Gene Symbol | ADM |
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Entrez Gene | 133 |
Alt Symbol | AM, PAMP |
Species | Human |
Gene Type | protein-coding |
Description | adrenomedullin |
Other Description | preproadrenomedullin|proadrenomedullin N-20 terminal peptide |
Swissprots | Q6FGW2 D3DQV3 P35318 B2R793 |
Accessions | AAC60642 AAZ38717 BAA07756 CBX47636 EAW68571 EAW68572 P35318 AK312893 BAG35740 BC015961 AAH15961 BQ021632 BT006902 AAP35548 CR541995 CAG46792 D14874 BAA03589 HY105655 NM_001124 NP_001115 |
Function | AM and PAMP are potent hypotensive and vasodilatator agents. Numerous actions have been reported most related to the physiologic control of fluid and electrolyte homeostasis. In the kidney, am is diuretic and natriuretic, and both am and pamp inhibit aldosterone secretion by direct adrenal actions. In pituitary gland, both peptides at physiologically relevant doses inhibit basal ACTH secretion. Both peptides appear to act in brain and pituitary gland to facilitate the loss of plasma volume, actions which complement their hypotensive effects in blood vessels. |
Subcellular Location | Secreted. |
Tissue Specificity | Highest levels found in pheochromocytoma and adrenal medulla. Also found in lung, ventricle and kidney tissues. |
Human Adrenomedullin peptide - ab69116 from Abcam
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Human Adrenomedullin protein fragment - ab114526 from Abcam
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ADM / Adrenomedullin Antibody Blocking Peptide - LS-E7689 from LifeSpan Bioscience
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ADM / Adrenomedullin Antibody Blocking Peptide - LS-E18626 from LifeSpan Bioscience
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Recombinant Human Adrenomedullin/ADM Protein - H00000133-Q01 from Novus Biologicals
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ADM-Antibody-Center-Blocking-Peptide - BP5006c from Abgent, a WuXi AppTec company
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Adrenomedullin-16-31-human-pig - SP2554b from Abgent, a WuXi AppTec company
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Adrenomedullin-16-31-human-pig - SP2554a from Abgent, a WuXi AppTec company
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Pro-Adrenomedullin-N-20-human - SP2522b from Abgent, a WuXi AppTec company
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Pro-Adrenomedullin-N-20-human - SP2522a from Abgent, a WuXi AppTec company
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Adrenomedullin-22-52-human - SP3206b from Abgent, a WuXi AppTec company
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Adrenomedullin-22-52-human - SP3206a from Abgent, a WuXi AppTec company
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Adrenomedullin-13-52-human - SP3106b from Abgent, a WuXi AppTec company
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Adrenomedullin-13-52-human - SP3106a from Abgent, a WuXi AppTec company
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Adrenomedullin-1-52-human - SP3415b from Abgent, a WuXi AppTec company
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Adrenomedullin-1-52-human - SP3415a from Abgent, a WuXi AppTec company
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Adrenomedullin-1-12-human - SP3413b from Abgent, a WuXi AppTec company
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Adrenomedullin-1-12-human - SP3413a from Abgent, a WuXi AppTec company
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Adrenomedullin Protein - GTX109260-pro from GeneTex
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Human ADM protein - orb138133 from Biorbyt
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Human ADM protein - orb244001 from Biorbyt
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Human ADM protein - orb245729 from Biorbyt
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Adrenomedullin (22-52) peptide - orb99709 from Biorbyt
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Adrenomedullin (1-52) peptide - orb99517 from Biorbyt
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Adrenomedullin (22-52) peptide - orb216432 from Biorbyt
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