FBXL15

Gene Symbol	FBXL15
Entrez Gene	79176
Alt Symbol	FBXO37, Fbl15, JET, PSD
Species	Human
Gene Type	protein-coding
Description	F-box and leucine-rich repeat protein 15
Other Description	F-box only protein 37|F-box/LRR-repeat protein 15|pleckstrin and Sec7 domain protein
Swissprots	B1AKY0 Q5JWA5 Q0D2Q3 B1AKX8 Q9H469 B1AKY1 Q49AL7 A1L4J8 B1AKX9 C9JWA4
Accessions	EAW49699 Q9H469 AK122684 BC002912 AAH02912 BC036120 AAH36120 BC130566 AAI30567 BI914195 XM_005270149 XP_005270206 XM_005270150 XP_005270207 XM_005270151 XP_005270208 NM_024326 NP_077302
Function	Substrate recognition component of a SCF (SKP1-CUL1-F- box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of SMURF1, thereby acting as a positive regulator of the BMP signaling pathway. Required for dorsal/ventral pattern formation and bone mass maintenance. Also mediates ubiquitination of SMURF2 and WWP2. {ECO:0000269|PubMed:21572392}.
Subcellular Location	Cytoplasm {ECO:0000269|PubMed:21572392}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human PSD peptide - ab23135 from Abcam Category Peptide Species Human

FBXL15 Antibody Blocking Peptide - LS-E25010 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

FBXL15 Antibody Blocking Peptide - LS-E7776 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

FBXL15-Antibody-C-term-Blocking-peptide - BP5221b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

FBXL15 fusion protein - Ag16972 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

FBXL15 fusion protein - Ag14949 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

Recombinant Human FBXL15, His-tagged - FBXL15-12773H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Human F-box/LRR-repeat protein 15(FBXL15) - CSB-YP875670HU CSB-EP875670HU CSB-BP875670HU CSB-MP875670HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

FBXL15 Peptide, Human - M34GP05570H from Creative Peptides Category Peptide Source Synthetic. Species Human

PSD Peptide, Human - M34GP12556H from Creative Peptides Category Peptide Source Synthetic. Species Human

F-box/LRR-repeat protein 15 (FBXL15), Recombinant Protein - MBS1313817 from MyBioSource Category Protein Prices $1,055.00, $1,055.00, $1,285.00, $1,285.00, $1,645.00, $1,645.00, $2,110.00, $2,110.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

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