SKAP1

Gene Symbol	SKAP1
Entrez Gene	8631
Alt Symbol	HEL-S-81p, SCAP1, SKAP55
Species	Human
Gene Type	protein-coding
Description	src kinase associated phosphoprotein 1
Other Description	SKAP-55|epididymis secretory sperm binding protein Li 81p|pp55|src family associated phosphoprotein 1|src family-associated phosphoprotein 1|src kinase-associated phosphoprotein 1|src kinase-associated phosphoprotein of 55 kDa
Swissprots	Q86WV1 D3DTV1 O15268
Accessions	EAW94747 EAW94748 EAW94749 EAW94750 EAW94751 Q86WV1 AK290818 BAF83507 BC039040 BC047870 AAH47870 DR007155 EU668346 ACF94499 Y11215 CAA72101 XM_005257755 XP_005257812 XM_011525408 XP_011523710 XM_011525409 XP_011523711 XM_011525410 XP_011523712 XM_011525411 XP_011523713 XM_011525412 XP_011523714 XM_011525413 XP_011523715 XM_011525414 XP_011523716 XM_011525415 XP_011523717 NM_001075099 NP_001068567 NM_003726 NP_003717
Function	Positively regulates T-cell receptor signaling by enhancing the MAP kinase pathway. Required for optimal conjugation between T-cells and antigen-presenting cells by promoting the clustering of integrin ITGAL on the surface of T-cells. May be involved in high affinity immunoglobulin epsilon receptor signaling in mast cells. {ECO:0000269|PubMed:10856234, ECO:0000269|PubMed:11909961, ECO:0000269|PubMed:12652296, ECO:0000269|PubMed:15939789, ECO:0000269|PubMed:16980616}.
Subcellular Location	Cytoplasm. Nucleus. Cell membrane. Note=Upon T-cell stimulation, translocates to lipid rafts at the cell membrane.
Tissue Specificity	Highly expressed in thymocytes and peripheral blood lymphocytes. Also expressed in spleen cells and testis. Present in T-cells (at protein level). {ECO:0000269|PubMed:9195899}.
Top Pathways	Rap1 signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human SKAP55 full length protein - ab160123 from Abcam Category Protein Source Wheat germ Species Human

Human SKAP55 protein fragment - ab160124 from Abcam Category Protein Source Wheat germ Species Human

SKAP1 / SCAP1 Antibody Blocking Peptide - LS-E6185 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

SKAP1 / SCAP1 Antibody Blocking Peptide - LS-E16777 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human SKAP55 Protein - H00008631-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human SKAP55 Protein - H00008631-P01 from Novus Biologicals Category Protein Prices $250.00 Sizes 2 µg Source Wheat Germ Species Human

SKAP1-Antibody-C-term-Blocking-Peptide - BP18824b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Human SKAP1 protein - orb246583 from Biorbyt Category Protein Prices $340.00, $629.00, $1,003.00, $1,556.00 Sizes 50 μg, 200 μg, 500 μg, 1 mg Species Human

SKAP1 Blocking Peptide - 33R-7848 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

SCAP1 / SKAP55 - H00008631-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

SCAP1 / SKAP55 - H00008631-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

SCAP1 / SKAP55 - H00008631-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

SCAP1 / SKAP55 - H00008631-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

SKAP55,SKAP1 fusion protein - Ag6333 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

SKAP55,SKAP1 fusion protein - Ag6467 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

Recombinant Human SKAP1, GST-tagged - SKAP1-2687H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Human Src kinase-associated phosphoprotein 1(SKAP1) - CSB-YP769799HU CSB-BP769799HU CSB-MP769799HU from Cusabio Category Protein Source Yeast or Baculovirus or Mammalian cell Species Human

Recombinant human Src kinase-associated phosphoprotein 1 - CSB-EP769799HU from Cusabio Category Protein Source E.coli Species Human

SKAP55 Protein - abx164906 from Abbexa Category Protein Species Human, Mouse, Rat

SCAP1 / SKAP55 (transcript variant 2) - TP308493 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

SCAP1 / SKAP55 (transcript variant 1) - TP317083 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

Recombinant Src Kinase Associated Phosphoprotein 1 (SKAP1) - RPC846Mu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Mouse

Recombinant Src Kinase Associated Phosphoprotein 1 (SKAP1) - RPC846Ra01 from Uscn Life Science Inc. Category Protein Source E.coli Species Rat

SKAP55 Recombinant Protein Antigen - NBP1-87836PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

SKAP1 Peptide, Human - M34GP14285H from Creative Peptides Category Peptide Source Synthetic. Species Human

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