UBR1

Gene Symbol UBR1
Entrez Gene 197131
Alt Symbol JBS
Species Human
Gene Type protein-coding
Description ubiquitin protein ligase E3 component n-recognin 1
Other Description E3 ubiquitin-protein ligase UBR1|E3a ligase|N-recognin-1|ubiquitin ligase E3 alpha-I|ubiquitin-protein ligase E3-alpha|ubiquitin-protein ligase E3-alpha-1|ubiquitin-protein ligase E3-alpha-I
Swissprots Q8IWV7 Q68DN9 Q96JY4 O75492 Q8IWY6 Q14D45 O60708
Accessions CCQ43900 EAW92584 Q8IWV7 AF061556 AAC39845 AF525401 AAO14997 AK027803 BAB55380 AK054969 AK056441 AK127478 AK292516 BAF85205 AK302489 BAG63774 AY061886 AAL32103 BC113505 AAI13506 BC113507 AAI13508 BE873236 BX648400 CR749326 CAH18181 NM_174916 NP_777576
Function E3 ubiquitin-protein ligase which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. May be involved in pancreatic homeostasis. Binds leucine and is a negative regulator of the leucine-mTOR signaling pathway, thereby controlling cell growth. {ECO:0000269|PubMed:15548684, ECO:0000269|PubMed:16311597, ECO:0000269|PubMed:20298436, ECO:0000269|PubMed:20835242}.
Subcellular Location Cytoplasm, cytosol {ECO:0000269|PubMed:16311597}.
Tissue Specificity Broadly expressed, with highest levels in skeletal muscle, kidney and pancreas. Present in acinar cells of the pancreas (at protein level). {ECO:0000269|PubMed:15548684, ECO:0000269|PubMed:16311597, ECO:0000269|PubMed:9653112}.

Human UBR1 ELISA Kit (Sandwich ELISA) - LS-F12895 from LifeSpan Bioscience

Category ELISA Kit
Prices $600.00
Sizes 1 plate
Sensitivity 0.156
Range 0.156-10 ng/ml

E3 ubiquitin-protein ligase UBR1, UBR1, Human, ELISA Kit - E2362h from ARP American Research Products

Category ELISA Kit
Prices $596.00
Sizes 96 t
Range 0.156-10 ng/mL

ubiquitin protein ligase E3 component n-recognin 1, ELISA Kit - MBS9325968 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Ubiquitin Protein Ligase E3 Component N-Recognin 1 (UBR1), ELISA Kit - MBS2024968 from MyBioSource

Category ELISA Kit
Prices $410.00, $610.00, $830.00, $3,420.00, $6,200.00
Sizes 24 -strip-wells, 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
Sensitivity Typically less than 0.055ng/mL.
Range 0.156-10ng/mL

Ubiquitin Protein Ligase E3 Component N-Recognin 4, ELISA Kit - MBS052228 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Ubiquitin Protein Ligase E3 Component N-Recognin 4, ELISA Kit - MBS078342 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Ubiquitin Protein Ligase E3 Component N-Recognin 4, ELISA Kit - MBS070419 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Ubiquitin Protein Ligase E3 Component N-Recognin 4, ELISA Kit - MBS102685 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Ubiquitin Protein Ligase E3 Component N-Recognin 4, ELISA Kit - MBS068645 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Ubiquitin Protein Ligase E3 Component N-Recognin 4, ELISA Kit - MBS083493 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Ubiquitin Protein Ligase E3 Component N-Recognin 4, ELISA Kit - MBS078387 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Ubiquitin Protein Ligase E3 Component N-Recognin 4, ELISA Kit - MBS061237 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Ubiquitin Protein Ligase E3 Component N-Recognin 4, ELISA Kit - MBS089925 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Ubiquitin Protein Ligase E3 Component N-Recognin 4, ELISA Kit - MBS090190 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Ubiquitin Protein Ligase E3 Component N-Recognin 4, ELISA Kit - MBS055118 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Ubiquitin Protein Ligase E3 Component N-Recognin 4, ELISA Kit - MBS062554 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Ubiquitin Protein Ligase E3 Component N-Recognin 4, ELISA Kit - MBS089193 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Ubiquitin Protein Ligase E3 Component N-Recognin 4, ELISA Kit - MBS087415 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Ubiquitin Protein Ligase E3 Component N-Recognin 4, ELISA Kit - MBS077460 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Ubiquitin Protein Ligase E3 Component N-Recognin 4, ELISA Kit - MBS081307 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Ubiquitin Protein Ligase E3 Component N-Recognin 4, ELISA Kit - MBS068508 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Ubiquitin Protein Ligase E3 Component N-Recognin 4, ELISA Kit - MBS081822 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Ubiquitin Protein Ligase E3 Component N-Recognin 4, ELISA Kit - MBS071896 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Ubiquitin Protein Ligase E3 Component N-Recognin 4, ELISA Kit - MBS080371 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Ubiquitin Protein Ligase E3 Component N-Recognin 4, ELISA Kit - MBS074747 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
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