TCL1A

Gene Symbol TCL1A
Entrez Gene 8115
Alt Symbol TCL1
Species Human
Gene Type protein-coding
Description T-cell leukemia/lymphoma 1A
Other Description T-cell leukemia/lymphoma protein 1A|T-cell lymphoma-1|oncogene TCL-1|oncogene TCL1|protein p14 TCL1
Swissprots Q6IBK7 P56279
Accessions CDL93495 EAW81622 EAW81623 P56279 BC003574 AAH03574 BC005831 AAH05831 BC009502 BC009891 BC014024 AAH14024 BG718395 BU602054 CR456796 CAG33077 DQ892500 ABM83426 DQ895713 ABM86639 X82240 CAA57708 NM_001098725 NP_001092195 NM_021966 NP_068801 NR_049726
Function Enhances the phosphorylation and activation of AKT1, AKT2 and AKT3. Promotes nuclear translocation of AKT1. Enhances cell proliferation, stabilizes mitochondrial membrane potential and promotes cell survival. {ECO:0000269|PubMed:10716693, ECO:0000269|PubMed:10983986, ECO:0000269|PubMed:11707444, ECO:0000269|PubMed:11839817}.
Subcellular Location Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}. Microsome {ECO:0000269|PubMed:7987816}. Endoplasmic reticulum {ECO:0000269|PubMed:7987816}. Note=Microsomal fraction.
Tissue Specificity Restricted in the T-cell lineage to immature thymocytes and activated peripheral lymphocytes. Preferentially expressed early in T- and B-lymphocyte differentiation.
Top Pathways PI3K-Akt signaling pathway

TCL-1A CRISPR/Cas9 KO Plasmid (h) - sc-402028 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

TCL-1A HDR Plasmid (h) - sc-402028-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TCL-1A Double Nickase Plasmid (h) - sc-402028-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TCL-1A Double Nickase Plasmid (h2) - sc-402028-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TCL-1A CRISPR Activation Plasmid (h) - sc-402028-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

TCL-1A CRISPR Activation Plasmid (h2) - sc-402028-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

TCL-1A Lentiviral Activation Particles (h) - sc-402028-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TCL-1A Lentiviral Activation Particles (h2) - sc-402028-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TCL-1A siRNA (h) - sc-42988 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

TCL-1A shRNA Plasmid (h) - sc-42988-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

TCL-1A shRNA (h) Lentiviral Particles - sc-42988-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

TCL1A RNAi - H00008115-R01 from Novus Biologicals

Category siRNA
Prices $409.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU055641 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN21156 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND21156 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR07063 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr07063

TCL1A siRNA (Human) - CRH5373 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

TCL1A RNAi - H00008115-R02 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

TCL1A - MBS8234745 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human TCL1A(NM_021966.2) - SHL062670 from Creative biogene

Category siRNA
Species Reactivities Human

Human TCL1A siRNA - orb265875 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

TCL1A shRNA Plasmid (Human) - CHH5373 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

TCL1A miRNA 3'UTR clone - MiUTR1H-10289 from Creative biogene

Species Reactivities Human

TCL1A miRNA 3'UTR clone - MiUTR3H-02189 from Creative biogene

Species Reactivities Human
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