LAMTOR4

Gene Symbol LAMTOR4
Entrez Gene 389541
Alt Symbol C7orf59
Species Human
Gene Type protein-coding
Description late endosomal/lysosomal adaptor, MAPK and MTOR activator 4
Other Description UPF0539 protein C7orf59|late endosomal/lysosomal adaptor and MAPK and MTOR activator 4|ragulator complex protein LAMTOR4
Swissprots Q0VGL1
Accessions CAD61554 EAW76584 EAW76585 Q0VGL1 BC063401 AAH63401 BC105609 AAI05610 BC130553 AAI30554 BC130559 AAI30560 BE733059 BG715626 HQ258033 ADR82787 XM_011516198 XP_011514500 XM_011516199 XP_011514501 NM_001008395 NP_001008396
Function As part of the Ragulator complex it is involved in amino acid sensing and activation of mTORC1, a signaling complex promoting cell growth in response to growth factors, energy levels, and amino acids. Activated by amino acids through a mechanism involving the lysosomal V-ATPase, the Ragulator functions as a guanine nucleotide exchange factor activating the small GTPases Rag. Activated Ragulator and Rag GTPases function as a scaffold recruiting mTORC1 to lysosomes where it is in turn activated. {ECO:0000269|PubMed:22980980}.
Subcellular Location Lysosome {ECO:0000269|PubMed:22980980}.

LAMTOR4/C7orf59 (D4P6O) Rabbit mAb - 13140 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Monoclonal
Clone D4P6O
Western blot analysis of extracts from various cell lines using LAMTOR4/C7orf59 (D4P6O) Rabbit mAb.

LAMTOR4/C7orf59 (D6A4V) Rabbit mAb - 12284 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Monoclonal
Clone D6A4V
Western blot analysis of extracts from various cell lines using LAMTOR4/C7orf59 (D6A4V) Rabbit mAb.

LAMTOR4 (C-13) - sc-243295 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

LAMTOR4 (N-18) - sc-243293 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-C7orf59 antibody - ab121645 from Abcam

Prices $443.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunofluorescent staining of Human cell line U-251MG shows positivity in golgi apparatus. Recommended concentration of ab121645 1-4 µg/ml. Cells treated with PFA/Triton X-100.

Anti-C7orf59 antibody - ab128306 from Abcam

Prices $359.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-C7orf59 antibody (ab128306) at 1 µg/ml + Mouse heart lysate at 10 µg

C7orf59 Antibody - NBP1-90936 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: C7orf59 Antibody [NBP1-90936] - Lane 1: NIH-3T3 cell lysate (Mouse embryonic fibroblast cells). Lane 2: NBT-II cell lysate (Rat Wistar bladder tumor cells).

C7orf59 Polyclonal Antibody - bs-15275R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Thrap3 Polyclonal Antibody - bs-6991R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Formalin-fixed and paraffin embedded rat brain labeled with Anti-Thrap3/TRAP150 Polyclonal Antibody, Unconjugated (bs-6991R) at 1:200 followed by conjugation to the secondary antibody and DAB staining

Anti-LAMTOR4 antibody produced in rabbit - HPA020998 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-C7orf59: <B>Cat. No. HPA020998</B>: Immunohistochemical staining of human small intestine shows strong granular positivity accentuated in the luminal part of the cells.

C7orf59 Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated - bs-15275R-A350 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

C7orf59 Polyclonal Antibody, ALEXA FLUOR® 488 Conjugated - bs-15275R-A488 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

C7orf59 Polyclonal Antibody, ALEXA FLUOR® 555 Conjugated - bs-15275R-A555 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

C7orf59 Polyclonal Antibody, ALEXA FLUOR® 647 Conjugated - bs-15275R-A647 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

C7orf59 Polyclonal Antibody, Cy3 Conjugated - bs-15275R-Cy3 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

C7orf59 Polyclonal Antibody, Cy5 Conjugated - bs-15275R-Cy5 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

C7orf59 Polyclonal Antibody, Cy5.5 Conjugated - bs-15275R-Cy5.5 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

C7orf59 Polyclonal Antibody, Cy7 Conjugated - bs-15275R-Cy7 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

C7orf59 Polyclonal Antibody, FITC Conjugated - bs-15275R-FITC from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

C7orf59 Polyclonal Antibody, Biotin Conjugated - bs-15275R-Biotin from Bioss

Prices $349.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

C7orf59 Polyclonal Antibody, HRP Conjugated - bs-15275R-HRP from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-LAMTOR4 (aa 1-99) polyclonal antibody - DPABH-19554 from Creative Diagnostics

Host Rabbit
Clonality Polyclonal

Thrap3 Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated - bs-6991R-A350 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Thrap3 Polyclonal Antibody, ALEXA FLUOR® 488 Conjugated - bs-6991R-A488 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Thrap3 Polyclonal Antibody, ALEXA FLUOR® 555 Conjugated - bs-6991R-A555 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Search more