ADM

Gene Symbol ADM
Entrez Gene 133
Alt Symbol AM, PAMP
Species Human
Gene Type protein-coding
Description adrenomedullin
Other Description preproadrenomedullin|proadrenomedullin N-20 terminal peptide
Swissprots Q6FGW2 D3DQV3 P35318 B2R793
Accessions AAC60642 AAZ38717 BAA07756 CBX47636 EAW68571 EAW68572 P35318 AK312893 BAG35740 BC015961 AAH15961 BQ021632 BT006902 AAP35548 CR541995 CAG46792 D14874 BAA03589 HY105655 NM_001124 NP_001115
Function AM and PAMP are potent hypotensive and vasodilatator agents. Numerous actions have been reported most related to the physiologic control of fluid and electrolyte homeostasis. In the kidney, am is diuretic and natriuretic, and both am and pamp inhibit aldosterone secretion by direct adrenal actions. In pituitary gland, both peptides at physiologically relevant doses inhibit basal ACTH secretion. Both peptides appear to act in brain and pituitary gland to facilitate the loss of plasma volume, actions which complement their hypotensive effects in blood vessels.
Subcellular Location Secreted.
Tissue Specificity Highest levels found in pheochromocytoma and adrenal medulla. Also found in lung, ventricle and kidney tissues.

ADM CRISPR/Cas9 KO Plasmid (h) - sc-402779 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

ADM HDR Plasmid (h) - sc-402779-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ADM Double Nickase Plasmid (h) - sc-402779-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ADM Double Nickase Plasmid (h2) - sc-402779-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ADM CRISPR Activation Plasmid (h) - sc-402779-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

ADM CRISPR Activation Plasmid (h2) - sc-402779-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

ADM Lentiviral Activation Particles (h) - sc-402779-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ADM Lentiviral Activation Particles (h2) - sc-402779-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ADM siRNA (h) - sc-39273 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

ADM shRNA Plasmid (h) - sc-39273-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

ADM shRNA (h) Lentiviral Particles - sc-39273-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU043091 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN2886 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND2886 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR06010 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr06010

ADM siRNA (Human) - CRH0092 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

ADM - MBS8214425 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human ADM (NM_001124.1) - SHH232502 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human ADM(NM_001124.1) - SHG042881 from Creative biogene

Category siRNA
Species Reactivities Human

ADM shRNA Plasmid (Human) - CHH0092 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

ADM miRNA 3'UTR clone - MiUTR1H-00200 from Creative biogene

Species Reactivities Human
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