SLC39A4

Gene Symbol	SLC39A4
Entrez Gene	55630
Alt Symbol	AEZ, AWMS2, ZIP4
Species	Human
Gene Type	protein-coding
Description	solute carrier family 39 (zinc transporter), member 4
Other Description	zinc transporter ZIP4|zrt- and Irt-like protein 4
Swissprots	Q6P5W5 Q9NXC4 Q7L5S5 Q9H6T8
Accessions	CAH05339 CAH05356 EAW82101 EAW82102 EAW82103 EAW82104 EAW82105 Q6P5W5 AK000334 BAA91091 AK000489 BAA91200 AK000695 AK025537 BAB15164 AK056900 AK290563 BAF83252 BC001688 AAH01688 BC033807 BC062625 AAH62625 BE798833 BI765535 DA837547 DA915781 DC361959 XM_006716599 XP_006716662 XM_011517153 XP_011515455 NM_001280557 NP_001267486 NM_017767 NP_060237 NM_130849 NP_570901
Function	Plays an important role in cellular zinc homeostasis as a zinc transporter. Regulated in response to zinc availability (By similarity). {ECO:0000250}.
Subcellular Location	Cell membrane {ECO:0000269|PubMed:14612438}; Multi-pass membrane protein {ECO:0000269|PubMed:14612438}. Recycling endosome membrane {ECO:0000269|PubMed:14612438}; Multi- pass membrane protein {ECO:0000269|PubMed:14612438}. Note=Colocalized with TFRC in the recycling endosomes. Cycles between endosomal compartments and the plasma membrane in response to zinc availability.
Tissue Specificity	Highly expressed in kidney, small intestine, stomach, colon, jejunum and duodenum. {ECO:0000269|PubMed:12032886, ECO:0000269|PubMed:12068297}.
Top Pathways	Mineral absorption

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

SLC39A4 / ZIP4 Blocking Peptide - LS-E31041 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

SLC39A4 / ZIP4 Antibody Blocking Peptide - LS-E26890 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

SLC39A4-Antibody-C-term-Blocking-Peptide - BP9552a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

SLC39A4 blocking peptide - GTX47575-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human

ZIP4 Peptide - GTX84995-PEP from GeneTex Category Peptide Prices $149.00 Sizes 50 μg Species Human

SLC39A4 Protein Lysate (APL11091) - APL11091 from Aviva Systems Biology Category Protein Prices $219.00 Sizes 200 µg

SLC39A4 Blocking Peptide - 33R-1517 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

SLC39A4 Blocking Peptide - 33R-9661 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

SLC39A4 Blocking Peptide - 33R-7292 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

SLC39A4 Peptide - AC21-1724-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

Zinc transporter ZIP4 / SLC39A4 control peptide - AP26309CP-N from Acris Antibodies Category Peptide Prices $135.00 Sizes 50 µg

SLC39A4 Peptide - 42-046P from ProSci Category Peptide

SLC39A4 fusion protein - Ag14524 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

Zinc transporter ZIP4 / SLC39A4 (transcript variant 2) - TP309463 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

SLC39A4, Peptide - MBS426678 from MyBioSource Category Peptide Prices $175.00 Sizes 100 µg Species Human

SLC39A4 Protein Lysate - orb333649 from Biorbyt Category Protein Prices $400.00 Sizes 200 μg Species Human

SLC39A4 Peptide, Human - M34GP14565H from Creative Peptides Category Peptide Source Synthetic. Species Human

SLC39A4 Immunizing peptide - orb55063 from Biorbyt Category Peptide

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