FBXL15

Gene Symbol FBXL15
Entrez Gene 79176
Alt Symbol FBXO37, Fbl15, JET, PSD
Species Human
Gene Type protein-coding
Description F-box and leucine-rich repeat protein 15
Other Description F-box only protein 37|F-box/LRR-repeat protein 15|pleckstrin and Sec7 domain protein
Swissprots B1AKY0 Q5JWA5 Q0D2Q3 B1AKX8 Q9H469 B1AKY1 Q49AL7 A1L4J8 B1AKX9 C9JWA4
Accessions EAW49699 Q9H469 AK122684 BC002912 AAH02912 BC036120 AAH36120 BC130566 AAI30567 BI914195 XM_005270149 XP_005270206 XM_005270150 XP_005270207 XM_005270151 XP_005270208 NM_024326 NP_077302
Function Substrate recognition component of a SCF (SKP1-CUL1-F- box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of SMURF1, thereby acting as a positive regulator of the BMP signaling pathway. Required for dorsal/ventral pattern formation and bone mass maintenance. Also mediates ubiquitination of SMURF2 and WWP2. {ECO:0000269|PubMed:21572392}.
Subcellular Location Cytoplasm {ECO:0000269|PubMed:21572392}.

FBL15 (C-18) - sc-242797 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
FBL15 (C-18): sc-242797. Western blot analysis of FBL15 expression in MDA-MB-435S whole cell lysate.

Anti-FBXL15 antibody - ab103719 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
ab103719 stained HCT116 cells. The cells were 4% formaldehyde fixed for 10 minutes at room temperature and then incubated in 1%BSA / 10% normal goat serum / 0.3M glycine in 0.1% PBS-Tween for 1hour at room temperature to permeabilise the cells and block non-specific protein-protein interactions. The cells were then incubated with the antibody (ab103719 at 5µg/ml) overnight at +4°C. The secondary antibody (pseudo-colored green) was ab150081 used at a 1/1000 dilution for 1hour at room temperature. Alexa Fluor® 594 WGA was used to label plasma membranes (pseudo-colored red) at a 1/200 dilution for 1hour at room temperature. DAPI was used to stain the cell nuclei (pseudo-colored blue) at a concentration of 1.43µM for 1hour at room temperature.

Anti-FBXL15 antibody - N-terminal - ab178055 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-FBXL15 antibody - N-terminal (ab178055) at 1 µg/ml + Human fetal lung tissue lysate at 10 µg

Anti-FBXL15 Antibody (aa252-280, AP) - LS-C207021 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-FBXL15 Antibody (aa252-280, APC) - LS-C207022 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-FBXL15 Antibody (aa252-280, Biotin) - LS-C207023 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-FBXL15 Antibody (aa252-280, FITC) - LS-C207024 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-FBXL15 Antibody (aa252-280, PE) - LS-C207027 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-FBXL15 Antibody (aa252-280, Azide-free, HRP) - LS-C207026 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-FBXL15 Antibody (N-Terminus) - LS-C187018 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot of Fetal Lung. FBXL15 antibody dilution 1.0 ug/ml.

Anti-FBXL15 Antibody (aa260-290) - LS-C321308 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-FBXL15 Antibody (aa252-280) - LS-C166072 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
FBXL15 Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human breast carcinoma followed by peroxidase-conjugated secondary antibody and DAB staining.

Rabbit Anti-FBXL15 Polyclonal Antibody - bs-8475R from Bioss

Prices $245.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

ANTI-FBXL15 (C-TERM) antibody produced in rabbit - SAB1301478 from Sigma-Aldrich

Prices $326.50
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>FBXL15 (C-term): <B>Cat. No. SAB1301478</B>: FBXL15 in Human breast carcinoma tissue with FBXL15 antibody (C-term) at 5 μg/mL.

FBXL15 Antibody - N-terminal region (ARP70412_P050) - ARP70412_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

FBXL15 Antibody - C-terminal region (OAAB02638) - OAAB02638 from Aviva Systems Biology

Prices $289.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal

FBXL15-Antibody-C-term - AP5221b from Abgent, a WuXi AppTec company

Prices $99.00, $295.00
Sizes 80 µl, 400 µl
Host Rabbit
Clonality Polyclonal
FBXL15 Antibody (C-term) (Cat. #AP5221b) immunohistochemistry analysis in formalin fixed and paraffin embedded human breast carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the FBXL15 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.

Anti -FBXL15, CT (FBXL15, FBXO37, F-box/LRR-repeat protein 15, F-box only protein 37) - 035541 from USBiological Life Science

Host Rabbit
Clonality Polyclonal

FBXL15 antibody - 20895-1-AP from Acris Antibodies

Prices $270.00
Sizes 150 µl
Host Rabbit
Clonality Polyclonal
MDA-MB-453s cells were subjected to SDS PAGE followed by western blot with 20895-1-AP( FBXL15 Antibody) at dilution of 1:300
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