PSMD14

Gene Symbol	PSMD14
Entrez Gene	10213
Alt Symbol	PAD1, POH1, RPN11
Species	Human
Gene Type	protein-coding
Description	proteasome (prosome, macropain) 26S subunit, non-ATPase, 14
Other Description	26S proteasome non-ATPase regulatory subunit 14|26S proteasome regulatory subunit rpn11|26S proteasome-associated PAD1 homolog 1
Swissprots	O00176 O00487 B3KNW2
Accessions	AAX88940 AAY15016 EAX11370 O00487 AB209220 BAD92457 AK055128 BAG51474 AK091095 BC009524 AAH09524 BC066336 AAH66336 BM978668 DA133201 U86782 AAC51866 NM_005805 NP_005796
Function	Metalloprotease component of the 26S proteasome that specifically cleaves 'Lys-63'-linked polyubiquitin chains. The 26S proteasome is involved in the ATP-dependent degradation of ubiquitinated proteins. Plays a role in response to double-strand breaks (DSBs): acts as a regulator of non-homologous end joining (NHEJ) by cleaving 'Lys-63'-linked polyubiquitin, thereby promoting retention of JMJD2A/KDM4A on chromatin and restricting TP53BP1 accumulation. Also involved in homologous recombination repair by promoting RAD51 loading. {ECO:0000269|PubMed:22909820, ECO:0000269|PubMed:9374539}.
Tissue Specificity	Widely expressed. Highest levels in heart and skeletal muscle. {ECO:0000269|PubMed:9374539}.
Top Pathways	Proteasome, Epstein-Barr virus infection

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human PSMD14 full length protein - ab160883 from Abcam Category Protein Source Wheat germ Species Human

PSMD14 Antibody Blocking Peptide - LS-E6494 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

PSMD14 Antibody Blocking Peptide - LS-E11370 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

PSMD14 Antibody Blocking Peptide - LS-E11371 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human PSMD14 Protein - H00010213-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

PSMD14-Antibody-C-term-Blocking-Peptide - BP19256b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

PSMD14 - H00010213-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

PSMD14 - H00010213-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

PSMD14 fusion protein - Ag2694 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

Recombinant Human PAD1, GST-tagged - PSMD14-6978H from Creative Biomart Category Protein Source Sf9 Cells Species Human

Recombinant Human PSMD14, GST-tagged - PSMD14-2030H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Human 26S proteasome non-ATPase regulatory subunit 14(PSMD14) - CSB-YP018904HU CSB-EP018904HU CSB-BP018904HU CSB-MP018904HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

26S proteasome non-ATPase regulatory subunit 14 (PSMD14), Recombinant Protein - MBS1031209 from MyBioSource Category Protein Prices $1,070.00, $1,070.00, $1,300.00, $1,300.00, $1,670.00, $1,670.00, $2,135.00, $2,135.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

26S proteasome regulatory subunit RPN11 (RPN11), Recombinant Protein - MBS1299219 from MyBioSource Category Protein Prices $1,050.00, $1,050.00, $1,280.00, $1,280.00, $1,635.00, $1,635.00, $2,100.00, $2,100.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell

26S proteasome regulatory subunit RPN11 (RPN11), Recombinant Protein - MBS1284519 from MyBioSource Category Protein Prices $1,065.00, $1,065.00, $1,295.00, $1,295.00, $1,660.00, $1,660.00, $2,125.00, $2,125.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Candida

26S proteasome regulatory subunit RPN11 (RPN11), Recombinant Protein - MBS1459397 from MyBioSource Category Protein Prices $1,070.00, $1,070.00, $1,300.00, $1,300.00, $1,675.00, $1,675.00, $2,140.00, $2,140.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Ashbya gossypii

PSMD14 - TP309829 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

PSMD14 Recombinant Protein Antigen - NBP1-80956PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

PSMD14 Peptide, Human - M34GP12607H from Creative Peptides Category Peptide Source Synthetic. Species Human

PSMD14 Recombinant Protein Antigen - NBP2-58771PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

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