TNFSF14

Gene Symbol TNFSF14
Entrez Gene 8740
Alt Symbol CD258, HVEML, LIGHT, LTg, TR2
Species Human
Gene Type protein-coding
Description tumor necrosis factor (ligand) superfamily, member 14
Other Description delta transmembrane LIGHT|herpes virus entry mediator ligand|herpesvirus entry mediator A|herpesvirus entry mediator ligand|herpesvirus entry mediator-ligand|ligand for herpesvirus entry mediator|tumor necrosis factor ligand superfamily member 14|tumor necrosis factor receptor-like 2|tumor necrosis factor superfamily member LIGHT
Swissprots A8K7M2 O43557 Q6FHA1 O75476 Q96LD2 C9J5H4 Q8WVF8
Accessions AAN34658 CAL00173 CBX47488 EAW69072 EAW69073 O43557 AF036581 AAC39563 AF064090 AAC25169 AK026704 AK292037 BAF84726 AY028261 AAK26160 AY358812 AAQ89171 BC018058 BC152848 AAI52849 CR541854 CAG46652 CR541871 CAG46669 XM_005259670 XP_005259727 XM_011528398 XP_011526700 XR_936212 NM_003807 NP_003798 NM_172014 NP_742011
Function Cytokine that binds to TNFRSF3/LTBR. Binding to the decoy receptor TNFRSF6B modulates its effects. Activates NFKB, stimulates the proliferation of T-cells, and inhibits growth of the adenocarcinoma HT-29. Acts as a receptor for Herpes simplex virus.
Subcellular Location Isoform 2: Cytoplasm.
Tissue Specificity Predominantly expressed in the spleen but also found in the brain. Weakly expressed in peripheral lymphoid tissues and in heart, placenta, liver, lung, appendix, and kidney, and no expression seen in fetal tissues, endocrine glands, or nonhematopoietic tumor lines.
Top Pathways Cytokine-cytokine receptor interaction, Herpes simplex infection

LIGHT CRISPR/Cas9 KO Plasmid (h) - sc-403128 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

LIGHT HDR Plasmid (h) - sc-403128-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

LIGHT Double Nickase Plasmid (h) - sc-403128-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

LIGHT Double Nickase Plasmid (h2) - sc-403128-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

LIGHT CRISPR Activation Plasmid (h) - sc-403128-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

LIGHT CRISPR Activation Plasmid (h2) - sc-403128-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

LIGHT Lentiviral Activation Particles (h) - sc-403128-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

LIGHT Lentiviral Activation Particles (h2) - sc-403128-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

LIGHT siRNA (h) - sc-39674 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

LIGHT shRNA Plasmid (h) - sc-39674-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

LIGHT shRNA (h) Lentiviral Particles - sc-39674-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

LIGHT/TNFSF14 RNAi - H00008740-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

LIGHT/TNFSF14 RNAi - H00008740-R02 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU137531 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN21765 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND21765 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR02984 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr02984

TNFSF14 siRNA (Human) - CRH5758 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

TNFSF14 - MBS826882 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human TNFSF14 (NM_003807.3) - SHH432148 from Creative biogene

Category siRNA
Species Reactivities Human

Human TNFSF14 siRNA - orb266260 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

TNFSF14 shRNA Plasmid (Human) - CHH5758 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

TNFSF14 miRNA 3'UTR clone - MiUTR3H-06883 from Creative biogene

Species Reactivities Human

TNFSF14 miRNA 3'UTR clone - MiUTR3H-06884 from Creative biogene

Species Reactivities Human
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