FRS2

Gene Symbol	FRS2
Entrez Gene	10818
Alt Symbol	FRS2A, FRS2alpha, SNT, SNT-1, SNT1
Species	Human
Gene Type	protein-coding
Description	fibroblast growth factor receptor substrate 2
Other Description	FGFR signalling adaptor|FGFR substrate 2|FGFR-signaling adaptor SNT|suc1-associated neurotrophic factor target 1
Swissprots	Q7LDQ6 O43558 B0LPF2 B2R684 Q8WU20
Accessions	ABY87531 AGC09590 EAW97225 EAW97226 EAW97227 Q8WU20 AF036717 AAB92554 AK226068 AK312477 BAG35381 BC021562 AAH21562 BP217337 BP230333 BP280775 BP311537 BP363404 BU166503 BX647520 BX647544 CD677411 DA189114 DA311708 DA721439 DA762876 DB081843 DR003634 JF432165 ADZ15382 NM_001042555 NP_001036020 NM_001278351 NP_001265280 NM_001278353 NP_001265282 NM_001278354 NP_001265283 NM_001278355 NP_001265284 NM_001278356 NP_001265285 NM_001278357 NP_001265286 NM_006654 NP_006645
Function	Adapter protein that links activated FGR and NGF receptors to downstream signaling pathways. Plays an important role in the activation of MAP kinases and in the phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3- kinase, in response to ligand-mediated activation of FGFR1. Modulates signaling via SHC1 by competing for a common binding site on NTRK1. {ECO:0000269|PubMed:12974390, ECO:0000269|PubMed:21765395}.
Subcellular Location	Endomembrane system. Note=Cytoplasmic, membrane-bound.
Tissue Specificity	Highly expressed in heart, brain, spleen, lung, liver, skeletal muscle, kidney and testis. {ECO:0000269|PubMed:10092678}.
Top Pathways	Neurotrophin signaling pathway, Proteoglycans in cancer

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Mouse/Human Phospho-FRS2 (Tyr436) ELISA Kit (Cell-Based Phosphorylation ELISA) - LS-F1715 from LifeSpan Bioscience Category ELISA Kit Prices $550.00 Sizes 1 plate Range 7.813-500 pg/ml

Mouse/Human FRS2 ELISA Kit (Cell-Based ELISA) - LS-F2002 from LifeSpan Bioscience Category ELISA Kit Prices $450.00 Sizes 1 plate Range 7.813-500 pg/ml

Human/Mouse/Rat Phospho-FRS2 (Y436) Cell-Based ELISA - KCB5126 from R&D Systems Category ELISA Kit Prices $459.00 Sizes 1 kit

Human FRS2 DuoSet ELISA - DY4069-05 from R&D Systems Category ELISA Kit Prices $299.00 Sizes 1 kit (for 5 Plates) Range 31.20 - 2,000 pg/mL

Fibroblast Growth Factor Receptor SubstRate 2, Human, ELISA Kit - E01F0125 from ARP American Research Products Category ELISA Kit Prices $535.00, $735.00 Sizes 48 t, 96 t Sensitivity 1.0pg/ml Range 25-500pg/ml

Fibroblast Growth Factor Receptor Substrate 2, FRS2, Human, ELISA Kit - E-EL-H1120 from ARP American Research Products Category ELISA Kit Prices $522.00 Sizes 96 t Sensitivity 9.375 Range 15.625-1000pg/mL

Fibroblast Growth Factor Receptor Substrate 2, FRS2, Mouse, ELISA Kit - E-EL-M0502 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t Sensitivity 4.688 Range 7.813-500pg/mL

Fibroblast Growth Factor Receptor Substrate 2, FRS2, Rabbit, ELISA Kit - E-EL-RB1243 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

Fibroblast Growth Factor Receptor Substrate 2, FRS2, Chicken, ELISA Kit - E-EL-Ch0915 from ARP American Research Products Category ELISA Kit Prices $504.00 Sizes 96 t

Fibroblast Growth Factor Receptor Substrate 2, FRS2, Porcine, ELISA Kit - E-EL-P0494 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

Fibroblast Growth Factor Receptor Substrate 2, FRS2, Sheep, ELISA Kit - E-EL-S0274 from ARP American Research Products Category ELISA Kit Prices $648.00 Sizes 96 t

Fibroblast Growth Factor Receptor Substrate 2, FRS2, Guinea Pig, ELISA Kit - E-EL-GP0318 from ARP American Research Products Category ELISA Kit Prices $522.00 Sizes 96 t

Fibroblast Growth Factor Receptor Substrate 2, FRS2, Monkey, ELISA Kit - E-EL-MK0841 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

FRS2 (Human) IP-WB Antibody Pair - H00010818-PW1 from Acris Antibodies Category Antibody Pair Prices $610.00 Sizes 1 set

Human FRS2 ELISA Kit - HF0132 from NeoScientific Category ELISA Kit Prices $495.00 Sizes 96 t

Anserine FRS2 ELISA Kit - AF0132 from NeoScientific Category ELISA Kit Prices $495.00 Sizes 96 t

Fibroblast Growth Factor Receptor Substrate 2, ELISA Kit - MBS015105 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Fibroblast Growth Factor Receptor Substrate 2, ELISA Kit - MBS036102 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.1ng/ml. Range 0.5ng/ml-16ng/ml.

Fibroblast Growth Factor Receptor SubstRate 2, ELISA Kit - MBS731149 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 1.0 pg/mL.

Fibroblast Growth Factor Receptor Substrate 2, ELISA Kit - MBS015889 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Fibroblast Growth Factor Receptor Substrate 2, ELISA Kit - MBS017683 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Fibroblast Growth Factor Receptor Substrate 2, ELISA Kit - MBS029974 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Fibroblast Growth Factor Receptor Substrate 2, ELISA Kit - MBS072474 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Fibroblast Growth Factor Receptor Substrate 2, ELISA Kit - MBS016927 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Fibroblast Growth Factor Receptor Substrate 2, ELISA Kit - MBS720415 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Search more