PEG10

Gene Symbol	PEG10
Entrez Gene	23089
Alt Symbol	EDR, HB-1, MEF3L, Mar2, Mart2, RGAG3
Species	Human
Gene Type	protein-coding
Description	paternally expressed 10
Other Description	MEF3 like 1|embryonal carcinoma differentiation regulated|mammalian retrotransposon-derived protein 2|myelin expression factor 3-like protein 1|paternally expressed gene 10 protein|retrotransposon gag domain-containing protein 3|retrotransposon-derived gag-like polyprotein|retrotransposon-derived protein PEG10|ty3/Gypsy-like protein
Swissprots	Q96A68 Q9UPV1 Q86TG7
Accessions	AAS07484 EAW76781 Q86TG7 AB028974 BAA83003 AB049150 BAB68387 AB049834 BAB43951 AF038197 AF216076 AK025529 AK299837 BAG61702 AL589326 BC015448 BC050659 AAH50659 BP250746 DA297295 DA683494 R17262 R79712 NM_001040152 NP_001035242 NM_001172437 NP_001165908 NM_001172438 NP_001165909 NM_001184961 NP_001171890 NM_001184962 NP_001171891 NM_015068 NP_055883
Function	Prevents apoptosis in hepatocellular carcinoma (HCC) cells through interaction with SIAH1, a mediator of apoptosis. May also have a role in cell growth promotion and hepatoma formation. Inhibits the TGF-beta signaling by interacting with the TGF-beta receptor ALK1. When overexpressed, induces the formation of cellular extension, such as filipodia in association with ALK1. Involved at the immediate early stage of adipocyte differentiation (By similarity). May bind to the 5'-GCCTGTCTTT-3' DNA sequence of the MB1 domain in the myelin basic protein (MBP) promoter (By similarity). {ECO:0000250}.
Subcellular Location	Nucleus. Cytoplasm. Note=Detected predominantly in the cytoplasm of breast and prostate carcinomas, in hepatocellular carcinoma (HCC) and B-cell chronic lymphocytic leukemia (B-CLL) cells and in the Hep-G2 cell line. Colocalized with ALK1.
Tissue Specificity	Expressed in the cytotrophoblast layer but not in the overlying syncytiotrophoblast of the placenta. Expressed in prostate and breast carcinomas but not in normal breast and prostate epithelial cells. Expressed in the Hep-G2 cell line (at protein level). Expressed in brain, liver, spleen, kidney, thymus, lung, ovary, testis, reactive lymph node, skeletal muscle, adipose tissue and placenta. Expressed in pancreatic and hepatocellular carcinomas (HCC). {ECO:0000269|PubMed:11318613, ECO:0000269|PubMed:12810624, ECO:0000269|PubMed:15611116, ECO:0000269|PubMed:16423995, ECO:0000269|PubMed:17621626}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Retrotransposon-derived protein PEG10 (PEG10), Human, ELISA Kit - CSB-EL017772HU from ARP American Research Products Category ELISA Kit Prices $495.00, $695.00, $696.00, $699.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t

Retrotransposon-derived protein PEG10, PEG10, Human, ELISA Kit - E3142h from ARP American Research Products Category ELISA Kit Prices $660.00 Sizes 96 t Range 0.312-20 ng/mL.

paternally expressed 10, ELISA Kit - MBS929498 from MyBioSource Category ELISA Kit Prices $250.00, $495.00, $710.00, $2,705.00, $5,145.00 Sizes 24 -strip-wells (Limit 1), 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity The minimum detectable dose of human PEG10 is typically less than 4.69 pg/ml. The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined the mean O.D value of 20 replicates of the zero standard added by their three standard deviations. Range 18.75 pg/ml -1200 pg/ml.

Human Retrotransposon-derived protein PEG10(PEG10) ELISA kit - CSB-EL017772HU from Cusabio Category ELISA Kit Sensitivity 4.69 pg/ml Range 18.75 pg/ml-1200 pg/ml

Mouse EDR / PEG10 ELISA Kit (Custom ELISA) - LS-F19837 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity To be determined Range 0.312-20 ng/ml

Human EDR / PEG10 ELISA Kit (Sandwich ELISA) - LS-F13383 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity 0.312 Range 0.312-20 ng/ml

PEG10 - EKH4514 from Nordic BioSite Sensitivity 0.188ng/ml Range 0.312-20ng/ml

PEG10 ELISA Kit (Human) : 96 Wells (OKEH01691) - OKEH01691 from Aviva Systems Biology Category ELISA Kit Prices $450.00 Sizes 96 wells Sensitivity < 0.19 ng/mL Range 0.312 - 20 ng/mL

Human PEG10 ELISA Kit - E028368 from Biobool Category ELISA Kit Sensitivity The minimum detectable dose of human PEG10 is typically less than 4.69 pg/ml. The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined the me

Human Retrotransposon-derived protein PEG10 ELISA Kit - EK4573 from Signalway Antibody Category ELISA Kit Prices $659.00 Sizes 1x96t Sensitivity less than 0.078ng/mL Range 0.156-10 ng/mL

anti-PEG10 antibody - ARG54121 from Arigo Biolaboratories Category ELISA Kit

Human Retrotransposon-derived protein PEG10 (PEG10) ELISA Kit - AE28041HU from ARP American Research Products Category ELISA Kit Prices $549.00 Sizes 96 t Sensitivity 4.69 pg/mL Range 18.75-1200 pg/mL

Retrotransposon-derived protein PEG10, ELISA Kit - MBS760102 from MyBioSource Category ELISA Kit Prices $295.00, $390.00, $1,615.00, $3,015.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.188ng/ml Range 0.312-20ng/ml

Retrotransposon-derived protein PEG10, ELISA Kit - MBS2880101 from MyBioSource Category ELISA Kit Prices $430.00, $570.00, $2,515.00, $4,520.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Range 0.312-20 ng/mL.

Retrotransposon-derived protein PEG10, ELISA Kit - MBS9428399 from MyBioSource Category ELISA Kit Prices $605.00 Sizes 96 tests Sensitivity Less than 0.19ng/mL Range 0.312-20 ng/mL.

Human EDR / PEG10 ELISA Kit (Sandwich ELISA) - LS-F33547 from LifeSpan Bioscience Category ELISA Kit Sensitivity 0.188 Range 0.312-20 ng/ml

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