Gene Symbol | TRMT5 |
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Entrez Gene | 57570 |
Alt Symbol | KIAA1393, TRM5 |
Species | Human |
Gene Type | protein-coding |
Description | tRNA methyltransferase 5 |
Other Description | M1G-methyltransferase|TRM5 tRNA methyltransferase 5 homolog|tRNA (guanine(37)-N1)-methyltransferase|tRNA (guanine-N(1)-)-methyltransferase|tRNA [GM37] methyltransferase|tRNA-N1G37 methyltransferase |
Swissprots | B2RN19 Q9P2F4 Q32P41 |
Accessions | EAW80792 Q32P41 AB037814 BAA92631 AK293158 BAG56703 BC029638 BC063551 BC108284 AAI08285 BC136606 AAI36607 BC136607 AAI36608 BQ050607 DB448202 DC370229 XM_005267916 XP_005267973 XM_011537017 XP_011535319 NM_020810 NP_065861 |
Function | Specifically methylates the N1 position of guanosine-37 in various cytoplasmic and mitochondrial tRNAs. Methylation is not dependent on the nature of the nucleoside 5' of the target nucleoside. This is the first step in the biosynthesis of wybutosine (yW), a modified base adjacent to the anticodon of tRNAs and required for accurate decoding. |
Subcellular Location | Mitochondrion matrix {ECO:0000255|HAMAP- Rule:MF_03152}. Nucleus {ECO:0000255|HAMAP-Rule:MF_03152}. Cytoplasm {ECO:0000255|HAMAP-Rule:MF_03152}. Note=Predominantly in the mitochondria and in the nucleus. {ECO:0000255|HAMAP- Rule:MF_03152}. |
Anti-TRMT5 antibody - ab83379 from Abcam
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Anti-TRMT5 antibody - ab118666 from Abcam
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Anti-TRMT5 Antibody (aa256-305) - LS-C145697 from LifeSpan Bioscience
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Anti-TRMT5 Antibody (C-Terminus) - LS-C102324 from LifeSpan Bioscience
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TRMT5 Antibody - NBP1-82909 from Novus Biologicals
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TRMT5 Antibody - NBP1-52876 from Novus Biologicals
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Anti-TRMT5 antibody produced in rabbit - SAB2102581 from Sigma-Aldrich
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Anti-TRMT5 antibody produced in rabbit - HPA000943 from Sigma-Aldrich
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TRMT5 antibody - middle region (ARP48868_P050) - ARP48868_P050 from Aviva Systems Biology
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TRMT5 antibody - orb186380 from Biorbyt
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TRMT5 antibody - 70R-2000 from Fitzgerald
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TRMT5 antibody - 70R-21006 from Fitzgerald
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TRMT5 antibody - 18255-1-AP from Acris Antibodies
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TRMT5 Antibody - 26-357 from ProSci
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TRMT5 antibody - 18255-1-AP from Proteintech Group
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TRMT5 Antibody - GWB-MR305H from Genway Biotech
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TRM5 tRNA methyltransferase 5 homolog, Polyclonal Antibody - MBS711797 from MyBioSource
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TRMT5, Polyclonal Antibody - MBS5302027 from MyBioSource
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TRMT5, Polyclonal Antibody - MBS5301287 from MyBioSource
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TRMT5 (C-16) - sc-244496 from Santa Cruz Biotechnology
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TRMT5 (P-18) - sc-244495 from Santa Cruz Biotechnology
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TRMT5 antibody (FITC) - orb190694 from Biorbyt
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TRMT5 antibody - TA346865 from Acris Antibodies
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anti-TRMT5 antibody - A009007 from Biobool
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TRMT5 antibody - middle region : Biotin (ARP48868_P050-Biotin) - ARP48868_P050-Biotin from Aviva Systems Biology
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