TCL1A

Gene Symbol TCL1A
Entrez Gene 8115
Alt Symbol TCL1
Species Human
Gene Type protein-coding
Description T-cell leukemia/lymphoma 1A
Other Description T-cell leukemia/lymphoma protein 1A|T-cell lymphoma-1|oncogene TCL-1|oncogene TCL1|protein p14 TCL1
Swissprots Q6IBK7 P56279
Accessions CDL93495 EAW81622 EAW81623 P56279 BC003574 AAH03574 BC005831 AAH05831 BC009502 BC009891 BC014024 AAH14024 BG718395 BU602054 CR456796 CAG33077 DQ892500 ABM83426 DQ895713 ABM86639 X82240 CAA57708 NM_001098725 NP_001092195 NM_021966 NP_068801 NR_049726
Function Enhances the phosphorylation and activation of AKT1, AKT2 and AKT3. Promotes nuclear translocation of AKT1. Enhances cell proliferation, stabilizes mitochondrial membrane potential and promotes cell survival. {ECO:0000269|PubMed:10716693, ECO:0000269|PubMed:10983986, ECO:0000269|PubMed:11707444, ECO:0000269|PubMed:11839817}.
Subcellular Location Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}. Microsome {ECO:0000269|PubMed:7987816}. Endoplasmic reticulum {ECO:0000269|PubMed:7987816}. Note=Microsomal fraction.
Tissue Specificity Restricted in the T-cell lineage to immature thymocytes and activated peripheral lymphocytes. Preferentially expressed early in T- and B-lymphocyte differentiation.
Top Pathways PI3K-Akt signaling pathway

TCL1A-Over-expression-Lysate - LY15140a from Abgent, a WuXi AppTec company

Category Cell Lysate
Prices $325.00
Sizes 100 µg
Western blot analysis of his-tag TCL1A (arrow) using his tag antibody. 293T cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the TCL1A gene‘

TCL1A 293T Cell Transient Overexpression Lysate(Denatured) - H00008115-T01 from Acris Antibodies

Category Cell Lysate
Prices $320.00
Sizes 100 µl

TCL1A 293 Cell Lysate - 405900 from ABBIOTEC

Category Cell Lysate
Prices $392.00
Sizes 100 µg
Disease Cancer

TCL1A Overexpression Lysate (Denatured) - H00008115-T01 from Novus Biologicals

Category Cell Lysate
Prices $279.00
Sizes 100 µl
TCL1A transfected lysate.

TCL1A Overexpression Lysate (Native) - NBP2-06492 from Novus Biologicals

Category Cell Lysate
Prices $329.00
Sizes 100 µg
Western Blot: TCL1 Overexpression Lysate (Adult Normal) [NBP2-06492] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for TCL1.

TCL-1A (h): 293T Lysate - sc-176661 from Santa Cruz Biotechnology

Category Cell Lysate
Prices $205.00
Sizes 100 µg/200 µl
Species Human

TCL-1A (h2): 293T Lysate - sc-159145 from Santa Cruz Biotechnology

Category Cell Lysate
Prices $205.00
Sizes 100 µg/200 µl
Species Human

TCL1A Over-expression Lysate Product - GWB-2F5F33 from Genway Biotech

Category Cell Lysate
Prices $346.00
Sizes 100 µg
Species Human

TCL1A Overexpression Lysate (Native) - NBP2-11427 from Novus Biologicals

Category Cell Lysate
Prices $329.00
Sizes 100 µg
Western Blot: TCL1 Overexpression Lysate (Adult Normal) [NBP2-11427] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for TCL1.

TCL1A Overexpression Lysate (Native) - NBP2-10915 from Novus Biologicals

Category Cell Lysate
Prices $329.00
Sizes 100 µg

Panoply™ Human TCL1A Knockdown Stable Cell Line - CSC-DC015735 from Creative biogene

Category Cell Line
Species Human
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