ADM

Gene Symbol ADM
Entrez Gene 133
Alt Symbol AM, PAMP
Species Human
Gene Type protein-coding
Description adrenomedullin
Other Description preproadrenomedullin|proadrenomedullin N-20 terminal peptide
Swissprots Q6FGW2 D3DQV3 P35318 B2R793
Accessions AAC60642 AAZ38717 BAA07756 CBX47636 EAW68571 EAW68572 P35318 AK312893 BAG35740 BC015961 AAH15961 BQ021632 BT006902 AAP35548 CR541995 CAG46792 D14874 BAA03589 HY105655 NM_001124 NP_001115
Function AM and PAMP are potent hypotensive and vasodilatator agents. Numerous actions have been reported most related to the physiologic control of fluid and electrolyte homeostasis. In the kidney, am is diuretic and natriuretic, and both am and pamp inhibit aldosterone secretion by direct adrenal actions. In pituitary gland, both peptides at physiologically relevant doses inhibit basal ACTH secretion. Both peptides appear to act in brain and pituitary gland to facilitate the loss of plasma volume, actions which complement their hypotensive effects in blood vessels.
Subcellular Location Secreted.
Tissue Specificity Highest levels found in pheochromocytoma and adrenal medulla. Also found in lung, ventricle and kidney tissues.

Human ADM cDNA clone(NM_001124.1) - CDFH000390 from Creative Biomart

Species Human
Accession NM_001124.1

Human ADM ORF clone(NM_001124.1) - CDCL182605 from Creative Biomart

Species Human
Accession NM_001124.1

Human ADM ORF Clone(NM_001124.1) - CDCR348410 from Creative Biomart

Species Human
Accession NM_001124.1

Human ADM ORF Clone(NM_001124.1) - CDCR348411 from Creative Biomart

Species Human
Accession NM_001124.1

Human ADM ORF Clone(NM_001124.1) - CDCR348412 from Creative Biomart

Species Human
Accession NM_001124.1

Human ADM ORF Clone(NM_001124.1) - CDCL153233 from Creative Biomart

Species Human
Accession NM_001124.1

ADM - CL01080H01 from Elabscience

Species Human
Accession NM_001124.1

Human ADM ORF clone(NM_001124.1) - CDCL182605 from Creative biogene

Species Human

Human ADM cDNA Clone(NM_001124.1) - CDFH000390 from Creative biogene

Species Human
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