independent uptake of organic anions such as 17-beta-glucuronosyl estradiol, taurocholate, triiodothyronine (T3), leukotriene C4, dehydroepiandrosterone sulfate (DHEAS), methotrexate and sulfobromophthalein (BSP). Involved in the clearance of bile acids and organic anions from the liver. {ECO:0000269|PubMed:22232210}.
Subcellular Location Basolateral cell membrane; Multi-pass membrane protein.
Tissue Specificity Highly expressed in liver, in particular at the basolateral membrane of hepatocytes near the central vein. Not detected in other tissues. Highly expressed in some cancer cell lines derived from colon, pancreas, liver and gall bladder.
Top Pathways Bile secretion

OATP8 (H-52) - sc-98981 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
OATP8 (H-52): sc-98981. Western blot analysis of OATP8 expression in HeLa whole cell lysate.

OATP8 (C-14) - sc-47273 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

OATP8 (D-16) - sc-47274 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

OATP8 (T-14) - sc-47276 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-SLCO1B3 antibody - C-terminal - ab139120 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-SLCO1B3 antibody - C-terminal (ab139120) at 1/100 dilution + NCI-H460 cell line lysates at 35 µgdeveloped using the ECL technique

Anti-SLCO1B3 / OATP8 Antibody (aa151-161) - LS-C112893 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

Anti-SLCO1B3 / OATP8 Antibody (N-Terminus, clone mMDQ) - LS-C193437 from LifeSpan Bioscience

Prices $415.00
Sizes 5 ml
Host Mouse
Clonality Monoclonal
Clone mMDQ

Anti-SLCO1B3 / OATP8 Antibody (aa639-668, APC) - LS-C240978 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SLCO1B3 / OATP8 Antibody (aa639-668, Biotin) - LS-C240980 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SLCO1B3 / OATP8 Antibody (aa639-668, Azide-free, HRP) - LS-C248197 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SLCO1B3 / OATP8 Antibody (aa639-668, FITC) - LS-C240981 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SLCO1B3 / OATP8 Antibody (aa639-668, AP) - LS-C240977 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SLCO1B3 / OATP8 Antibody (aa639-668, PE) - LS-C240982 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SLCO1B3 / OATP8 Antibody (aa639-668) - LS-C330156 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

OATP1B3/SLCO1B3/OATP8 Antibody (1F6.1B1) - NBP2-36493 from Novus Biologicals

Prices $99.00, $229.00
Sizes 25 µg, 100 µg
Host Mouse
Clonality Monoclonal
Clone 1F6.1B1

OATP1B3/SLCO1B3/OATP8 Antibody (1E6.2F9) - NBP2-36492 from Novus Biologicals

Prices $99.00, $229.00
Sizes 25 µg, 100 µg
Host Mouse
Clonality Monoclonal
Clone 1E6.2F9
Immunohistochemistry-Paraffin: OATP1B3/SLCO1B3/OATP8 Antibody (1E6.2F9) [NBP2-36492] - IHC analysis of formalin-fixed paraffin-embedded tissue section of human renal cell carcinoma using mouse monoclonal OATP1B3/SLCO1B3/OATP8 antibody (1E6.2F9) at 5 ug/ml concentration.

OATP1B3/SLCO1B3/OATP8 Antibody - NBP1-80980 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunocytochemistry/Immunofluorescence: OATP1B3/SLCO1B3/OATP8 Antibody [NBP1-80980] - Staining of human cell line A-431 shows positivity in cytoplasm.

OATP1B3/SLCO1B3/OATP8 Antibody (1F6.1B1) [DyLight 650] - NBP2-36493C from Novus Biologicals

Prices $349.00
Sizes 100 tests
Host Mouse
Clonality Monoclonal
Clone 1F6.1B1

OATP1B3/SLCO1B3/OATP8 Antibody (1F6.1B1) [DyLight 550] - NBP2-36493R from Novus Biologicals

Prices $349.00
Sizes 100 tests
Host Mouse
Clonality Monoclonal
Clone 1F6.1B1

OATP1B3/SLCO1B3/OATP8 Antibody (1F6.1B1) [DyLight 488] - NBP2-36493G from Novus Biologicals

Prices $349.00
Sizes 100 tests
Host Mouse
Clonality Monoclonal
Clone 1F6.1B1

OATP1B3/SLCO1B3/OATP8 Antibody (1F6.1B1) [DyLight 405LS] - NBP2-36493V3 from Novus Biologicals

Prices $349.00
Sizes 100 tests
Host Mouse
Clonality Monoclonal
Clone 1F6.1B1

OATP1B3/SLCO1B3/OATP8 Antibody (1F6.1B1) [DyLight 405] - NBP2-36493V from Novus Biologicals

Prices $349.00
Sizes 100 tests
Host Mouse
Clonality Monoclonal
Clone 1F6.1B1

OATP1B3/SLCO1B3/OATP8 Antibody (1F6.1B1) [DyLight 350] - NBP2-36493UV from Novus Biologicals

Prices $349.00
Sizes 100 tests
Host Mouse
Clonality Monoclonal
Clone 1F6.1B1

OATP1B3/SLCO1B3/OATP8 Antibody (1F6.1B1) [Biotin] - NBP2-36493B from Novus Biologicals

Prices $349.00
Sizes 100 tests
Host Mouse
Clonality Monoclonal
Clone 1F6.1B1

OATP1B3/SLCO1B3/OATP8 Antibody (1F6.1B1) [Allophycocyanin] - NBP2-36493APC from Novus Biologicals

Prices $349.00
Sizes 100 tests
Host Mouse
Clonality Monoclonal
Clone 1F6.1B1
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