PYHIN1

Gene Symbol	PYHIN1
Entrez Gene	149628
Alt Symbol	IFIX
Species	Human
Gene Type	protein-coding
Description	pyrin and HIN domain family, member 1
Other Description	interferon-inducible protein X|pyrin and HIN domain-containing protein 1
Swissprots	Q6K0P8 Q6K0P9 Q8WW65 Q6K0P7 Q5T3W6 Q6K0P6
Accessions	EAW52805 Q6K0P9 AK024890 AK308350 AW518129 AY185344 AAO67506 AY185345 AAO67507 AY185346 AAO67508 AY185347 AAO67509 BC020822 AAH20822 BC073133 BC090944 AAH90944 BC114470 BC139741 AAI39742 DB126431 DB188734 XM_005244930 XP_005244987 XM_011509242 XP_011507544 XM_011509243 XP_011507545 NM_152501 NP_689714 NM_198928 NP_945146 NM_198929 NP_945147 NM_198930 NP_945148
Function	Major mediator of the tumor suppressor activity of IFN in breast cancer cells. Promotes ubiquitination and subsequent degradation of MDM2, which leads to p53/TP53 stabilization. Promotes ubiquitination and subsequent degradation of HDAC1, which in turn enhances maspin expression, and impairs invasive activity of cancer cells. {ECO:0000269|PubMed:16479015, ECO:0000269|PubMed:18247378}.
Subcellular Location	Isoform 5: Nucleus. Nucleus speckle.
Tissue Specificity	Expressed in spleen, lymph node and peripheral blood leukocytes, and at lower levels in thymus, bone marrow and fetal liver. Down-regulated in breast tumors. {ECO:0000269|PubMed:15122330}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

IFIX (C-12) - sc-160441 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

IFIX (T-13) - sc-160443 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

Anti-PYHIN1 antibody - ab106144 from Abcam Prices $370.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-PYHIN1 antibody - ab106145 from Abcam Prices $359.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-IFIX / PYHIN1 Antibody (aa26-55, APC) - LS-C239648 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-IFIX / PYHIN1 Antibody (aa26-55, AP) - LS-C239649 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-IFIX / PYHIN1 Antibody (aa26-55, Biotin) - LS-C239650 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-IFIX / PYHIN1 Antibody (aa26-55, FITC) - LS-C239651 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-IFIX / PYHIN1 Antibody (aa26-55, PE) - LS-C239653 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-IFIX / PYHIN1 Antibody (aa26-55, Azide-free, HRP) - LS-C248593 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-IFIX / PYHIN1 Antibody (aa33-62) - LS-C324445 from LifeSpan Bioscience Prices $345.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-IFIX / PYHIN1 Antibody (N-Terminus) - LS-C82648 from LifeSpan Bioscience Prices $365.00 Sizes 50 µg Host Rabbit Clonality Polyclonal

Anti-IFIX / PYHIN1 Antibody (aa38-87) - LS-C82649 from LifeSpan Bioscience Prices $365.00 Sizes 50 µg Host Rabbit Clonality Polyclonal

Anti-IFIX / PYHIN1 Antibody (aa26-55) - LS-C162341 from LifeSpan Bioscience Prices $295.00 Sizes 400 µl Host Rabbit Clonality Polyclonal

PYHIN1 Antibody - NBP2-13835 from Novus Biologicals Prices $419.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

PYHIN1 Antibody - NBP1-79435 from Novus Biologicals Prices $329.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

PYHIN1 Antibody - NBP1-79436 from Novus Biologicals Prices $139.00, $329.00 Sizes 20 µl, 100 µl Host Rabbit Clonality Polyclonal

Anti-PYHIN1 antibody produced in rabbit - HPA051224 from Sigma-Aldrich Prices $429.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-PYHIN1 (ab1) antibody produced in rabbit - SAB2101923 from Sigma-Aldrich Prices $347.50 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-PYHIN1 (ab2) antibody produced in rabbit - SAB2101924 from Sigma-Aldrich Prices $347.50 Sizes 100 µl Host Rabbit Clonality Polyclonal

PYHIN1 antibody - N-terminal region (ARP50875_P050) - ARP50875_P050 from Aviva Systems Biology Prices $289.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

PYHIN1 antibody - N-terminal region (ARP50876_P050) - ARP50876_P050 from Aviva Systems Biology Prices $289.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

PYHIN1 Antibody - N-terminal region (OAAB02792) - OAAB02792 from Aviva Systems Biology Prices $289.00 Sizes 400 µl Host Rabbit Clonality Polyclonal

PYHIN1-Antibody-N-term - AP5376a from Abgent, a WuXi AppTec company Prices $99.00, $295.00 Sizes 80 µl, 400 µl Host Rabbit Clonality Polyclonal

PYHIN1 antibody - 70R-9019 from Fitzgerald Prices $345.00 Sizes 50 µg Host Rabbit Clonality Polyclonal

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