TXNIP

Gene Symbol TXNIP
Entrez Gene 10628
Alt Symbol EST01027, HHCPA78, THIF, VDUP1
Species Human
Gene Type protein-coding
Description thioredoxin interacting protein
Other Description thioredoxin binding protein 2|thioredoxin-binding protein 2|thioredoxin-interacting protein|upregulated by 1,25-dihydroxyvitamin D-3|vitamin D3 up-regulated protein 1
Swissprots Q6PML0 Q16226 B4E3D3 Q9BXG9 Q9H3M7
Accessions AAK37514 BAB18859 CAI22351 CAI22352 CCA65310 CCD57098 CCQ43360 EAW71410 EAW71411 Q9H3M7 AA805348 AK226090 AK301148 BAG62739 AK301203 BAG62780 AK304670 BAG65445 AY594328 AAT01927 BC024305 BC093702 AAH93702 BC093704 AAH93704 BF446648 BX404012 BX537824 DB058019 HY177853 S73591 AAB31977 NM_006472 NP_006463
Function May act as an oxidative stress mediator by inhibiting thioredoxin activity or by limiting its bioavailability. Interacts with COPS5 and restores COPS5-induced suppression of CDKN1B stability, blocking the COPS5-mediated translocation of CDKN1B from the nucleus to the cytoplasm. Functions as a transcriptional repressor, possibly by acting as a bridge molecule between transcription factors and corepressor complexes, and over- expression will induce G0/G1 cell cycle arrest. Required for the maturation of natural killer cells. Acts as a suppressor of tumor cell growth. Inhibits the proteasomal degradation of DDIT4, and thereby contributes to the inhibition of the mammalian target of rapamycin complex 1 (mTORC1). {ECO:0000269|PubMed:12821938, ECO:0000269|PubMed:17603038, ECO:0000269|PubMed:18541147, ECO:0000269|PubMed:21460850}.
Subcellular Location Cytoplasm {ECO:0000250}.

Human TXNIP ELISA Kit (Sandwich ELISA) - LS-F12885 from LifeSpan Bioscience

Category ELISA Kit
Prices $600.00
Sizes 1 plate
Sensitivity 0.156
Range 0.156-10 ng/ml

Thioredoxin Binding Protein 2, TBP2, Human, ELISA Kit - E-EL-H1729 from ARP American Research Products

Category ELISA Kit
Prices $522.00
Sizes 96 t
Sensitivity 0.094
Range 0.156-10ng/mL

Thioredoxin Binding Protein 2 (TBP2), Human, ELISA Kit - SEB162Hu from ARP American Research Products

Category ELISA Kit
Prices $685.00
Sizes 96 t
Sensitivity 0.066ng/mL
Range 0.156-10ng/mL

Thioredoxin-interacting protein (TXNIP), Human, ELISA Kit - CSB-EL025383HU from ARP American Research Products

Category ELISA Kit
Prices $495.00, $695.00, $696.00, $699.00
Sizes 48 t, 96 t, 5 x 96t, 10 x 96t
Sensitivity 3.9 pg/ml
Range 15.6 pg/ml-1000 pg/ml

Thioredoxin-interacting protein, TXNIP, Human, ELISA Kit - E1162h from ARP American Research Products

Category ELISA Kit
Prices $596.00
Sizes 96 t
Range 0.156-10 ng/mL

Thioredoxin Binding Protein 2, TBP2, Mouse, ELISA Kit - E-EL-M1131 from ARP American Research Products

Category ELISA Kit
Prices $585.00
Sizes 96 t
Sensitivity 0.188
Range 0.313-20ng/mL

Thioredoxin Binding Protein 2, TBP2, Rabbit, ELISA Kit - E-EL-RB0844 from ARP American Research Products

Category ELISA Kit
Prices $585.00
Sizes 96 t

Thioredoxin Binding Protein 2, TBP2, Chicken, ELISA Kit - E-EL-Ch1279 from ARP American Research Products

Category ELISA Kit
Prices $522.00
Sizes 96 t

Thioredoxin Binding Protein 2, TBP2, Porcine, ELISA Kit - E-EL-P0682 from ARP American Research Products

Category ELISA Kit
Prices $585.00
Sizes 96 t

Thioredoxin Binding Protein 2, TBP2, Guinea Pig, ELISA Kit - E-EL-GP0649 from ARP American Research Products

Category ELISA Kit
Prices $522.00
Sizes 96 t

Thioredoxin Binding Protein 2, TBP2, Monkey, ELISA Kit - E-EL-MK1026 from ARP American Research Products

Category ELISA Kit
Prices $585.00
Sizes 96 t

Thioredoxin Binding Protein 2, ELISA Kit - MBS062344 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Thioredoxin Binding Protein 2, ELISA Kit - MBS021130 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Thioredoxin Binding Protein 2, ELISA Kit - MBS035218 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Thioredoxin Binding Protein 2, ELISA Kit - MBS007325 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Thioredoxin Binding Protein 2, ELISA Kit - MBS086187 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Thioredoxin Binding Protein 2, ELISA Kit - MBS015795 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Thioredoxin Binding Protein 2, ELISA Kit - MBS035770 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Thioredoxin Binding Protein 2, ELISA Kit - MBS011708 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Thioredoxin Binding Protein 2, ELISA Kit - MBS019154 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Thioredoxin Binding Protein 2, ELISA Kit - MBS041174 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Thioredoxin Binding Protein 2, ELISA Kit - MBS090599 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Thioredoxin Binding Protein 2, ELISA Kit - MBS023033 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Thioredoxin Binding Protein 2, ELISA Kit - MBS005638 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
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