TCL1A

Gene Symbol	TCL1A
Entrez Gene	8115
Alt Symbol	TCL1
Species	Human
Gene Type	protein-coding
Description	T-cell leukemia/lymphoma 1A
Other Description	T-cell leukemia/lymphoma protein 1A|T-cell lymphoma-1|oncogene TCL-1|oncogene TCL1|protein p14 TCL1
Swissprots	Q6IBK7 P56279
Accessions	CDL93495 EAW81622 EAW81623 P56279 BC003574 AAH03574 BC005831 AAH05831 BC009502 BC009891 BC014024 AAH14024 BG718395 BU602054 CR456796 CAG33077 DQ892500 ABM83426 DQ895713 ABM86639 X82240 CAA57708 NM_001098725 NP_001092195 NM_021966 NP_068801 NR_049726
Function	Enhances the phosphorylation and activation of AKT1, AKT2 and AKT3. Promotes nuclear translocation of AKT1. Enhances cell proliferation, stabilizes mitochondrial membrane potential and promotes cell survival. {ECO:0000269|PubMed:10716693, ECO:0000269|PubMed:10983986, ECO:0000269|PubMed:11707444, ECO:0000269|PubMed:11839817}.
Subcellular Location	Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}. Microsome {ECO:0000269|PubMed:7987816}. Endoplasmic reticulum {ECO:0000269|PubMed:7987816}. Note=Microsomal fraction.
Tissue Specificity	Restricted in the T-cell lineage to immature thymocytes and activated peripheral lymphocytes. Preferentially expressed early in T- and B-lymphocyte differentiation.
Top Pathways	PI3K-Akt signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human Tcl1 full length protein - ab87690 from Abcam Category Protein Source E. coli Species Human

Human Tcl1 peptide - ab38395 from Abcam Category Peptide

Human Tcl1 peptide - ab38396 from Abcam Category Peptide

TCL1A Partial Recombinant Protein - H00008115-Q02 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

TCL1A Partial Recombinant Protein - H00008115-Q01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Recombinant Human TCL1A Protein - NBP1-30239 from Novus Biologicals Category Protein Prices $229.00 Sizes 100 µg Species Human

TCL1A Protein - GTX109313-pro from GeneTex Category Protein Prices $299.00 Sizes 25 μg Source E. coli Species Human

TCL1A blocking peptide - GTX88906-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human

TCL1A Protein (OPPA02237) - OPPA02237 from Aviva Systems Biology Category Protein Prices $100.00 Sizes 10 µg Source E. Coli

Human T-cell Leukemia/Lymphoma 1A protein - orb81412 from Biorbyt Category Protein Prices $230.00, $442.00 Sizes 10 μg, 50 μg Source E.coli Species Human

Human TCL1A protein (His Tag) - orb139720 from Biorbyt Category Protein Prices $238.00, $434.00 Sizes 20 μg, 100 μg Source E. coli Species Human

TCL1A Blocking Peptide - 33R-5631 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

TCL1A protein - 30R-1391 from Fitzgerald Category Protein Prices $180.00 Sizes 100 µg Source E.coli

Human TCL1A Protein - abx069248 from Abbexa Category Protein Source E.coli Species Human

Tcl1 Peptide - AC21-1139-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

TCL1A / TCL1 (1-114) - AR09274PU-L from Acris Antibodies Category Protein Prices $585.00 Sizes 500 µg Source E. coli Species Human

TCL1A / TCL1 (1-114) - AR09274PU-N from Acris Antibodies Category Protein Prices $270.00 Sizes 100 µg Source E. coli Species Human

TCL1A / TCL1 - H00008115-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

TCL1A / TCL1 - H00008115-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

TCL1A / TCL1 - H00008115-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

TCL1A / TCL1 - H00008115-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

TCL1A / TCL1 - H00008115-Q02 from Acris Antibodies Category Protein Prices $370.00 Sizes 10 µg Species Human

TCL1A / TCL1 - H00008115-Q02-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

TCL1A / TCL1 - H00008115-Q02-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

T-cell Leukemia/Lymphoma 1A, Human Recombinant - 228-13182-1 from RayBiotech Category Protein Prices $118.00 Sizes 1 µg Species Human

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