Gene Symbol | PON3 |
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Entrez Gene | 5446 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | paraoxonase 3 |
Other Description | arylesterase 3|paraoxanase-3|serum paraoxonase/lactonase 3 |
Swissprots | Q8IX97 O75855 Q9BZH9 Q6IRU9 A4D1H8 Q15166 O76060 |
Accessions | AAV50000 CBX51401 EAL24132 EAW76768 EAW76770 Q15166 AA860930 AF320003 AAK07629 AF329433 AAO15365 AK096114 AK304282 BAG65142 AV655538 BC020908 BC070374 AAH70374 CD014095 CD014097 CD014100 CD014102 HQ447597 ADQ32083 L48516 AAC41996 NM_000940 NP_000931 |
Function | Has low activity towards the organophosphate paraxon and aromatic carboxylic acid esters. Rapidly hydrolyzes lactones such as statin prodrugs (e.g. lovastatin). Hydrolyzes aromatic lactones and 5- or 6-member ring lactones with aliphatic substituents but not simple lactones or those with polar substituents. {ECO:0000269|PubMed:15772423}. |
Subcellular Location | Secreted, extracellular space {ECO:0000250}. |
PON3 (C-19) - sc-21154 from Santa Cruz Biotechnology
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PON3 (N-20) - sc-21152 from Santa Cruz Biotechnology
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Anti-PON3 antibody - ab42322 from Abcam
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Anti-PON3 antibody - ab157486 from Abcam
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Anti-PON3 antibody - ab172100 from Abcam
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Anti-PON3 antibody [5G11] - ab71994 from Abcam
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Anti-PON3 antibody [EPR2902(2)] - ab108964 from Abcam
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Anti-PON3 antibody [EPR2903(2)] - ab109258 from Abcam
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Anti-PON3 antibody - Aminoterminal end - ab93140 from Abcam
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Anti-PON3 Antibody (clone 5G11) IHC-plus⢠- LS-B7136 from LifeSpan Bioscience
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Anti-PON3 Antibody (aa30-319, clone 5C3) - LS-C340256 from LifeSpan Bioscience
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Anti-PON3 Antibody (aa10-38) - LS-C163865 from LifeSpan Bioscience
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Anti-PON3 Antibody (C-Terminus) IHC-plus⢠- LS-B6628 from LifeSpan Bioscience
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Anti-PON3 Antibody (aa1-354) - LS-C131217 from LifeSpan Bioscience
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Anti-PON3 Antibody (aa30-354) - LS-C38071 from LifeSpan Bioscience
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Anti-PON3 Antibody (aa10-38, AP) - LS-C280552 from LifeSpan Bioscience
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Anti-PON3 Antibody (aa10-38, Biotin) - LS-C280553 from LifeSpan Bioscience
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Anti-PON3 Antibody (aa10-38, APC) - LS-C280554 from LifeSpan Bioscience
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Anti-PON3 Antibody (Internal, clone EPR2902(2)) - LS-C138069 from LifeSpan Bioscience
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Anti-PON3 Antibody (aa143-192) - LS-C110654 from LifeSpan Bioscience
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Anti-PON3 Antibody (aa10-38, FITC) - LS-C280555 from LifeSpan Bioscience
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Anti-PON3 Antibody (aa10-38, Azide-free, HRP) - LS-C280556 from LifeSpan Bioscience
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Anti-PON3 Antibody (aa10-38, PE) - LS-C280557 from LifeSpan Bioscience
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Anti-PON3 Antibody (aa136-354) - LS-C311881 from LifeSpan Bioscience
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Anti-PON3 Antibody (aa17-46) - LS-C328148 from LifeSpan Bioscience
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