FRS2

Gene Symbol FRS2
Entrez Gene 10818
Alt Symbol FRS2A, FRS2alpha, SNT, SNT-1, SNT1
Species Human
Gene Type protein-coding
Description fibroblast growth factor receptor substrate 2
Other Description FGFR signalling adaptor|FGFR substrate 2|FGFR-signaling adaptor SNT|suc1-associated neurotrophic factor target 1
Swissprots Q7LDQ6 O43558 B0LPF2 B2R684 Q8WU20
Accessions ABY87531 AGC09590 EAW97225 EAW97226 EAW97227 Q8WU20 AF036717 AAB92554 AK226068 AK312477 BAG35381 BC021562 AAH21562 BP217337 BP230333 BP280775 BP311537 BP363404 BU166503 BX647520 BX647544 CD677411 DA189114 DA311708 DA721439 DA762876 DB081843 DR003634 JF432165 ADZ15382 NM_001042555 NP_001036020 NM_001278351 NP_001265280 NM_001278353 NP_001265282 NM_001278354 NP_001265283 NM_001278355 NP_001265284 NM_001278356 NP_001265285 NM_001278357 NP_001265286 NM_006654 NP_006645
Function Adapter protein that links activated FGR and NGF receptors to downstream signaling pathways. Plays an important role in the activation of MAP kinases and in the phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3- kinase, in response to ligand-mediated activation of FGFR1. Modulates signaling via SHC1 by competing for a common binding site on NTRK1. {ECO:0000269|PubMed:12974390, ECO:0000269|PubMed:21765395}.
Subcellular Location Endomembrane system. Note=Cytoplasmic, membrane-bound.
Tissue Specificity Highly expressed in heart, brain, spleen, lung, liver, skeletal muscle, kidney and testis. {ECO:0000269|PubMed:10092678}.
Top Pathways Neurotrophin signaling pathway, Proteoglycans in cancer

Human-FRS2-cDNA-Clone - DC05105 from Abgent, a WuXi AppTec company

Prices $691.20
Sizes 10 µg
Species Human
Accession BC021562

FRS2 - MBS1278477 from MyBioSource

Prices $175.00
Sizes 10ug plasmid + 200ul glycerol stock
Species Human
Accession BC021562

Human FRS2 cDNA clone(NM_001042555.1) - CDFH007128 from Creative Biomart

Species Human
Accession NM_001042555.1

Human FRS2 ORF clone - CDCL109563 from Creative Biomart

Species Human
Accession NM_001042555

Human FRS2 ORF clone - CDCL109564 from Creative Biomart

Species Human
Accession NM_001042555

Human FRS2 ORF clone - CDCL109565 from Creative Biomart

Species Human
Accession NM_001042555

Human FRS2 ORF clone - CDCL109566 from Creative Biomart

Species Human
Accession NM_001042555

Human FRS2 ORF Clone(NM_006654.3) - CDCL164012 from Creative Biomart

Species Human
Accession NM_006654.3

Human FRS2 ORF Clone(NM_001042555.1) - CDCL164013 from Creative Biomart

Species Human
Accession NM_001042555.1

Human FRS2 ORF Clone(NM_006654.3) - CDCR293231 from Creative Biomart

Species Human
Accession NM_006654.3

Human FRS2 ORF Clone(NM_006654.3) - CDCR293232 from Creative Biomart

Species Human
Accession NM_006654.3

Human FRS2 ORF Clone(NM_006654.3) - CDCR293233 from Creative Biomart

Species Human
Accession NM_006654.3

Human FRS2 ORF Clone(NM_001042555.1) - CDCR344613 from Creative Biomart

Species Human
Accession NM_001042555.1

Human FRS2 ORF Clone(NM_001042555.1) - CDCR344614 from Creative Biomart

Species Human
Accession NM_001042555.1

Human FRS2 ORF Clone(NM_006654.3) - CDCR293231 from Creative biogene

Species Human

Human FRS2 ORF Clone(NM_001042555.1) - CDCR344613 from Creative biogene

Species Human

Human FRS2 ORF Clone (BC021562) - CDCS407122 from Creative biogene

Species Human
Accession Q8WU20

Human FRS2 cDNA Clone(NM_001042555.1) - CDFH007128 from Creative biogene

Species Human
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