TNFSF14

Gene Symbol	TNFSF14
Entrez Gene	8740
Alt Symbol	CD258, HVEML, LIGHT, LTg, TR2
Species	Human
Gene Type	protein-coding
Description	tumor necrosis factor (ligand) superfamily, member 14
Other Description	delta transmembrane LIGHT|herpes virus entry mediator ligand|herpesvirus entry mediator A|herpesvirus entry mediator ligand|herpesvirus entry mediator-ligand|ligand for herpesvirus entry mediator|tumor necrosis factor ligand superfamily member 14|tumor necrosis factor receptor-like 2|tumor necrosis factor superfamily member LIGHT
Swissprots	A8K7M2 O43557 Q6FHA1 O75476 Q96LD2 C9J5H4 Q8WVF8
Accessions	AAN34658 CAL00173 CBX47488 EAW69072 EAW69073 O43557 AF036581 AAC39563 AF064090 AAC25169 AK026704 AK292037 BAF84726 AY028261 AAK26160 AY358812 AAQ89171 BC018058 BC152848 AAI52849 CR541854 CAG46652 CR541871 CAG46669 XM_005259670 XP_005259727 XM_011528398 XP_011526700 XR_936212 NM_003807 NP_003798 NM_172014 NP_742011
Function	Cytokine that binds to TNFRSF3/LTBR. Binding to the decoy receptor TNFRSF6B modulates its effects. Activates NFKB, stimulates the proliferation of T-cells, and inhibits growth of the adenocarcinoma HT-29. Acts as a receptor for Herpes simplex virus.
Subcellular Location	Isoform 2: Cytoplasm.
Tissue Specificity	Predominantly expressed in the spleen but also found in the brain. Weakly expressed in peripheral lymphoid tissues and in heart, placenta, liver, lung, appendix, and kidney, and no expression seen in fetal tissues, endocrine glands, or nonhematopoietic tumor lines.
Top Pathways	Cytokine-cytokine receptor interaction, Herpes simplex infection

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human LIGHT full length protein - ab132190 from Abcam Category Protein Source Wheat germ Species Human

Human LIGHT protein fragment - ab132189 from Abcam Category Protein Source Wheat germ Species Human

Human LIGHT protein fragment - ab82123 from Abcam Category Protein Source Insect cells Species Human

Human LIGHT protein fragment - ab109159 from Abcam Category Protein Source CHO Species Human

Mouse LIGHT protein fragment - ab50095 from Abcam Category Protein Source E. coli Species Mouse

TNFSF14 / LIGHT Antibody Blocking Peptide - LS-E3417 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

TNFSF14 / LIGHT Antibody Blocking Peptide - LS-E10661 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

TNFSF14 / LIGHT Antibody Blocking Peptide - LS-E27153 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

LIGHT/TNFSF14 Recombinant Protein - H00008740-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

LIGHT/TNFSF14 Partial Recombinant Protein - H00008740-Q01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Recombinant Human LIGHT/TNFSF14 Protein - H00008740-P02 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

LIGHT/TNFSF14 Recombinant Protein - H00008740-G01 from Novus Biologicals Category Protein Prices $579.00 Sizes 10 µg Species Human

TNFSF14-Antibody-Center-Blocking-Peptide - BP14595c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

LIGHT Recombinant Protein - GTX48109-PRO from GeneTex Category Protein Prices $299.00 Sizes 15 μg Species Human

TNFRSF14 blocking peptide - GTX89465-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human

LIGHT blocking peptide - GTX88321-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human

TAS1R2/GPR71 blocking peptide - GTX88873-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human

Recombinant Human LIGHT/TNFSF14 - 664-LI-025 from R&D Systems Category Protein Source Mouse myeloma cell line, NS0-derived

Recombinant Human LIGHT/TNFSF14, CF - 664-LI-025/CF from R&D Systems Category Protein Source Mouse myeloma cell line, NS0-derived

Recombinant human Tumor necrosis factor ligand superfamily member 14 protein (OPCA00671) - OPCA00671 from Aviva Systems Biology Category Protein Prices $220.00 Sizes 50 µg Species Human

Human TNFSF14 (His Tag) protein - orb232231 from Biorbyt Category Protein Prices $196.00, $323.00, $646.00 Sizes 5 μg, 20 μg, 100 μg Species Human

Murine LIGHT protein - orb223864 from Biorbyt Category Protein Prices $221.00, $357.00, $553.00, $910.00 Sizes 5 μg, 20 μg, 100 μg, 250 μg

Human HVEML protein - orb245307 from Biorbyt Category Protein Prices $340.00, $629.00, $1,003.00, $1,556.00 Sizes 50 μg, 200 μg, 500 μg, 1 mg Species Human

TNFSF14 Immunizing peptide - orb59691 from Biorbyt Category Peptide Prices $247.00 Sizes 100 μg Species Human, Mouse, Rat

LIGHT protein - 30R-AL019 from Fitzgerald Category Protein Prices $225.00 Sizes 20 µg Source E.coli

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