Gene Symbol | PON3 |
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Entrez Gene | 5446 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | paraoxonase 3 |
Other Description | arylesterase 3|paraoxanase-3|serum paraoxonase/lactonase 3 |
Swissprots | Q8IX97 O75855 Q9BZH9 Q6IRU9 A4D1H8 Q15166 O76060 |
Accessions | AAV50000 CBX51401 EAL24132 EAW76768 EAW76770 Q15166 AA860930 AF320003 AAK07629 AF329433 AAO15365 AK096114 AK304282 BAG65142 AV655538 BC020908 BC070374 AAH70374 CD014095 CD014097 CD014100 CD014102 HQ447597 ADQ32083 L48516 AAC41996 NM_000940 NP_000931 |
Function | Has low activity towards the organophosphate paraxon and aromatic carboxylic acid esters. Rapidly hydrolyzes lactones such as statin prodrugs (e.g. lovastatin). Hydrolyzes aromatic lactones and 5- or 6-member ring lactones with aliphatic substituents but not simple lactones or those with polar substituents. {ECO:0000269|PubMed:15772423}. |
Subcellular Location | Secreted, extracellular space {ECO:0000250}. |
Human PON3 full length protein - ab132479 from Abcam
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Human PON3 peptide - ab197546 from Abcam
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Human PON3 peptide - ab42320 from Abcam
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Human PON3 peptide - ab42321 from Abcam
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PON3 Antibody Blocking Peptide - LS-E9665 from LifeSpan Bioscience
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PON3 Antibody Blocking Peptide - LS-E15389 from LifeSpan Bioscience
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PON3 Antibody Blocking Peptide - LS-E15390 from LifeSpan Bioscience
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Recombinant Human PON3 Protein - H00005446-P01 from Novus Biologicals
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PON3-Antibody-N-term-Blocking-Peptide - BP8595a from Abgent, a WuXi AppTec company
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Human PON3 protein (His Tag) - orb139504 from Biorbyt
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PON3 Blocking Peptide - 33R-7223 from Fitzgerald
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PON3 Blocking Peptide - 33R-2947 from Fitzgerald
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PON3 - H00005446-P01-10 from Acris Antibodies
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PON3 - H00005446-P01-25 from Acris Antibodies
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Recombinant Human PON3, His-tagged - PON3-27H from Creative Biomart
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Recombinant Paraoxonase 3 (PON3) - RPD178Hu01 from Uscn Life Science Inc.
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Human PON3 / Paraoxonase 3 Protein (50 Ser/Asn, His Tag) - 13063-H07B-20 from Sino Biological
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Recombinant Paraoxonase 3 (PON3) - RPD178Hu01 from Cloud-clone
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Recombinant Human Serum paraoxonase/lactonase 3(PON3) - CSB-YP614883HU CSB-EP614883HU CSB-BP614883HU CSB-MP614883HU from Cusabio
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Paraoxonase 3 Protein (Recombinant) - abx166722 from Abbexa
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Paraoxonase 3, Recombinant Protein - MBS2030563 from MyBioSource
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Recombinant Human PON3 / Paraoxonase 3 Protein (50 Ser/Asn, His tag) - PKSH030748 from Elabscience
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PON3 Recombinant Protein Antigen - NBP1-86074PEP from Novus Biologicals
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PON3 Peptide, Human - M34GP12127H from Creative Peptides
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Recombinant Paraoxonase 3 (PON3) - RPU52214 from Biomatik
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