Gene Symbol | PON3 |
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Entrez Gene | 5446 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | paraoxonase 3 |
Other Description | arylesterase 3|paraoxanase-3|serum paraoxonase/lactonase 3 |
Swissprots | Q8IX97 O75855 Q9BZH9 Q6IRU9 A4D1H8 Q15166 O76060 |
Accessions | AAV50000 CBX51401 EAL24132 EAW76768 EAW76770 Q15166 AA860930 AF320003 AAK07629 AF329433 AAO15365 AK096114 AK304282 BAG65142 AV655538 BC020908 BC070374 AAH70374 CD014095 CD014097 CD014100 CD014102 HQ447597 ADQ32083 L48516 AAC41996 NM_000940 NP_000931 |
Function | Has low activity towards the organophosphate paraxon and aromatic carboxylic acid esters. Rapidly hydrolyzes lactones such as statin prodrugs (e.g. lovastatin). Hydrolyzes aromatic lactones and 5- or 6-member ring lactones with aliphatic substituents but not simple lactones or those with polar substituents. {ECO:0000269|PubMed:15772423}. |
Subcellular Location | Secreted, extracellular space {ECO:0000250}. |
PON3 293T Cell Transient Overexpression Lysate(Denatured) - H00005446-T01 from Acris Antibodies
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PON3 overexpression lysate - LY400339 from Acris Antibodies
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PON3 293 Cell Lysate - 400370 from ABBIOTEC
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PON3 Overexpression Lysate (Denatured) - H00005446-T01 from Novus Biologicals
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PON3 Overexpression Lysate (Native) - NBL1-14606 from Novus Biologicals
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PON3 Over-expression Lysate Product - GWB-D19502 from Genway Biotech
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Human PON3 / Paraoxonase 3 (50 Ser/Asn) Insect Cell Lysate (WB positive control) - 13063-H07BL-300 from Sino Biological
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Human PON3 Baculovirus-Insect Cells Transfected Lysate Baculovirus-Insect Cells Transfected Lysate (positive control) (denatured) - orb175148 from Biorbyt
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Panoply™ Human PON3 Knockdown Stable Cell Line - CSC-DC012127 from Creative biogene
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