GALNT15

Gene Symbol	GALNT15
Entrez Gene	117248
Alt Symbol	GALNACT15, GALNT13, GALNT7, GALNTL2, PIH5
Species	Human
Gene Type	protein-coding
Description	polypeptide N-acetylgalactosaminyltransferase 15
Other Description	UDP-GalNAc transferase T15|UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase-like protein 2|UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 15|UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 7|UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 2|galNAc-T-like protein 2|polypeptide GalNAc transferase 15|polypeptide GalNAc transferase-like protein 2|polypeptide N-acetylgalactosaminyltransferase 13|polypeptide N-acetylgalactosaminyltransferase-like protein 2|pp-GaNTase-like protein 2|pp-GalNAc-T15|pregnancy-induced hypertension syndrome-related protein 5|protein-UDP acetylgalactosaminyltransferase-like protein 2
Swissprots	Q86T60 Q96C46 F1LIP6 B2R638 Q8N3T1 A6NMN1 Q96DJ5
Accessions	CAG32963 CAK32357 EAW64266 EAW64267 Q8N3T1 AB078149 BAD29961 AF361251 AAK48940 AJ505964 CAD44542 AK094780 BAG52928 AK225673 AK312425 BAG35335 AL831925 CAD38585 AL832575 CAD89983 AL832736 AM392821 CAL37699 AM393321 CAL38199 AY035399 AAK63127 AY358443 AAQ88808 BC014789 AAH14789 BC030625 AAH30625 DQ891053 ABM81979 DQ894232 ABM85158 XM_005264851 XP_005264908 XM_005264852 XP_005264909 NM_054110 NP_473451
Function	Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D- galactosamine residue to a serine or threonine residue on the protein receptor. Although it displays a much weaker activity toward all substrates tested compared to GALNT2, it is able to transfer up to seven GalNAc residues to the Muc5AC peptide, suggesting that it can fill vicinal Thr/Ser residues in cooperation with other GALNT proteins. Prefers Muc1a as substrate.
Subcellular Location	Golgi apparatus membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}.
Tissue Specificity	Widely expressed. Highly expressed in small intestine, placenta, spleen, cerebral cortex and ovary. Expressed at intermediate level in uterus, mammary gland, stomach, cerebellum and whole brain. Weakly expressed in fetal brain, bone marrow, thyroid gland, thymus, heart, skeletal muscle, lung, liver, colon, pancreas, kidney and testis. Not expressed in leukocyte. Expressed in both normal and osteoarthritic cartilage. Expressed at low level in chondrocytes in all zones of both normal and osteoarthritic cartilage. {ECO:0000269|PubMed:11597177, ECO:0000269|PubMed:15147861}.
Top Pathways	Mucin type O-Glycan biosynthesis

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human GALNT13 full length protein - ab165043 from Abcam Category Protein Source Wheat germ Species Human

Human GALNT13 protein fragment - ab165044 from Abcam Category Protein Source Wheat germ Species Human

Human GALNTL2 full length protein - ab165133 from Abcam Category Protein Source Wheat germ Species Human

GALNT13 Antibody Blocking Peptide - LS-E5678 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

GALNT13 Antibody Blocking Peptide - LS-E18140 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

GALNT15 / GALNTL2 Antibody Blocking Peptide - LS-E18149 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human GALNT13 Protein - H00114805-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human GALNT13 Protein - H00114805-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human Polypeptide GalNac Transferase 7/GALNT7 Protein - H00051809-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Polypeptide GalNac Transferase 7/GALNT7 Partial Recombinant Protein - H00051809-Q01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Recombinant Human GALNTL2 Protein - H00117248-P01 from Novus Biologicals Category Protein Prices $250.00 Sizes 2 µg Source Wheat Germ Species Human

GALNTL2-Antibody-N-term-Blocking-Peptide - BP9335a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Human GALNT7 (His Tag) protein - orb179768 from Biorbyt Category Protein Prices $298.00, $400.00 Sizes 10 μg, 20 μg Source Human Cells Species Human

GALNT13 Blocking Peptide - 33R-1754 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

GALNTL2 - H00117248-P01-10 from Acris Antibodies Category Protein Prices $370.00 Sizes 10 µg Species Human

GALNTL2 - H00117248-P01-25 from Acris Antibodies Category Protein Prices $520.00 Sizes 25 µg Species Human

GALNTL2 fusion protein - ag10434 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

GALNTL2 fusion protein - ag10455 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

Recombinant Human GALNTL2 - GALNTL2-1490H from Creative Biomart Category Protein Source Mammalian Cells Species Human

Human GALNT7 Protein (His Tag) - 15197-H08H-20 from Sino Biological Category Protein Prices $178.00, $178.00 Sizes 10 µg, 20 µg Source Human Cells Species Human

Recombinant Human Polypeptide N-acetylgalactosaminyltransferase-like protein 2(GALNTL2) - CSB-YP822698HU CSB-EP822698HU CSB-BP822698HU CSB-MP822698HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

GALNTL2 - TP303849 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

GALNT13 Recombinant Protein Antigen - NBP2-31837PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

Polypeptide GalNac Transferase 7/GALNT7 Protein - NBP2-39054PEP from Novus Biologicals Category Protein Prices $209.00 Sizes 100 µl Species Human

Polypeptide GalNac Transferase 7/GALNT7 Protein - NBP2-39021PEP from Novus Biologicals Category Protein Prices $209.00 Sizes 100 µl Species Human

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