PSMD14

Gene Symbol	PSMD14
Entrez Gene	10213
Alt Symbol	PAD1, POH1, RPN11
Species	Human
Gene Type	protein-coding
Description	proteasome (prosome, macropain) 26S subunit, non-ATPase, 14
Other Description	26S proteasome non-ATPase regulatory subunit 14|26S proteasome regulatory subunit rpn11|26S proteasome-associated PAD1 homolog 1
Swissprots	O00176 O00487 B3KNW2
Accessions	AAX88940 AAY15016 EAX11370 O00487 AB209220 BAD92457 AK055128 BAG51474 AK091095 BC009524 AAH09524 BC066336 AAH66336 BM978668 DA133201 U86782 AAC51866 NM_005805 NP_005796
Function	Metalloprotease component of the 26S proteasome that specifically cleaves 'Lys-63'-linked polyubiquitin chains. The 26S proteasome is involved in the ATP-dependent degradation of ubiquitinated proteins. Plays a role in response to double-strand breaks (DSBs): acts as a regulator of non-homologous end joining (NHEJ) by cleaving 'Lys-63'-linked polyubiquitin, thereby promoting retention of JMJD2A/KDM4A on chromatin and restricting TP53BP1 accumulation. Also involved in homologous recombination repair by promoting RAD51 loading. {ECO:0000269|PubMed:22909820, ECO:0000269|PubMed:9374539}.
Tissue Specificity	Widely expressed. Highest levels in heart and skeletal muscle. {ECO:0000269|PubMed:9374539}.
Top Pathways	Proteasome, Epstein-Barr virus infection

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human PSMD14 Gene cDNA Clone - orb144910 from Biorbyt Prices $264.00 Sizes 10 μg Species Human

PSMD14 - MBS1272335 from MyBioSource Prices $175.00 Sizes 10ug plasmid + 200ul glycerol stock Species Human Accession BC009524

PSMD14 - MBS1276133 from MyBioSource Prices $175.00 Sizes 10ug plasmid + 200ul glycerol stock Species Human Accession BC066336

Human PSMD14 ORF Clone(NM_005805.5) - CDCL172869 from Creative Biomart Species Human Accession NM_005805.5

Human PSMD14 ORF Clone(NM_005805.5) - CDCL172870 from Creative Biomart Species Human Accession NM_005805.5

Human PSMD14 Gene cDNA clone plasmid - HG15391-G from Sino Biological Species Human

Human PSMD14 Gene ORF cDNA clone expression plasmid, C-Flag tag - HG15391-CF from Sino Biological Species Human

Human PSMD14 Gene ORF cDNA clone expression plasmid, N-His tag - HG15391-NH from Sino Biological Species Human

Human PSMD14 Gene ORF cDNA clone expression plasmid, N-Myc tag - HG15391-NM from Sino Biological Species Human

Human PSMD14 Gene ORF cDNA clone expression plasmid, C-Myc tag - HG15391-CM from Sino Biological Species Human

Human PSMD14 Gene ORF cDNA clone expression plasmid, C-His tag - HG15391-CH from Sino Biological Species Human

Human PSMD14 Gene ORF cDNA clone expression plasmid - HG15391-UT from Sino Biological Species Human

Human PSMD14 Gene ORF cDNA clone expression plasmid, C-HA tag - HG15391-CY from Sino Biological Species Human

Human PSMD14 Gene ORF cDNA clone expression plasmid, N-GFPSpark tag - HG15391-ANG from Sino Biological Species Human

Human PSMD14 Gene ORF cDNA clone expression plasmid, C-OFPSpark tag - HG15391-ACR from Sino Biological Species Human

Human PSMD14 Gene ORF cDNA clone expression plasmid, N-OFPSpark tag - HG15391-ANR from Sino Biological Species Human

Human PSMD14 Gene ORF cDNA clone expression plasmid, N-Flag tag - HG15391-NF from Sino Biological Species Human

Human PSMD14 Gene ORF cDNA clone expression plasmid, N-HA tag - HG15391-NY from Sino Biological Species Human

Human PSMD14 Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - HG15391-ACG from Sino Biological Species Human

Human PSMD14 ORF Clone (BC009524) - CDCS412430 from Creative biogene Species Human Accession O00487

Human PSMD14 ORF Clone (BC066336) - CDCS412431 from Creative biogene Species Human Accession O00487

Human PSMD14 ORF clone (BC066336) - CDCB158206 from Creative biogene Species Human

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