SLA

Gene Symbol SLA
Entrez Gene 6503
Alt Symbol SLA1, SLAP
Species Human
Gene Type protein-coding
Description Src-like-adaptor
Other Description SLAP-1|hSLAP|src-like-adapter|src-like-adapter protein 1
Swissprots B7Z4L6 Q6FI01 Q13239 Q9UMQ8 B7Z4J2
Accessions CAV30731 CBX47476 CBX47477 CBX47478 EAW92159 Q13239 AJ238591 CAB53536 AK297423 BAH12578 AK297519 BAH12602 AK309401 AK310092 AK310108 AK310115 AK311010 AK312584 BAG35478 AW137142 BC007042 AAH07042 BT019994 AAV38797 BX648382 CR536537 CAG38774 D89077 BAA13758 DA483212 DA522819 DA999385 DB265860 DC313073 EU831422 ACE87109 EU831515 ACE86434 U30473 AAC50357 U44403 AAC27662 XM_011517227 XP_011515529 XM_011517228 XP_011515530 NM_001045556 NP_001039021 NM_001045557 NP_001039022 NM_001282964 NP_001269893 NM_001282965 NP_001269894 NM_006748 NP_006739
Function Adapter protein, which negatively regulates T-cell receptor (TCR) signaling. Inhibits T-cell antigen-receptor induced activation of nuclear factor of activated T-cells. Involved in the negative regulation of positive selection and mitosis of T-cells. May act by linking signaling proteins such as ZAP70 with CBL, leading to a CBL dependent degradation of signaling proteins. {ECO:0000269|PubMed:10449770, ECO:0000269|PubMed:11696592}.
Subcellular Location Cytoplasm {ECO:0000250}. Endosome {ECO:0000250}. Note=Colocalizes with endosomes. {ECO:0000250}.
Tissue Specificity Expressed in lung and fetal brain. Weakly expressed in heart, adult brain, placenta, liver, skeletal muscle, kidney and pancreas. {ECO:0000269|PubMed:9660183}.

SLA-Over-expression-Lysate - LY13685a from Abgent, a WuXi AppTec company

Category Cell Lysate
Prices $325.00
Sizes 100 µg
Western blot analysis of his-tag SLA (arrow) using his tag antibody. 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the SLA gene

SLA 293T Cell Transient Overexpression Lysate(Denatured) - H00006503-T01 from Acris Antibodies

Category Cell Lysate
Prices $320.00
Sizes 100 µl

SLA overexpression lysate - LY432169 from Acris Antibodies

Category Cell Lysate
Prices $280.00
Sizes 100 µg

SLA 293 Cell Lysate - 407686 from ABBIOTEC

Category Cell Lysate
Prices $392.00
Sizes 100 µg

Slap Overexpression Lysate (Denatured) - H00006503-T01 from Novus Biologicals

Category Cell Lysate
Prices $279.00
Sizes 100 µl

SLA Over-expression Lysate Product - GWB-4F6FFE from Genway Biotech

Category Cell Lysate
Prices $445.00
Sizes 100 µg
Species Human

Slap Overexpression Lysate (Native) - NBP2-11468 from Novus Biologicals

Category Cell Lysate
Prices $329.00
Sizes 100 µg
Western Blot: Slap Overexpression Lysate (Adult Normal) [NBP2-11468] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for Slap.

Panoply™ Human SLA Knockdown Stable Cell Line - CSC-DC014295 from Creative biogene

Category Cell Line
Species Human
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