GALNT15

Gene Symbol GALNT15
Entrez Gene 117248
Alt Symbol GALNACT15, GALNT13, GALNT7, GALNTL2, PIH5
Species Human
Gene Type protein-coding
Description polypeptide N-acetylgalactosaminyltransferase 15
Other Description UDP-GalNAc transferase T15|UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase-like protein 2|UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 15|UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 7|UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 2|galNAc-T-like protein 2|polypeptide GalNAc transferase 15|polypeptide GalNAc transferase-like protein 2|polypeptide N-acetylgalactosaminyltransferase 13|polypeptide N-acetylgalactosaminyltransferase-like protein 2|pp-GaNTase-like protein 2|pp-GalNAc-T15|pregnancy-induced hypertension syndrome-related protein 5|protein-UDP acetylgalactosaminyltransferase-like protein 2
Swissprots Q86T60 Q96C46 F1LIP6 B2R638 Q8N3T1 A6NMN1 Q96DJ5
Accessions CAG32963 CAK32357 EAW64266 EAW64267 Q8N3T1 AB078149 BAD29961 AF361251 AAK48940 AJ505964 CAD44542 AK094780 BAG52928 AK225673 AK312425 BAG35335 AL831925 CAD38585 AL832575 CAD89983 AL832736 AM392821 CAL37699 AM393321 CAL38199 AY035399 AAK63127 AY358443 AAQ88808 BC014789 AAH14789 BC030625 AAH30625 DQ891053 ABM81979 DQ894232 ABM85158 XM_005264851 XP_005264908 XM_005264852 XP_005264909 NM_054110 NP_473451
Function Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D- galactosamine residue to a serine or threonine residue on the protein receptor. Although it displays a much weaker activity toward all substrates tested compared to GALNT2, it is able to transfer up to seven GalNAc residues to the Muc5AC peptide, suggesting that it can fill vicinal Thr/Ser residues in cooperation with other GALNT proteins. Prefers Muc1a as substrate.
Subcellular Location Golgi apparatus membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}.
Tissue Specificity Widely expressed. Highly expressed in small intestine, placenta, spleen, cerebral cortex and ovary. Expressed at intermediate level in uterus, mammary gland, stomach, cerebellum and whole brain. Weakly expressed in fetal brain, bone marrow, thyroid gland, thymus, heart, skeletal muscle, lung, liver, colon, pancreas, kidney and testis. Not expressed in leukocyte. Expressed in both normal and osteoarthritic cartilage. Expressed at low level in chondrocytes in all zones of both normal and osteoarthritic cartilage. {ECO:0000269|PubMed:11597177, ECO:0000269|PubMed:15147861}.
Top Pathways Mucin type O-Glycan biosynthesis

Human-GALNTL2-cDNA-Clone - DC03935 from Abgent, a WuXi AppTec company

Prices $862.65
Sizes 10 µg
Species Human
Accession BC014789

GALNTL2 - MBS1272191 from MyBioSource

Prices $175.00
Sizes 10ug plasmid + 200ul glycerol stock
Species Human
Accession BC014789

Human GALNTL2 ORF Clone(NM_054110.4) - CDCL164315 from Creative Biomart

Species Human
Accession NM_054110.4

Mouse GALNTL2 ORF clone - CDCL110539 from Creative Biomart

Species Human
Accession NM_054110

Mouse GALNTL2 ORF clone - CDCL110540 from Creative Biomart

Species Human
Accession NM_054110

Human GALNT15 Gene cDNA clone plasmid - HG13692-G from Sino Biological

Species Human

Human GALNT15 natural ORF mammalian expression plasmid, C-GFPSpark tag - HG13692-ACG from Sino Biological

Species Human
Accession BC014789

Human GALNT15 natural ORF mammalian expression plasmid, C-OFPSpark tag - HG13692-ACR from Sino Biological

Species Human
Accession BC014789

Human GALNT15 natural ORF mammalian expression plasmid, N-Flag tag - HG13692-NF from Sino Biological

Species Human
Accession BC014789

Human GALNT15 natural ORF mammalian expression plasmid, C-Myc tag - HG13692-CM from Sino Biological

Species Human
Accession BC014789

Human GALNTL2 ORF Clone (BC014789) - CDCS416615 from Creative biogene

Species Human
Accession Q8N3T1

Human GALNT13 ORF clone (BC101032) - CDCB157684 from Creative biogene

Species Human

Human GALNT7 ORF clone (BC046129) - CDCB158335 from Creative biogene

Species Human

Human GALNT15 ORF clone (BC014789) - CDCB159768 from Creative biogene

Species Human

Human GALNTL2 Gene cDNA Clone - orb143316 from Biorbyt

Prices $264.00
Sizes 10 μg
Species Human

Human GALNT13 Gene cDNA Clone - orb143309 from Biorbyt

Prices $264.00
Sizes 10 μg
Species Human

Human GALNT7 Gene cDNA Clone - orb143314 from Biorbyt

Prices $264.00
Sizes 10 μg
Species Human
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