TXNIP

Gene Symbol	TXNIP
Entrez Gene	10628
Alt Symbol	EST01027, HHCPA78, THIF, VDUP1
Species	Human
Gene Type	protein-coding
Description	thioredoxin interacting protein
Other Description	thioredoxin binding protein 2|thioredoxin-binding protein 2|thioredoxin-interacting protein|upregulated by 1,25-dihydroxyvitamin D-3|vitamin D3 up-regulated protein 1
Swissprots	Q6PML0 Q16226 B4E3D3 Q9BXG9 Q9H3M7
Accessions	AAK37514 BAB18859 CAI22351 CAI22352 CCA65310 CCD57098 CCQ43360 EAW71410 EAW71411 Q9H3M7 AA805348 AK226090 AK301148 BAG62739 AK301203 BAG62780 AK304670 BAG65445 AY594328 AAT01927 BC024305 BC093702 AAH93702 BC093704 AAH93704 BF446648 BX404012 BX537824 DB058019 HY177853 S73591 AAB31977 NM_006472 NP_006463
Function	May act as an oxidative stress mediator by inhibiting thioredoxin activity or by limiting its bioavailability. Interacts with COPS5 and restores COPS5-induced suppression of CDKN1B stability, blocking the COPS5-mediated translocation of CDKN1B from the nucleus to the cytoplasm. Functions as a transcriptional repressor, possibly by acting as a bridge molecule between transcription factors and corepressor complexes, and over- expression will induce G0/G1 cell cycle arrest. Required for the maturation of natural killer cells. Acts as a suppressor of tumor cell growth. Inhibits the proteasomal degradation of DDIT4, and thereby contributes to the inhibition of the mammalian target of rapamycin complex 1 (mTORC1). {ECO:0000269|PubMed:12821938, ECO:0000269|PubMed:17603038, ECO:0000269|PubMed:18541147, ECO:0000269|PubMed:21460850}.
Subcellular Location	Cytoplasm {ECO:0000250}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human TXNIP peptide - ab97419 from Abcam Category Peptide

TXNIP Antibody Blocking Peptide - LS-E18745 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

TXNIP Recombinant Protein - H00010628-P01 from Novus Biologicals Category Protein Species Human

TXNIP Blocking Peptide - 33R-2201 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

TXNIP Blocking Peptide - 33R-9486 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

TXNIP / VDUP1 - H00010628-P01 from Acris Antibodies Category Protein Prices $310.00 Sizes 2 µg Species Human

TXNIP / VDUP1 - H00010628-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

TXNIP Peptide - 7941P from ProSci Category Peptide Species Human

TXNIP fusion protein - ag13009 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

Recombinant Thioredoxin Binding Protein 2 (TBP2) - RPB162Hu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

Recombinant Thioredoxin Binding Protein 2 (TBP2) - RPB162Mu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Mouse

Recombinant Thioredoxin Binding Protein 2 (TBP2) - RPB162Mu02 from Uscn Life Science Inc. Category Protein Source E.coli Species Mouse

Recombinant Thioredoxin Binding Protein 2 (TBP2) - RPB162Hu01 from Cloud-clone Category Protein Source E.coli Species Human

Recombinant Human Thioredoxin-interacting protein(TXNIP) - CSB-YP880966HU CSB-EP880966HU CSB-BP880966HU CSB-MP880966HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

TXNIP / VDUP1 - TP310804 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

Thioredoxin-interacting protein (TXNIP), Recombinant Protein - MBS1448817 from MyBioSource Category Protein Prices $305.00, $580.00, $950.00, $950.00, $1,170.00, $1,170.00, $1,400.00, $1,400.00, $1,860.00, $1,860.00, $1,860.00, $2,760.00 Sizes 50 µg (E-Coli), 200 µg (E-Coli), 50 µg (Baculovirus), 500 µg (E-Coli), 50 µg (Mammalian-Cell), 500 µg (Yeast), 1 mg (E-Coli), 100 µg (Baculovirus), 100 µg (Mammalian-Cell), 1 mg (Yeast), 500 µg (Baculovirus), 1 mg (Baculovirus) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

TXNIP Recombinant Protein Antigen - NBP1-84784PEP from Novus Biologicals Category Protein Prices $209.00 Sizes 100 µl Species Human

TXNIP Recombinant Protein Antigen - NBP2-49095PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E. coli Species Human

TXNIP-Blocking-PeptideN-term - BP19855a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

TXNIP Peptide, Human - M34GP16902H from Creative Peptides Category Peptide Source Synthetic. Species Human

TXNIP fusion protein - Ag26579 from Proteintech Group Category Protein Source E. coli -derived, PGEX-4T Species Human

Human TXNIP protein - orb54710 from Biorbyt Category Protein Prices $859.00, $910.00, $1,190.00 Sizes 10 μg, 50 μg, 100 μg Species Human

TXNIP fusion protein - Ag26710 from Proteintech Group Category Protein Source E. coli -derived, PET28a Species Human

Recombinant Thioredoxin-interacting protein(TXNIP) - CSB-CF880966HU(F1) from Cusabio Category Protein Source in vitro E.coli expression system Species Human

Recombinant Thioredoxin-interacting protein(TXNIP) - CSB-CF880966HU from Cusabio Category Protein Source in vitro E.coli expression system Species Human

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