SLA

Gene Symbol	SLA
Entrez Gene	6503
Alt Symbol	SLA1, SLAP
Species	Human
Gene Type	protein-coding
Description	Src-like-adaptor
Other Description	SLAP-1|hSLAP|src-like-adapter|src-like-adapter protein 1
Swissprots	B7Z4L6 Q6FI01 Q13239 Q9UMQ8 B7Z4J2
Accessions	CAV30731 CBX47476 CBX47477 CBX47478 EAW92159 Q13239 AJ238591 CAB53536 AK297423 BAH12578 AK297519 BAH12602 AK309401 AK310092 AK310108 AK310115 AK311010 AK312584 BAG35478 AW137142 BC007042 AAH07042 BT019994 AAV38797 BX648382 CR536537 CAG38774 D89077 BAA13758 DA483212 DA522819 DA999385 DB265860 DC313073 EU831422 ACE87109 EU831515 ACE86434 U30473 AAC50357 U44403 AAC27662 XM_011517227 XP_011515529 XM_011517228 XP_011515530 NM_001045556 NP_001039021 NM_001045557 NP_001039022 NM_001282964 NP_001269893 NM_001282965 NP_001269894 NM_006748 NP_006739
Function	Adapter protein, which negatively regulates T-cell receptor (TCR) signaling. Inhibits T-cell antigen-receptor induced activation of nuclear factor of activated T-cells. Involved in the negative regulation of positive selection and mitosis of T-cells. May act by linking signaling proteins such as ZAP70 with CBL, leading to a CBL dependent degradation of signaling proteins. {ECO:0000269|PubMed:10449770, ECO:0000269|PubMed:11696592}.
Subcellular Location	Cytoplasm {ECO:0000250}. Endosome {ECO:0000250}. Note=Colocalizes with endosomes. {ECO:0000250}.
Tissue Specificity	Expressed in lung and fetal brain. Weakly expressed in heart, adult brain, placenta, liver, skeletal muscle, kidney and pancreas. {ECO:0000269|PubMed:9660183}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

SLA Antibody Blocking Peptide - LS-E15569 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human Slap Protein - H00006503-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human Slap Protein - H00006503-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

SLA1 Blocking Peptide - 33R-7045 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

SLA - H00006503-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

SLA - H00006503-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

SLA - H00006503-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

SLA - H00006503-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

SLA fusion protein - ag1073 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

SLA fusion protein - Ag13181 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

SEPSECS Human - ENPS-040 from NeoScientific Category Protein Prices $65.00, $169.00, $3,510.00 Sizes 5 µg, 20 µg, 1 mg Source Escherichia Coli. Species Human

Recombinant Human Selenocysteinyl-tRNA(Sec) synthase - BP000905-ENZ-033 from Syd Labs Category Protein Prices $160.00, $2,700.00 Sizes 20 µg, 1 mg Source E. coli-derived. Species Human

SEPSECS - JNV-077 from Reagent Proteins Category Protein Prices $364.00, $2,898.00 Sizes 20.00 µg, 1 mg Source E.coli

Recombinant Human Src-like-adapter(SLA) - CSB-YP613387HU CSB-EP613387HU CSB-BP613387HU CSB-MP613387HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

Selenocysteinyl-tRNA(Sec) synthase Human Recombinant - Pr22118 from ProMab Category Protein Prices $50.00, $130.00, $2,700.00 Sizes 5 μg, 20 μg, 1 mg Source Escherichia Coli. Species Human

SLA Peptide, Human - M34GP14295H from Creative Peptides Category Peptide Source Synthetic. Species Human

Slap Recombinant Protein Antigen - NBP1-80744PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E. coli Species Human

SLA, Recombinant Protein - MBS5304501 from MyBioSource Category Protein Prices $170.00, $595.00 Sizes 100 µg, 1 mg Source E Coli

Src-like-adapter (SLA), Recombinant Protein - MBS1451186 from MyBioSource Category Protein Prices $1,030.00, $1,030.00, $1,260.00, $1,260.00, $1,590.00, $1,590.00, $2,055.00, $2,055.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

Slap Recombinant Protein Antigen - NBP2-56463PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

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