PEG10

Gene Symbol	PEG10
Entrez Gene	23089
Alt Symbol	EDR, HB-1, MEF3L, Mar2, Mart2, RGAG3
Species	Human
Gene Type	protein-coding
Description	paternally expressed 10
Other Description	MEF3 like 1|embryonal carcinoma differentiation regulated|mammalian retrotransposon-derived protein 2|myelin expression factor 3-like protein 1|paternally expressed gene 10 protein|retrotransposon gag domain-containing protein 3|retrotransposon-derived gag-like polyprotein|retrotransposon-derived protein PEG10|ty3/Gypsy-like protein
Swissprots	Q96A68 Q9UPV1 Q86TG7
Accessions	AAS07484 EAW76781 Q86TG7 AB028974 BAA83003 AB049150 BAB68387 AB049834 BAB43951 AF038197 AF216076 AK025529 AK299837 BAG61702 AL589326 BC015448 BC050659 AAH50659 BP250746 DA297295 DA683494 R17262 R79712 NM_001040152 NP_001035242 NM_001172437 NP_001165908 NM_001172438 NP_001165909 NM_001184961 NP_001171890 NM_001184962 NP_001171891 NM_015068 NP_055883
Function	Prevents apoptosis in hepatocellular carcinoma (HCC) cells through interaction with SIAH1, a mediator of apoptosis. May also have a role in cell growth promotion and hepatoma formation. Inhibits the TGF-beta signaling by interacting with the TGF-beta receptor ALK1. When overexpressed, induces the formation of cellular extension, such as filipodia in association with ALK1. Involved at the immediate early stage of adipocyte differentiation (By similarity). May bind to the 5'-GCCTGTCTTT-3' DNA sequence of the MB1 domain in the myelin basic protein (MBP) promoter (By similarity). {ECO:0000250}.
Subcellular Location	Nucleus. Cytoplasm. Note=Detected predominantly in the cytoplasm of breast and prostate carcinomas, in hepatocellular carcinoma (HCC) and B-cell chronic lymphocytic leukemia (B-CLL) cells and in the Hep-G2 cell line. Colocalized with ALK1.
Tissue Specificity	Expressed in the cytotrophoblast layer but not in the overlying syncytiotrophoblast of the placenta. Expressed in prostate and breast carcinomas but not in normal breast and prostate epithelial cells. Expressed in the Hep-G2 cell line (at protein level). Expressed in brain, liver, spleen, kidney, thymus, lung, ovary, testis, reactive lymph node, skeletal muscle, adipose tissue and placenta. Expressed in pancreatic and hepatocellular carcinomas (HCC). {ECO:0000269|PubMed:11318613, ECO:0000269|PubMed:12810624, ECO:0000269|PubMed:15611116, ECO:0000269|PubMed:16423995, ECO:0000269|PubMed:17621626}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Peg10 (C-7) - sc-365675 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Mouse Clonality Monoclonal

Peg10 (H-160) - sc-68899 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Rabbit Clonality Polyclonal

Peg10 (Q-20) - sc-104592 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

Peg10 (M-200) - sc-68898 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Rabbit Clonality Polyclonal

Anti-PEG10 antibody - ab182769 from Abcam Prices $376.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-PEG10 antibody - ab151782 from Abcam Prices $376.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-PEG10 antibody - ab68780 from Abcam Prices $376.00 Sizes 50 µg Host Mouse Clonality Polyclonal

Anti-PEG10 antibody - ab112593 from Abcam Prices $376.00 Sizes 400 µl Host Rabbit Clonality Polyclonal

Anti-PEG10 antibody - ab126793 from Abcam Prices $370.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-PEG10 antibody [1B1C4] - ab81608 from Abcam Prices $378.00 Sizes 100 µl Host Mouse Clonality Monoclonal Clone 1B1C4

Anti-PEG10 antibody [1D9-6] - ab126813 from Abcam Prices $370.00 Sizes 100 µg Host Mouse Clonality Monoclonal Clone 1D9-6

Anti-PEG10 antibody [1E2-F12-C12] - ab131194 from Abcam Prices $378.00 Sizes 100 µg Host Mouse Clonality Monoclonal Clone 1E2-F12-C12

Anti-PEG10 antibody [4C10A7] - ab81609 from Abcam Host Mouse Clonality Monoclonal Clone 4C10A7

Anti-PEG10 antibody [EPR8156(2)] - ab181249 from Abcam Prices $376.00 Sizes 100 µl Host Rabbit Clonality Monoclonal Clone EPR8156(2)

Anti-EDR / PEG10 Antibody (aa1-30, AP) - LS-C266036 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-EDR / PEG10 Antibody (aa1-30, APC) - LS-C266037 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-EDR / PEG10 Antibody (aa1-30, Biotin) - LS-C266038 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-EDR / PEG10 Antibody (aa1-30, FITC) - LS-C266039 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-EDR / PEG10 Antibody (Biotin) - LS-C317706 from LifeSpan Bioscience Prices $305.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-EDR / PEG10 Antibody (aa1-30, Azide-free, HRP) - LS-C266040 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-EDR / PEG10 Antibody (FITC) - LS-C317709 from LifeSpan Bioscience Prices $305.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-EDR / PEG10 Antibody (aa1-30, PE) - LS-C284531 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-EDR / PEG10 Antibody - LS-C317712 from LifeSpan Bioscience Prices $305.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-EDR / PEG10 Antibody (HRP) - LS-C317711 from LifeSpan Bioscience Prices $305.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-EDR / PEG10 Antibody (aa324-373) - LS-C187185 from LifeSpan Bioscience Prices $365.00 Sizes 50 µg Host Rabbit Clonality Polyclonal

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