DLL4

Gene Symbol	DLL4
Entrez Gene	54567
Alt Symbol	hdelta2
Species	Human
Gene Type	protein-coding
Description	delta-like 4 (Drosophila)
Other Description	delta 4|delta ligand 4|delta-like 4 homolog|delta-like 4 protein|delta-like protein 4|delta4|drosophila Delta homolog 4|notch ligand DLL4|notch ligand delta-2
Swissprots	Q9NR61 Q3KP23 Q9NQT9
Accessions	EAW92466 Q9NR61 AB036931 BAB16085 AB043894 BAB18581 AF253468 AAF76427 AF279305 AAF81912 AI478830 AK308755 AK313831 BAG36565 AY358894 AAQ89253 BC106950 AAI06951 BI820351 DA089757 NM_019074 NP_061947
Function	Involved in the Notch signaling pathway as Notch ligand. Activates NOTCH1 and NOTCH4. Involved in angiogenesis; negatively regulates endothelial cell proliferation and migration and angiogenic sprouting. Essential for retinal progenitor proliferation is required for suppressing rod fates in late retinal progenitors as well as for proper generation of other retinal cell types. During spinal cord neurogenesis, inhibits V2a interneuron fate. {ECO:0000269|PubMed:17728344, ECO:0000269|PubMed:20616313}.
Subcellular Location	Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.
Tissue Specificity	Expressed in vascular endothelium.
Top Pathways	Notch signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Mouse DLL4 ELISA Kit (Sandwich ELISA) - LS-F2930 from LifeSpan Bioscience Category ELISA Kit Prices $530.00 Sizes 1 plate Sensitivity 10 pg/ml Range 156-10000 pg/ml

Mouse DLL4 ELISA Kit (Custom ELISA) - LS-F378 from LifeSpan Bioscience Category ELISA Kit Prices $670.00, $1,190.00, $2,570.00 Sizes 1 plate, 2 plate, 5 plate Sensitivity To be determined Range 156-10000 pg/ml

Human DLL4 ELISA Kit (Sandwich ELISA) - LS-F7252 from LifeSpan Bioscience Category ELISA Kit Prices $720.00 Sizes 1 plate Sensitivity 0.054 ng/ml Range 156-10000 pg/ml

Rat DLL4 ELISA Kit (Sandwich ELISA) - LS-F8044 from LifeSpan Bioscience Category ELISA Kit Prices $780.00 Sizes 1 plate Sensitivity 0.068 ng/ml Range 156-10000 pg/ml

Mouse DLL4 DuoSet ELISA - DY1389 from R&D Systems Category ELISA Kit Prices $649.00 Sizes 1 kit (for 15 Plates) Range 312.50 - 10,000 pg/mL

Delta Like Protein 4 (dLL4), Human, ELISA Kit - SEJ256Hu from ARP American Research Products Category ELISA Kit Prices $720.00 Sizes 96 t Sensitivity 0.063ng/mL Range 0.156-10ng/mL

Delta-like protein 4 (DLL4), Human, ELISA Kit - CSB-EL006949HU from ARP American Research Products Category ELISA Kit Prices $495.00, $695.00, $696.00, $699.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t Sensitivity 5.8 pg/ml Range 23.5 pg/ml-1500 pg/ml

Delta-like protein 4, DLL4, Human, ELISA Kit - E13896h from ARP American Research Products Category ELISA Kit Prices $596.00 Sizes 96 t

Delta Like Protein 4 (dLL4), ELISA Kit - MBS9301347 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Delta Like Protein 4 (dLL4), ELISA Kit - MBS9300587 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Delta Like Protein 4 (dLL4), ELISA Kit - MBS2024394 from MyBioSource Category ELISA Kit Prices $405.00, $605.00, $820.00, $3,375.00, $6,125.00 Sizes 24 -strip-wells, 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity The minimum detectable dose of rat dLL4 is typically less than 0.068ng/mL. The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined by adding two standard deviations to the mean optical density value of twenty zero standard replicates and calculating the corresponding concentration. Range 0.156-10ng/mL

Delta Like Protein 4 (dLL4), ELISA Kit - MBS2023134 from MyBioSource Category ELISA Kit Prices $380.00, $565.00, $765.00, $3,130.00, $5,670.00 Sizes 24 -strip-wells, 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.054ng/mL. Range 0.156-10ng/mL. The standard curve concentrations used for the ELISA's were 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.312ng/mL, 0.156ng/mL.

delta-like 4 (Drosophila) , ELISA Kit - MBS942396 from MyBioSource Category ELISA Kit Prices $250.00, $495.00, $710.00, $2,705.00, $5,145.00 Sizes 24 -strip-wells (Limit 1), 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 5.8 pg/ml Range 23.5 pg/ml-1500 pg/ml

Mouse DLL4 ELISA Pair Set - SEK50640-5 from Sino Biological Category ELISA Kit Prices $350.00, $350.00 Sizes 5 plates, 15 plates

Human DLL4 ELISA Pair Set - SEK10171-5 from Sino Biological Category ELISA Kit Prices $350.00, $350.00 Sizes 5 plates, 15 plates

ELISA Kit for Delta Like Protein 4 (dLL4) - SEJ256Hu from Uscn Life Science Inc. Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.054ng/mL. Range 0.156-10ng/mL The standard curve concentrations used for the ELISA’s were 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL, 0.156ng/mL

ELISA Kit for Delta Like Protein 4 (dLL4) - SEJ256Ra from Uscn Life Science Inc. Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.068ng/mL. Range 0.156-10ng/mL The standard curve concentrations used for the ELISA’s were 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL, 0.156ng/mL

Human Delta-like protein 4(DLL4) ELISA kit - CSB-EL006949HU from Cusabio Category ELISA Kit Sensitivity 5.8 pg/ml. Range 23.5 pg/ml-1500 pg/ml

ELISA Kit for Delta Like Protein 4 (dLL4) - SEJ256Hu from Cloud-clone Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.054ng/mL. Range 0.156-10ng/mL The standard curve concentrations used for the ELISA's were 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL, 0.156ng/mL

Human DLL4 ELISA Kit (Sandwich ELISA) - LS-F17072 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity 0.156 ng/ml Range 156-10000 pg/ml

Mouse DLL4 ELISA Kit (Custom ELISA) - LS-F17071 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity To be determined Range 156-10000 pg/ml

Custom Human DLL4 ELISA - ELH-DLL4 from RayBiotech Category ELISA Kit Prices $615.00, $1,107.00, $2,460.00 Sizes 1 plate kit, 2 plate kit, 5 plate kit

Mouse DLL4 ELISA Kit (Sandwich ELISA) - LS-F24793 from LifeSpan Bioscience Category ELISA Kit Prices $550.00 Sizes 1 plate Sensitivity 10 pg/ml Range 156-10000 pg/ml

Delta Like Protein 4 (dLL4), Human, ELISA Kit - DL-dLL4-Hu from ARP American Research Products Category ELISA Kit Prices $655.00 Sizes 96 t Range 0.156-10 ng/mL

Human DLL4 ELISA Kit - DEIA-XY2203 from Creative Diagnostics Category ELISA Kit Sensitivity 15 pg/mL Range 31-2000 pg/mL

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