PSMD14

Gene Symbol PSMD14
Entrez Gene 10213
Alt Symbol PAD1, POH1, RPN11
Species Human
Gene Type protein-coding
Description proteasome (prosome, macropain) 26S subunit, non-ATPase, 14
Other Description 26S proteasome non-ATPase regulatory subunit 14|26S proteasome regulatory subunit rpn11|26S proteasome-associated PAD1 homolog 1
Swissprots O00176 O00487 B3KNW2
Accessions AAX88940 AAY15016 EAX11370 O00487 AB209220 BAD92457 AK055128 BAG51474 AK091095 BC009524 AAH09524 BC066336 AAH66336 BM978668 DA133201 U86782 AAC51866 NM_005805 NP_005796
Function Metalloprotease component of the 26S proteasome that specifically cleaves 'Lys-63'-linked polyubiquitin chains. The 26S proteasome is involved in the ATP-dependent degradation of ubiquitinated proteins. Plays a role in response to double-strand breaks (DSBs): acts as a regulator of non-homologous end joining (NHEJ) by cleaving 'Lys-63'-linked polyubiquitin, thereby promoting retention of JMJD2A/KDM4A on chromatin and restricting TP53BP1 accumulation. Also involved in homologous recombination repair by promoting RAD51 loading. {ECO:0000269|PubMed:22909820, ECO:0000269|PubMed:9374539}.
Tissue Specificity Widely expressed. Highest levels in heart and skeletal muscle. {ECO:0000269|PubMed:9374539}.
Top Pathways Proteasome, Epstein-Barr virus infection

POH1 CRISPR/Cas9 KO Plasmid (h) - sc-405591 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

POH1 HDR Plasmid (h) - sc-405591-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

POH1 Double Nickase Plasmid (h) - sc-405591-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

POH1 Double Nickase Plasmid (h2) - sc-405591-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

POH1 CRISPR Activation Plasmid (h) - sc-405591-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

POH1 CRISPR Activation Plasmid (h2) - sc-405591-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

POH1 Lentiviral Activation Particles (h) - sc-405591-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

POH1 Lentiviral Activation Particles (h2) - sc-405591-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

POH1 siRNA (h) - sc-106427 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

POH1 shRNA Plasmid (h) - sc-106427-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

POH1 shRNA (h) Lentiviral Particles - sc-106427-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

PSMD14 RNAi - H00010213-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU030281 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN17619 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND17619 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

PSMD14 siRNA (Human) - CRH6902 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human PSMD14 (NM_005805.5) - SHH385408 from Creative biogene

Category siRNA
Species Reactivities Human

Human PSMD14 siRNA - orb267404 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

PSMD14 shRNA Plasmid (Human) - CHH6902 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

PSMD14 miRNA 3'UTR clone - MiUTR3H-09025 from Creative biogene

Species Reactivities Human
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