LAMTOR4

Gene Symbol LAMTOR4
Entrez Gene 389541
Alt Symbol C7orf59
Species Human
Gene Type protein-coding
Description late endosomal/lysosomal adaptor, MAPK and MTOR activator 4
Other Description UPF0539 protein C7orf59|late endosomal/lysosomal adaptor and MAPK and MTOR activator 4|ragulator complex protein LAMTOR4
Swissprots Q0VGL1
Accessions CAD61554 EAW76584 EAW76585 Q0VGL1 BC063401 AAH63401 BC105609 AAI05610 BC130553 AAI30554 BC130559 AAI30560 BE733059 BG715626 HQ258033 ADR82787 XM_011516198 XP_011514500 XM_011516199 XP_011514501 NM_001008395 NP_001008396
Function As part of the Ragulator complex it is involved in amino acid sensing and activation of mTORC1, a signaling complex promoting cell growth in response to growth factors, energy levels, and amino acids. Activated by amino acids through a mechanism involving the lysosomal V-ATPase, the Ragulator functions as a guanine nucleotide exchange factor activating the small GTPases Rag. Activated Ragulator and Rag GTPases function as a scaffold recruiting mTORC1 to lysosomes where it is in turn activated. {ECO:0000269|PubMed:22980980}.
Subcellular Location Lysosome {ECO:0000269|PubMed:22980980}.

chromosome 7 open reading frame 59, ELISA Kit - MBS9328600 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Human C7orf59 ELISA Kit - E009285 from Biobool

Category ELISA Kit

Human LAMTOR4 ELISA Kit - E088795 from Biobool

Category ELISA Kit
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