TNFSF14

Gene Symbol	TNFSF14
Entrez Gene	8740
Alt Symbol	CD258, HVEML, LIGHT, LTg, TR2
Species	Human
Gene Type	protein-coding
Description	tumor necrosis factor (ligand) superfamily, member 14
Other Description	delta transmembrane LIGHT|herpes virus entry mediator ligand|herpesvirus entry mediator A|herpesvirus entry mediator ligand|herpesvirus entry mediator-ligand|ligand for herpesvirus entry mediator|tumor necrosis factor ligand superfamily member 14|tumor necrosis factor receptor-like 2|tumor necrosis factor superfamily member LIGHT
Swissprots	A8K7M2 O43557 Q6FHA1 O75476 Q96LD2 C9J5H4 Q8WVF8
Accessions	AAN34658 CAL00173 CBX47488 EAW69072 EAW69073 O43557 AF036581 AAC39563 AF064090 AAC25169 AK026704 AK292037 BAF84726 AY028261 AAK26160 AY358812 AAQ89171 BC018058 BC152848 AAI52849 CR541854 CAG46652 CR541871 CAG46669 XM_005259670 XP_005259727 XM_011528398 XP_011526700 XR_936212 NM_003807 NP_003798 NM_172014 NP_742011
Function	Cytokine that binds to TNFRSF3/LTBR. Binding to the decoy receptor TNFRSF6B modulates its effects. Activates NFKB, stimulates the proliferation of T-cells, and inhibits growth of the adenocarcinoma HT-29. Acts as a receptor for Herpes simplex virus.
Subcellular Location	Isoform 2: Cytoplasm.
Tissue Specificity	Predominantly expressed in the spleen but also found in the brain. Weakly expressed in peripheral lymphoid tissues and in heart, placenta, liver, lung, appendix, and kidney, and no expression seen in fetal tissues, endocrine glands, or nonhematopoietic tumor lines.
Top Pathways	Cytokine-cytokine receptor interaction, Herpes simplex infection

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human LIGHT gene - orb90972 from Biorbyt Prices $255.00 Sizes 10 μg Species Human

Mouse LIGHT/TNFSF14 (NP_062291) VersaClone cDNA - RDC1164 from R&D Systems Prices $199.00 Sizes 10 µg Species Mouse

Human LIGHT/TNFSF14 (NP_003798) VersaClone cDNA - RDC1242 from R&D Systems Prices $199.00 Sizes 10 µg Species Human

TNFSF14 - MBS1274172 from MyBioSource Prices $175.00 Sizes 10ug plasmid + 200ul glycerol stock Species Human Accession BC018058

Human TNFSF14 ORF Clone(NM_172014.2) - CDCR321317 from Creative Biomart Species Human Accession NM_172014.2

Human TNFSF14 ORF Clone(NM_172014.2) - CDCR321318 from Creative Biomart Species Human Accession NM_172014.2

Human TNFSF14 ORF Clone(NM_003807.3) - CDCL179251 from Creative Biomart Species Human Accession NM_003807.3

Human TNFSF14 ORF Clone(NM_003807.3) - CDCL179252 from Creative Biomart Species Human Accession NM_003807.3

human TNFSF14 ORF clone - CDCH093612 from Creative Biomart Species Human Accession NM_003807

human TNFSF14 ORF clone - CDCH093613 from Creative Biomart Species Human Accession NM_003807

human TNFSF14 ORF clone - CDCH093614 from Creative Biomart Species Human Accession NM_003807

human TNFSF14 ORF clone - CDCH093615 from Creative Biomart Species Human Accession NM_003807

human TNFSF14 ORF clone - CDCH093616 from Creative Biomart Species Human Accession NM_003807

human TNFSF14 ORF clone - CDCH093617 from Creative Biomart Species Human Accession NM_003807

Human TNFSF14/LIGHT/CD258 transcript variant 1 Gene ORF cDNA clone in cloning vector - HG10386-M from Sino Biological Species Human

Human TNFSF14/LIGHT/CD258 transcript variant 1 Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - HG10386-ACG from Sino Biological Species Human

Human TNFSF14/LIGHT/CD258 transcript variant 1 Gene ORF cDNA clone expression plasmid, N-His tag - HG10386-NH from Sino Biological Species Human

Human TNFSF14/LIGHT/CD258 transcript variant 1 Gene ORF cDNA clone expression plasmid, C-His tag - HG10386-CH from Sino Biological Species Human

Human TNFSF14/LIGHT/CD258 transcript variant 1 Gene ORF cDNA clone expression plasmid - HG10386-UT from Sino Biological Species Human

Human TNFSF14/LIGHT/CD258 transcript variant 1 Gene ORF cDNA clone expression plasmid, N-Flag tag - HG10386-NF from Sino Biological Species Human

Human TNFSF14/LIGHT/CD258 transcript variant 1 Gene ORF cDNA clone expression plasmid, N-Myc tag - HG10386-NM from Sino Biological Species Human

Human TNFSF14/LIGHT/CD258 transcript variant 1 Gene ORF cDNA clone expression plasmid, C-HA tag - HG10386-CY from Sino Biological Species Human

Human TNFSF14/LIGHT/CD258 transcript variant 1 Gene ORF cDNA clone expression plasmid, C-Flag tag - HG10386-CF from Sino Biological Species Human

Human TNFSF14/LIGHT/CD258 transcript variant 1 Gene ORF cDNA clone expression plasmid, N-HA tag - HG10386-NY from Sino Biological Species Human

Human TNFSF14/LIGHT/CD258 transcript variant 1 Gene ORF cDNA clone expression plasmid, C-Myc tag - HG10386-CM from Sino Biological Species Human

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