LAMTOR4

Gene Symbol	LAMTOR4
Entrez Gene	389541
Alt Symbol	C7orf59
Species	Human
Gene Type	protein-coding
Description	late endosomal/lysosomal adaptor, MAPK and MTOR activator 4
Other Description	UPF0539 protein C7orf59|late endosomal/lysosomal adaptor and MAPK and MTOR activator 4|ragulator complex protein LAMTOR4
Swissprots	Q0VGL1
Accessions	CAD61554 EAW76584 EAW76585 Q0VGL1 BC063401 AAH63401 BC105609 AAI05610 BC130553 AAI30554 BC130559 AAI30560 BE733059 BG715626 HQ258033 ADR82787 XM_011516198 XP_011514500 XM_011516199 XP_011514501 NM_001008395 NP_001008396
Function	As part of the Ragulator complex it is involved in amino acid sensing and activation of mTORC1, a signaling complex promoting cell growth in response to growth factors, energy levels, and amino acids. Activated by amino acids through a mechanism involving the lysosomal V-ATPase, the Ragulator functions as a guanine nucleotide exchange factor activating the small GTPases Rag. Activated Ragulator and Rag GTPases function as a scaffold recruiting mTORC1 to lysosomes where it is in turn activated. {ECO:0000269|PubMed:22980980}.
Subcellular Location	Lysosome {ECO:0000269|PubMed:22980980}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human C7orf59 full length protein - ab183247 from Abcam Category Protein Prices $301.00 Sizes 20 µg Source E. coli Species Human

LAMTOR4 Antibody Blocking Peptide - LS-E19579 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

LAMTOR4 protein (His tag) - 80R-3924 from Fitzgerald Category Protein Prices $275.00 Sizes 20 µg Source E.coli

LAMTOR4 (1-99, His-tag) - AR51611PU-N from Acris Antibodies Category Protein Prices $790.00 Sizes 100 µg Source E. coli Species Human

LAMTOR4 (1-99, His-tag) - AR51611PU-S from Acris Antibodies Category Protein Prices $340.00 Sizes 20 µg Source E. coli Species Human

Recombinant Human LAMTOR4 - LAMTOR4-1381H from Creative Biomart Category Protein Source Mammalian Cells Species Human

Recombinant Human UPF0539 protein C7orf59(C7orf59) - CSB-YP613151HU CSB-EP613151HU CSB-BP613151HU CSB-MP613151HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

LAMTOR4, 1-99aa, Human, His tag, E.coli - ATGP2791 from ATGen Category Protein Prices $80.00, $240.00, $720.00 Sizes 4 µg, 20 µg, 100 µg Species Human

LAMTOR4 Protein (Recombinant) - abx263435 from Abbexa Category Protein

Chromosome 7 open reading frame 59 (C7orf59) - TP309099 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

C7orf59 Recombinant Protein Antigen - NBP1-90936PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

LAMTOR4 Peptide, Human - M34GP08538H from Creative Peptides Category Peptide Source Synthetic. Species Human

Recombinant Human C7orf59 Protein - NBP2-51803 from Novus Biologicals Category Protein Prices $259.00, $759.00 Sizes 20 µg, 100 µg Source E.coli Species Human

LAMTOR4 - PAT-82790-1 from Nordic BioSite Category Protein Species Human

LAMTOR4 - PAT-82790-2 from Nordic BioSite Category Protein Species Human

LAMTOR4, Human Recombinant - 228-22172-1 from RayBiotech Category Protein Species Human

LAMTOR4, Recombinant Protein - MBS140760 from MyBioSource Category Protein Prices $140.00, $205.00, $1,220.00 Sizes 2 µg, 10 µg, 100 µg Source E Coli

LAMTOR4, Recombinant Protein - MBS206046 from MyBioSource Category Protein Prices $310.00, $720.00 Sizes 20 µg, 100 µg Source E Coli Species Human

Recombinant Human LAMTOR4 Protein, GST-Tagged - LAMTOR4-0152H from Creative Biomart Category Protein Source Wheat Germ Species Human

Recombinant Human LAMTOR4 Protein, MYC/DDK-tagged - LAMTOR4-161H from Creative Biomart Category Protein Source HEK293 Species Human

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