MED28

Gene Symbol MED28
Entrez Gene 80306
Alt Symbol 1500003D12Rik, EG1, magicin
Species Human
Gene Type protein-coding
Description mediator complex subunit 28
Other Description endothelial-derived gene 1|endothelial-derived protein 1|mediator of RNA polymerase II transcription subunit 28|mediator of RNA polymerase II transcription, subunit 28 homolog|merlin and Grb2-interacting cytoskeletal protein|tumor angiogenesis marker EG-1
Swissprots Q9H204 Q9BZJ5
Accessions EAW92781 EAW92782 Q9H204 AF317678 AF317679 AF317680 AAK11563 AF318059 AAL26906 AF358829 AAK32724 AK313928 BC011936 AAH11936 DQ893391 ABM84317 DQ896713 ABM87712 HY174042 NM_025205 NP_079481
Function Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. May be part of a complex containing NF2/merlin that participates in cellular signaling to the actin cytoskeleton downstream of tyrosine kinase signaling pathways. {ECO:0000269|PubMed:15467741}.
Subcellular Location Nucleus {ECO:0000269|PubMed:15467741}. Cytoplasm {ECO:0000269|PubMed:15467741}. Membrane {ECO:0000269|PubMed:15467741}; Peripheral membrane protein {ECO:0000269|PubMed:15467741}. Note=According to PubMed:15467741, it is cytoplasmic and mainly membrane-associated.
Tissue Specificity Widely expressed. Highly expressed in vascular tissues such as placenta, testis and liver. {ECO:0000269|PubMed:15467741}.

MED28 / Magicin Antibody Blocking Peptide - LS-E30543 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 50 µg

MED28 Blocking Peptide - NBP1-76931PEP from Novus Biologicals

Category Peptide
Prices $129.00
Sizes 50 µg
Species Human
Western Blot: MED28 Peptide [NBP1-76931PEP] - blocks the antibody activity completely in Western blot by incubating the peptide with equal volume of antibody for 30 min at 37C.

MED28-Antibody-Center-Blocking-peptide - BP12901c from Abgent, a WuXi AppTec company

Category Peptide
Prices $80.00
Sizes 100 µg

MED28-Antibody-C-term-Blocking-Peptide - BP6873b from Abgent, a WuXi AppTec company

Category Peptide
Prices $80.00
Sizes 100 µg

MED28 Peptide - GTX85388-PEP from GeneTex

Category Peptide
Prices $149.00
Sizes 50 μg
Species Human
Anti-MED28 Peptide used in Western blot. GTX85388-PEP

MED28 Blocking Peptide - abx161157 from Abbexa

Category Peptide
Species Human, Mouse, Rat, Chicken, Zebrafish

MED28 Control Peptide - AP30555CP-N from Acris Antibodies

Category Peptide
Prices $135.00
Sizes 50 µg

MED28 Peptide - 4731P from ProSci

Category Peptide
Species Human
Western blot analysis of MED28 in human brain tissue lysate with MED28 antibody at 1 μg/mL in (A) the absence and (B) the presence of blocking peptide.

MED28 fusion protein - Ag9230 from Proteintech Group

Category Protein
Prices $199.00
Sizes 50 μg
Source E. coli -derived, PET28a
Species Human

MED28 fusion protein - Ag9327 from Proteintech Group

Category Protein
Prices $199.00
Sizes 50 μg
Source E. coli -derived, PGEX-4T
Species Human

Recombinant Human MED28, His-tagged - MED28-812H from Creative Biomart

Category Protein
Source E.coli
Species Human

MED28 Blocking Peptide - CBP3656 from Cohesion Biosciences

Category Peptide
Prices $100.00, $300.00
Sizes 1 mg, 5 mg
Species Human, Mouse, Rat, Bovine, Zebrafish

Recombinant Human Mediator of RNA polymerase II transcription subunit 28(MED28) - CSB-YP863955HU CSB-EP863955HU CSB-BP863955HU CSB-MP863955HU from Cusabio

Category Protein
Source Yeast or E.coli or Baculovirus or Mammalian cell
Species Human

MED28 (full length, N-term HIS tag) - TP760745 from Acris Antibodies

Category Protein
Prices $199.00
Sizes 50 µg
Source E. coli
Species Human
MED28

MED28 Recombinant Protein Antigen - NBP2-38271PEP from Novus Biologicals

Category Protein
Prices $199.00
Sizes 100 µl
Source E.coli
Species Human

MED28 Recombinant Protein Antigen - NBP1-85104PEP from Novus Biologicals

Category Protein
Prices $199.00
Sizes 100 µl
Source E.coli
Species Human

MED28 Peptide, Human - M34GP09373H from Creative Peptides

Category Peptide
Source Synthetic.
Species Human

Mediator of RNA polymerase II transcription subunit 28 (MED28), Recombinant Protein - MBS1378599 from MyBioSource

Category Protein
Prices $930.00, $930.00, $1,155.00, $1,155.00, $1,390.00, $1,390.00, $1,845.00, $1,845.00
Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell)
Source E Coli or Yeast or Baculovirus or Mammalian Cell

Mediator of RNA polymerase II transcription subunit 28 (MED28), Recombinant Protein - MBS1429946 from MyBioSource

Category Protein
Prices $925.00, $925.00, $1,145.00, $1,145.00, $1,375.00, $1,375.00, $1,830.00, $1,830.00
Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell)
Source E Coli or Yeast or Baculovirus or Mammalian Cell
Species Human

MED28 peptide - orb234531 from Biorbyt

Category Peptide
Search more