GALNT15

Gene Symbol GALNT15
Entrez Gene 117248
Alt Symbol GALNACT15, GALNT13, GALNT7, GALNTL2, PIH5
Species Human
Gene Type protein-coding
Description polypeptide N-acetylgalactosaminyltransferase 15
Other Description UDP-GalNAc transferase T15|UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase-like protein 2|UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 15|UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 7|UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 2|galNAc-T-like protein 2|polypeptide GalNAc transferase 15|polypeptide GalNAc transferase-like protein 2|polypeptide N-acetylgalactosaminyltransferase 13|polypeptide N-acetylgalactosaminyltransferase-like protein 2|pp-GaNTase-like protein 2|pp-GalNAc-T15|pregnancy-induced hypertension syndrome-related protein 5|protein-UDP acetylgalactosaminyltransferase-like protein 2
Swissprots Q86T60 Q96C46 F1LIP6 B2R638 Q8N3T1 A6NMN1 Q96DJ5
Accessions CAG32963 CAK32357 EAW64266 EAW64267 Q8N3T1 AB078149 BAD29961 AF361251 AAK48940 AJ505964 CAD44542 AK094780 BAG52928 AK225673 AK312425 BAG35335 AL831925 CAD38585 AL832575 CAD89983 AL832736 AM392821 CAL37699 AM393321 CAL38199 AY035399 AAK63127 AY358443 AAQ88808 BC014789 AAH14789 BC030625 AAH30625 DQ891053 ABM81979 DQ894232 ABM85158 XM_005264851 XP_005264908 XM_005264852 XP_005264909 NM_054110 NP_473451
Function Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D- galactosamine residue to a serine or threonine residue on the protein receptor. Although it displays a much weaker activity toward all substrates tested compared to GALNT2, it is able to transfer up to seven GalNAc residues to the Muc5AC peptide, suggesting that it can fill vicinal Thr/Ser residues in cooperation with other GALNT proteins. Prefers Muc1a as substrate.
Subcellular Location Golgi apparatus membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}.
Tissue Specificity Widely expressed. Highly expressed in small intestine, placenta, spleen, cerebral cortex and ovary. Expressed at intermediate level in uterus, mammary gland, stomach, cerebellum and whole brain. Weakly expressed in fetal brain, bone marrow, thyroid gland, thymus, heart, skeletal muscle, lung, liver, colon, pancreas, kidney and testis. Not expressed in leukocyte. Expressed in both normal and osteoarthritic cartilage. Expressed at low level in chondrocytes in all zones of both normal and osteoarthritic cartilage. {ECO:0000269|PubMed:11597177, ECO:0000269|PubMed:15147861}.
Top Pathways Mucin type O-Glycan biosynthesis

Anti-GALNTL2 antibody [EPR11580] - ab174275 from Abcam

Prices $357.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR11580
All lanes : Anti-GALNTL2 antibody [EPR11580] (ab174275) at 1/1000 dilutionLane 1 : K562 lysatesLane 2 : Human placenta lysatesLane 3 : Caco 2 lysatesLane 4 : JAR lysatesLane 5 : MCF7 lysatesLane 6 : Human fetal brain lysatesLysates/proteins at 10 µg per lane.

Anti-GALNT15 / GALNTL2 Antibody (aa21-70) - LS-C187176 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot of Human PANC1. GALNT15 antibody dilution 1.0 ug/ml.

GALNTL2 Antibody - NBP1-81844 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry: GALNTL2 Antibody [NBP1-81844] - Staining of human stomach shows strong positivity in Parietal cells.

Anti-GALNTL2 antibody produced in rabbit - HPA017076 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-GALNTL2: <B>Cat. No. HPA017076</B>: Immunoperoxidase staining of formalin-fixed, paraffin-embedded human stomach shows strong positivity in Parietal cells.

GALNT15 Antibody - N-terminal region (ARP50238_P050) - ARP50238_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

GALNT13 antibody, N-term - GTX16278 from GeneTex

Prices $329.00
Sizes 50 μg
Host Rabbit
Clonality Polyclonal
Anti-GALNT13 antibody, N-term used in Western blot. GTX16278

GALNT13 antibody [N3C3] - GTX119021 from GeneTex

Host Rabbit
Clonality Polyclonal

GALNT7 antibody [C1C3] - GTX119421 from GeneTex

Prices $119.00
Sizes 25 μl
Host Rabbit
Clonality Polyclonal
Anti-GALNT7 antibody [C1C3] used in IHC (Formalin-fixed paraffin-embedded sections). GTX119421

GALNT7 antibody [N1C2] - GTX106068 from GeneTex

Prices $119.00
Sizes 25 μl
Host Rabbit
Clonality Polyclonal
Anti-GALNT7 antibody [N1C2] used in ICC/IF. GTX106068

GALNT7 antibody - orb74250 from Biorbyt

Prices $723.00
Sizes 100 μl
Host Rabbit
Clonality Polyclonal
Western Blot analysis of A:A431 whole cell lysate using GALNT7 antibody

GALNT7 antibody - orb77574 from Biorbyt

Prices $425.00
Sizes 100 μg
Host Rabbit
Clonality Polyclonal
Western blot analysis of fetal stomach lysate using GALNT7 antibody

GALNT7 antibody - 70R-17415 from Fitzgerald

Prices $375.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal

GALNTL2 antibody - 70R-17416 from Fitzgerald

Prices $375.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal

GALNT13 Antibody - abx030102 from Abbexa

Host Rabbit
Clonality Polyclonal

GALNT7 Antibody - abx038244 from Abbexa

Host Rabbit
Clonality Polyclonal

GALNTL2 antibody - 16900-1-AP from Acris Antibodies

Prices $270.00
Sizes 150 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemical of paraffin-embedded human placenta using 16900-1-AP(GALNTL2 antibody) at dilution of 1:50 (under 10x lens)

Anti-GALNT14, Polyclonal Antibody - 25-A4973 from ARP American Research Products

Prices $279.00, $549.00
Sizes 50 µg, 200 µg
Host Rabbit
Clonality Polyclonal
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