SLC39A4

Gene Symbol SLC39A4
Entrez Gene 55630
Alt Symbol AEZ, AWMS2, ZIP4
Species Human
Gene Type protein-coding
Description solute carrier family 39 (zinc transporter), member 4
Other Description zinc transporter ZIP4|zrt- and Irt-like protein 4
Swissprots Q6P5W5 Q9NXC4 Q7L5S5 Q9H6T8
Accessions CAH05339 CAH05356 EAW82101 EAW82102 EAW82103 EAW82104 EAW82105 Q6P5W5 AK000334 BAA91091 AK000489 BAA91200 AK000695 AK025537 BAB15164 AK056900 AK290563 BAF83252 BC001688 AAH01688 BC033807 BC062625 AAH62625 BE798833 BI765535 DA837547 DA915781 DC361959 XM_006716599 XP_006716662 XM_011517153 XP_011515455 NM_001280557 NP_001267486 NM_017767 NP_060237 NM_130849 NP_570901
Function Plays an important role in cellular zinc homeostasis as a zinc transporter. Regulated in response to zinc availability (By similarity). {ECO:0000250}.
Subcellular Location Cell membrane {ECO:0000269|PubMed:14612438}; Multi-pass membrane protein {ECO:0000269|PubMed:14612438}. Recycling endosome membrane {ECO:0000269|PubMed:14612438}; Multi- pass membrane protein {ECO:0000269|PubMed:14612438}. Note=Colocalized with TFRC in the recycling endosomes. Cycles between endosomal compartments and the plasma membrane in response to zinc availability.
Tissue Specificity Highly expressed in kidney, small intestine, stomach, colon, jejunum and duodenum. {ECO:0000269|PubMed:12032886, ECO:0000269|PubMed:12068297}.
Top Pathways Mineral absorption

ZIP4 CRISPR/Cas9 KO Plasmid (h) - sc-412558 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

ZIP4 HDR Plasmid (h) - sc-412558-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ZIP4 Double Nickase Plasmid (h) - sc-412558-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ZIP4 Double Nickase Plasmid (h2) - sc-412558-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ZIP4 CRISPR Activation Plasmid (h) - sc-412558-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

ZIP4 CRISPR Activation Plasmid (h2) - sc-412558-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

ZIP4 Lentiviral Activation Particles (h) - sc-412558-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ZIP4 Lentiviral Activation Particles (h2) - sc-412558-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ZIP4 siRNA (h) - sc-77764 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

ZIP4 shRNA Plasmid (h) - sc-77764-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

ZIP4 shRNA (h) Lentiviral Particles - sc-77764-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

SLC39A4/ZIP4 RNAi - H00055630-R02 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

SLC39A4/ZIP4 RNAi - H00055630-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU133941 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN19622 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND19622 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

SLC39A4 siRNA (Human) - CRJ0789 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

SLC39A4 - MBS8220758 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human SLC39A4 (NM_017767.2) - SHH411148 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human SLC39A4(NM_130849.2) - SHL008202 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human SLC39A4(NM_017767.2) - SHL008272 from Creative biogene

Category siRNA
Species Reactivities Human

Human SLC39A4 siRNA - orb271290 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

SLC39A4 shRNA Plasmid (Human) - CHJ0789 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

SLC39A4 miRNA 3'UTR clone - MiUTR1H-09558 from Creative biogene

Species Reactivities Human

SLC39A4 miRNA 3'UTR clone - MiUTR1H-09559 from Creative biogene

Species Reactivities Human
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